Results 251 to 260 of about 773,827 (377)

Comprehensive RAD51C ovarian cancer variant analysis uncouples homologous recombination and replicative functions. [PDF]

Nat Commun
Rein HL, Rawal Y, Palovcak-Lightbourn AL, Ganesan GS, Parker PS, Russell R, Darrah KE, Afsar M, Sullivan MR, Hengel SR, Radke MR, Opresko PL, Yanowitz JL, Greene EC, Lee JM, Domchek SM, Swisher EM, Olsen SK, Sung P, Bernstein KA.   +19 more
europepmc   +1 more source

Comments on important genetic topics from papers in other journals: Prospects for homologous recombination in human gene therapy [PDF]

, 1992
J C K Barber
openalex   +1 more source

The PP2A‐B56 Binding Site LxxIxE Contributes to Asp‐Mediated Spindle Pole Stability

Cytoskeleton, EarlyView.
ABSTRACT The organization of microtubules into a mitotic spindle is critical for animal cell proliferation and involves the cooperation of hundreds of proteins whose molecular roles and regulation are not fully understood. The protein product of the Drosophila gene abnormal spindle, Asp, is a microtubule‐associated protein required for correct mitotic ...
Margaux Quiniou, Maria C. Burns, Aynsley McDermott, Karolina Jaworek, Stacey J. Scott, James G. Wakefield, Lori Borgal   +6 more
wiley   +1 more source

Breast carcinomas associated with microglandular adenosis are linked to germline alterations in homologous recombination-deficiency genes. [PDF]

NPJ Breast Cancer
Schwartz CJ, Genco I, Repetto M, Muldoon D, Gazzo A, Terraf P, Grabenstetter A, Ross D, Zhang H, Mandelker D, Powell S, Weigelt B, Bandlamudi C, Brogi E, Pareja F, Wen HY.   +15 more
europepmc   +1 more source

PEK14: A Kinesin‐4 Necessary for Male‐Derived Fertility in Arabidopsis thaliana

Cytoskeleton, EarlyView.
ABSTRACT Of the 61 kinesins annotated in Arabidopsis thaliana, many are still without assigned function. Here, we have screened an insertional mutant library of Arabidopsis pollen‐expressed kinesins for fertility defects. Insertional mutants for three kinesins showed a significant reduction in seed set.
Isabella N. Mendes, Norman R. Groves, Jessica Z. Li, Lily N. Thompson, Brian J. Smith, Aman Y. Husbands, Iris Meier   +6 more
wiley   +1 more source

Curcumin Induces Homologous Recombination Deficiency by BRCA2 Degradation in Breast Cancer and Normal Cells. [PDF]

Cancers (Basel)
Komar ZM, Ladan MM, Verkaik NS, Dahmani A, Montaudon E, Marangoni E, Kanaar R, Nonnekens J, Houtsmuller AB, Jager A, Gent DCV.   +10 more
europepmc   +1 more source

A BCR-ABLp190 Fusion Gene Made by Homologous Recombination Causes B-Cell Acute Lymphoblastic Leukemias in Chimeric Mice With Independence of the Endogenous bcr Product [PDF]

, 1997
Andrés Castellanos‐Martín, Belén Pintado, Eduardo Weruaga, R. Arévalo, Andrew Lopez, Alberto Órfão, Isidro Sánchez‐García   +6 more
openalex   +1 more source

Nuclear Entanglement: New Insights Into the Role of Cytoskeleton and Nucleoskeleton in Plant Nuclear Function

Cytoskeleton, EarlyView.
ABSTRACT Of the three types of cytoskeleton known in animals—actin, microtubules, and intermediate filaments—only actin and microtubules exist in plants. Both play important roles in cellular shaping, organelle movement, organization of the endomembrane system, and cell signaling.
Norman R. Groves, Katelyn Amstutz, Lily A. Schumacher, Iris Meier   +3 more
wiley   +1 more source

USP4 Auto-Deubiquitylation Promotes Homologous Recombination. [PDF]

Mol Cell
Wijnhoven P, Konietzny R, Blackford AN, Travers J, Kessler BM, Nishi R, Jackson SP.   +6 more
europepmc   +1 more source

Lineage labeling with zebrafish hand2 Cre and CreERT2 recombinase CRISPR knock‐ins

Developmental Dynamics, EarlyView.
Abstract Background The ability to generate endogenous Cre recombinase drivers using CRISPR‐Cas9 knock‐in technology allows lineage tracing, cell type‐specific gene studies, and in vivo validation of inferred developmental trajectories from phenotypic and gene expression analyses. This report describes endogenous zebrafish hand2 Cre and CreERT2 drivers
Zhitao Ming, Fang Liu, Hannah R. Moran, Robert L. Lalonde, Megan Adams, Nicole K. Restrepo, Parnal Joshi, Stephen C. Ekker, Karl J. Clark, Iddo Friedberg, Saulius Sumanas, Chunyue Yin, Christian Mosimann, Jeffrey J. Essner, Maura McGrail   +14 more
wiley   +1 more source