Results 41 to 50 of about 74,508 (147)
Homolog pairing during meiosis : dyneins on the move [PDF]
, 2010 Meiosis is a specialized form of cell division that generates haploid gametes from diploid cells. This is achieved by having 1 round of DNA replication followed by 2 rounds of nuclear division.
Arumugam, Prakash
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Nature Communications, 2019 During meiosis, pairing of homologous chromosomes is critical for sexual reproduction. Here the authors reveal in S. pombe the role of lncRNA–protein complexes during the pairing of homologues chromosomes that assemble at specific chromosomal loci to ...
Da-Qiao Ding +8 more
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Exploiting Homology Information in Nontemplate Based Prediction of Protein Structures [PDF]
, 2015 In this paper we describe a novel strategy for exploring the conformational space of proteins and show that this leads to better models for proteins the structure of which is not amenable to template based methods. Our strategy is based on the assumption
Alfredo Iacoangeli +3 more
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The TERB1 MYB domain suppresses telomere erosion in meiotic prophase I
Cell Reports, 2022 Summary: The meiosis-specific telomere-binding protein TERB1 anchors telomeres to the nuclear envelope and drives chromosome movements for the pairing of homologous chromosomes.
Kexin Zhang +6 more
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Mitotic antipairing of homologous and sex chromosomes via spatial restriction of two haploid sets. [PDF]
, 2018 Pairing homologous chromosomes is required for recombination. However, in nonmeiotic stages it can lead to detrimental consequences, such as allelic misregulation and genome instability, and is rare in human somatic cells.
Hua, Lisa L, Mikawa, Takashi
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Evidence that MEK1 positively promotes interhomologue double-strand break repair [PDF]
, 2010 During meiosis there is an imperative to create sufficient crossovers for homologue segregation. This can be achieved during repair of programmed DNA double-strand breaks (DSBs), which are biased towards using a homologue rather than sister chromatid as ...
Bishop-Bailey, A +5 more
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PLoS Genetics, 2021 Reduction of genome ploidy from diploid to haploid necessitates stable pairing of homologous chromosomes into bivalents before the start of the first meiotic division.
Luisa Vernizzi, Christian F Lehner
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Quantitative dynamics of telomere bouquet formation.
PLoS Computational Biology, 2012 The mechanism by which homologous chromosomes pair during meiosis, as a prelude to recombination, has long been mysterious. At meiosis, the telomeres in many organisms attach to the nuclear envelope and move together to form the telomere bouquet, perhaps
David M Richards +5 more
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Germline progenitors escape the widespread phenomenon of homolog pairing during Drosophila development. [PDF]
PLoS Genetics, 2013 Homolog pairing, which plays a critical role in meiosis, poses a potential risk if it occurs in inappropriate tissues or between nonallelic sites, as it can lead to changes in gene expression, chromosome entanglements, and loss-of-heterozygosity due to ...
Eric F Joyce +3 more
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FIGNL1 Inhibits Non-homologous Chromosome Association and Crossover Formation
Frontiers in Plant Science, 2022 Meiotic crossovers (COs) not only generate genetic diversity but also ensure the accuracy of homologous chromosome segregation. Here, we identified FIGNL1 as a new inhibitor for extra crossover formation in rice.
Shuying Yang +13 more
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