Results 31 to 40 of about 789,870 (314)

Sister chromatid exchanges induced by perturbed replication can form independently of BRCA1, BRCA2 and RAD51

open access: yesNature Communications, 2022
Sister chromatid exchanges (SCEs) are considered to be products of homologous recombination repair. The authors show that SCEs can arise independently of homologous recombination due to processing of replication intermediates during mitosis.
Anne Margriet Heijink   +18 more
doaj   +1 more source

Homologous Recombination under the Single-Molecule Fluorescence Microscope [PDF]

open access: yes, 2019
Homologous recombination (HR) is a complex biological process and is central to meiosis and for repair of DNA double-strand breaks. Although the HR process has been the subject of intensive study for more than three decades, the complex protein–protein ...
Dhakal, Soma, Gibbs, Dalton R.
core   +2 more sources

No observed effect of homologous recombination on influenza C virus evolution

open access: yesVirology Journal, 2010
The occurrence of homologous recombination in influenza viruses has been under some debate recently. To determine the extent of homologous recombination in influenza C virus, recombination analyses of all available gene sequences of influenza C virus ...
Boni Maciej F, Han Guan-Zhu, Li Si-Shen
doaj   +1 more source

Rad54: the Swiss Army knife of homologous recombination? [PDF]

open access: yes, 2006
Homologous recombination (HR) is a ubiquitous cellular pathway that mediates transfer of genetic information between homologous or near homologous (homeologous) DNA sequences. During meiosis it ensures proper chromosome segregation in the first division.
Heyer, Wolf-Dietrich   +3 more
core   +2 more sources

Phylogenetic evidence for homologous recombination within the family Birnaviridae [PDF]

open access: yes, 2008
Birnaviruses are bi-segmented double-stranded RNA (dsRNA) viruses infecting insects, avian species and a wide range of aquatic species. Although homologous recombination is a common phenomenon in positive-sense RNA viruses, recombination in dsRNA viruses
Hon, CC   +7 more
core   +1 more source

Homologous recombination and the repair of DNA double-strand breaks

open access: yesJournal of Biological Chemistry, 2018
Homologous recombination enables the cell to access and copy intact DNA sequence information in trans, particularly to repair DNA damage affecting both strands of the double helix.
W. D. Wright, S. Shah, W. Heyer
semanticscholar   +1 more source

Homolog pairing during meiosis : dyneins on the move [PDF]

open access: yes, 2010
Meiosis is a specialized form of cell division that generates haploid gametes from diploid cells. This is achieved by having 1 round of DNA replication followed by 2 rounds of nuclear division.
Arumugam, Prakash
core   +1 more source

Mutations in pathways depending on BRCA1 and BRCA2 may increase cancer risks from an environmental carcinogen [PDF]

open access: yes, 2011
Recently, the President’s Cancer Panel [2008-2009] protested that preventive action is not taken when uncertainty exists about potential harm from a chemical, because the US regulatory approach demands that a hazard be incontrovertibly ...
Bernard Friedenson
core   +2 more sources

Regulation Mechanisms of Meiotic Recombination Revealed from the Analysis of a Fission Yeast Recombination Hotspot ade6-M26

open access: yesBiomolecules, 2022
Meiotic recombination is a pivotal event that ensures faithful chromosome segregation and creates genetic diversity in gametes. Meiotic recombination is initiated by programmed double-strand breaks (DSBs), which are catalyzed by the conserved Spo11 ...
Kouji Hirota
doaj   +1 more source

The Landscape of Realized Homologous Recombination in Pathogenic Bacteria [PDF]

open access: yes, 2015
Recombination enhances the adaptive potential of organisms by allowing genetic variants to be tested on multiple genomic backgrounds. Its distribution in the genome can provide insight into the evolutionary forces that underlie traits, such as the ...
Didelot, X   +6 more
core   +2 more sources

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