Results 251 to 260 of about 348,739 (321)

Mechanism of Rad51 filament formation by Rad52 and Rad55-Rad57 in homologous recombination. [PDF]

open access: yesNat Commun
Deveryshetty J   +13 more
europepmc   +1 more source

Role of the Choline‐Binding Protein A in the Ability of Porcine Ligilactobacillus salivarius FFIG58 to Modulate TLR3‐Mediated Intestinal Antiviral Immunity

open access: yesFood Frontiers, EarlyView.
The choline‐binding protein A (CbpA) was shown to mediate adhesion of probiotic Ligilactobacillus salivarius strains to human intestinal epithelial cells (IECs). A knockout mutant lacking the CbpA protein derived from the immunomodulatory porcine strain L. salivarius FFIG58 was obtained. The CbpA is a key surface protein of L.
Yoshiya Imamura   +13 more
wiley   +1 more source

Eccrine carcinomas and homologous recombination repair cancer predisposition genes: A case series. [PDF]

open access: yesJAAD Case Rep
Morecroft R   +10 more
europepmc   +1 more source

Protocol for Constructing a Gene Knockout in Pseudomonas Using pT18mobsacB

open access: yesFood Safety and Health, EarlyView.
A streamlined protocol for scarless gene knockout in Pseudomonas using the tetracycline‐resistant suicide plasmid pT18mobsacB is presented. The method enables efficient two‐step allelic exchange and is broadly applicable to Gram‐negative bacteria. ABSTRACT Gene knockout via homologous recombination is a powerful approach for investigating gene function
Han Yang   +4 more
wiley   +1 more source

CG>TG mutation frequency as negative predictor of homologous recombination deficiency in ovarian and breast cancer. [PDF]

open access: yesCommun Biol
Romanovsky E   +8 more
europepmc   +1 more source

Identification of Cathepsin H and Metabolic Traits as Potential Biomarkers for Lung Cancer by Mendelian Randomization and Single‐Cell Transcriptomics

open access: yesAdvanced Genetics, EarlyView.
This study explores the link between CTSH and lung cancer, covering global trends in lung cancer and hyperglycemia, MR analysis of CTSH and 233 metabolic traits, and scRNA analysis, along with multi‐level validation of CTSH expression in LUAD. These findings offer valuable insights into lung cancer biology and provide new perspectives for biomarker ...
Chenghu Song   +9 more
wiley   +1 more source

From Genomic Fossils to Functional Elements: The Evolving Story of Pseudogenes

open access: yesAdvanced Genetics, EarlyView.
This review begins with an introduction, summarizing the research background in pseudogene studies. It then contains three aspects: identification of pseudogenes, detailing their classification and features in metazoan genomes; functional pseudogenes, introducing their reactivation and regulation mechanisms; and pseudogenes’ contribution to species ...
Mengyao Sun, Yanni Ma, Jia Yu
wiley   +1 more source

Home - About - Disclaimer - Privacy