Results 31 to 40 of about 345,396 (332)

Phylogenetic evidence for homologous recombination within the family Birnaviridae [PDF]

, 2008
Birnaviruses are bi-segmented double-stranded RNA (dsRNA) viruses infecting insects, avian species and a wide range of aquatic species. Although homologous recombination is a common phenomenon in positive-sense RNA viruses, recombination in dsRNA viruses
Hon, CC, Jiang, J, Lam, TTY, Leung, FCC, Shi, M, Wong, RTY, Yip, CW, Zeng, F   +7 more
core   +1 more source

Regulation Mechanisms of Meiotic Recombination Revealed from the Analysis of a Fission Yeast Recombination Hotspot ade6-M26

Biomolecules, 2022
Meiotic recombination is a pivotal event that ensures faithful chromosome segregation and creates genetic diversity in gametes. Meiotic recombination is initiated by programmed double-strand breaks (DSBs), which are catalyzed by the conserved Spo11 ...
Kouji Hirota
doaj   +1 more source

Homolog pairing during meiosis : dyneins on the move [PDF]

, 2010
Meiosis is a specialized form of cell division that generates haploid gametes from diploid cells. This is achieved by having 1 round of DNA replication followed by 2 rounds of nuclear division.
Arumugam, Prakash
core   +1 more source

Mutations in pathways depending on BRCA1 and BRCA2 may increase cancer risks from an environmental carcinogen [PDF]

, 2011
Recently, the President’s Cancer Panel [2008-2009] protested that preventive action is not taken when uncertainty exists about potential harm from a chemical, because the US regulatory approach demands that a hazard be incontrovertibly ...
Bernard Friedenson
core   +2 more sources

The Landscape of Realized Homologous Recombination in Pathogenic Bacteria [PDF]

, 2015
Recombination enhances the adaptive potential of organisms by allowing genetic variants to be tested on multiple genomic backgrounds. Its distribution in the genome can provide insight into the evolutionary forces that underlie traits, such as the ...
Didelot, X, Falush, D, Jolley, KA, Kobayashi, I, Maiden, MCJ, Sheppard, SK, Yahara, K   +6 more
core   +2 more sources

Mouse WRN Helicase Domain Is Not Required for Spontaneous Homologous Recombination-Mediated DNA Deletion

Journal of Nucleic Acids, 2010
Werner syndrome is a rare disorder that manifests as premature aging and age-related diseases. WRN is the gene mutated in WS, and is one of five human RecQ helicase family members.
Adam D. Brown, Alison B. Claybon, Alexander J. R. Bishop   +2 more
doaj   +1 more source

Improved Gene Targeting through Cell Cycle Synchronization. [PDF]

PLoS ONE, 2015
Gene targeting is a challenge in organisms where non-homologous end-joining is the predominant form of recombination. We show that cell division cycle synchronization can be applied to significantly increase the rate of homologous recombination during ...
Vasiliki Tsakraklides, Elena Brevnova, Gregory Stephanopoulos, A Joe Shaw   +3 more
doaj   +1 more source

Arabidopsis RecQl4A suppresses homologous recombination and modulates DNA damage responses [PDF]

, 2005
The DNA damage response and DNA recombination are two interrelated mechanisms involved in maintaining the integrity of the genome, but in plants they are poorly understood.
Bachrati, Bagherieh-Najjar, Bai, Blackburn, Bundock, Cohen, Courcelle, Cromie, De Silva, Dellaporta, Ellis, Fitzgerald, Frei, Gallego, Gallego, Gallego, Gherbi, Gray, Hanada, Hanin, Harrigan, Hartung, Henson, Imamura, Jackson, Jacques Hille, Johnson, Kitao, Krysan, Li, Lovett, Lowndes, McGlynn, McHugh, Mengiste, Michel, Mohammad B. Bagherieh-Najjar, Nakayama, Nakayama, Nugent, Onno M.H. Vries, Osborn, Pastink, Paul P. Dijkwel, Pierce, Puchta, Reiss, Riha, Riha, Rothstein, Sambrook, Seigneur, Sengupta, Sessions, Simon, Sinclair, Sladek, Sundaresan, Swoboda, Tercero, Ui, Valvekens, Watt, Wu, Yamagata   +64 more
core   +7 more sources

Using single loxP sites to enhance homologous recombination: ts mutants in Sec1 of Dictyostelium discoideum.

PLoS ONE, 2007
BackgroundDictyostelium discoideum amoebae are haploid and, as they share many features with animal cells, should be an ideal creature for studying basic processes such as cell locomotion.
Mark S Bretscher, Margaret Clotworthy
doaj   +1 more source

V_H replacement in rearranged immunoglobulin genes [PDF]

, 2005
Examples suggesting that all or part of the V_H segment of a rearranged V_HDJ_H may be replaced by all or part of another V_H have been appearing since the 1980s ...
Brokaw JL, Cascalho M, Choi Y, Chukwuocha RU, Covey LR, Cuomo CA, Deane M, Golub R, Han JO, Hesse JE, Kleinfield RW, Kobrin CB, Lewis SM, Ramsden DA, Rosenquist R, Shiokawa S, Sims GP, Steenbergen EJ, Steenbergen EJ, Taki S, Wasserman R, Wasserman R   +21 more
core   +2 more sources