Results 31 to 40 of about 773,827 (377)

Sister chromatid exchanges induced by perturbed replication can form independently of BRCA1, BRCA2 and RAD51

open access: yesNature Communications, 2022
Sister chromatid exchanges (SCEs) are considered to be products of homologous recombination repair. The authors show that SCEs can arise independently of homologous recombination due to processing of replication intermediates during mitosis.
Anne Margriet Heijink   +18 more
doaj   +1 more source

Rad54: the Swiss Army knife of homologous recombination? [PDF]

open access: yes, 2006
Homologous recombination (HR) is a ubiquitous cellular pathway that mediates transfer of genetic information between homologous or near homologous (homeologous) DNA sequences. During meiosis it ensures proper chromosome segregation in the first division.
Heyer, Wolf-Dietrich   +3 more
core   +2 more sources

No observed effect of homologous recombination on influenza C virus evolution

open access: yesVirology Journal, 2010
The occurrence of homologous recombination in influenza viruses has been under some debate recently. To determine the extent of homologous recombination in influenza C virus, recombination analyses of all available gene sequences of influenza C virus ...
Boni Maciej F, Han Guan-Zhu, Li Si-Shen
doaj   +1 more source

Homologous Recombination under the Single-Molecule Fluorescence Microscope [PDF]

open access: yes, 2019
Homologous recombination (HR) is a complex biological process and is central to meiosis and for repair of DNA double-strand breaks. Although the HR process has been the subject of intensive study for more than three decades, the complex protein–protein ...
Dhakal, Soma, Gibbs, Dalton R.
core   +2 more sources

Phylogenetic evidence for homologous recombination within the family Birnaviridae [PDF]

open access: yes, 2008
Birnaviruses are bi-segmented double-stranded RNA (dsRNA) viruses infecting insects, avian species and a wide range of aquatic species. Although homologous recombination is a common phenomenon in positive-sense RNA viruses, recombination in dsRNA viruses
Hon, CC   +7 more
core   +1 more source

Recombination: Homologous recombination branches out [PDF]

open access: yesCurrent Biology, 2001
Homologous recombination can be divided into three key steps: strand exchange, branch migration and resolution. The identification of a protein complex that catalyses branch migration and Holliday junction resolution argues that the mechanism of homologous recombination is conserved from bacteria to man.
openaire   +3 more sources

SUMOylation of Rad52-Rad59 synergistically change the outcome of mitotic recombination [PDF]

open access: yes, 2016
Homologous recombination (HR) is essential for maintenance of genome stability through double-strand break (DSB) repair, but at the same time HR can lead to loss of heterozygosity and uncontrolled recombination can be genotoxic.
Lisby, Michael, Silva, Sonia
core   +1 more source

Bacterial microevolution and the Pangenome [PDF]

open access: yes, 2020
The comparison of multiple genome sequences sampled from a bacterial population reveals considerable diversity in both the core and the accessory parts of the pangenome.
A Bankevich   +68 more
core   +1 more source

Homologous recombination and the repair of DNA double-strand breaks

open access: yesJournal of Biological Chemistry, 2018
Homologous recombination enables the cell to access and copy intact DNA sequence information in trans, particularly to repair DNA damage affecting both strands of the double helix.
W. D. Wright, S. Shah, W. Heyer
semanticscholar   +1 more source

Regulation Mechanisms of Meiotic Recombination Revealed from the Analysis of a Fission Yeast Recombination Hotspot ade6-M26

open access: yesBiomolecules, 2022
Meiotic recombination is a pivotal event that ensures faithful chromosome segregation and creates genetic diversity in gametes. Meiotic recombination is initiated by programmed double-strand breaks (DSBs), which are catalyzed by the conserved Spo11 ...
Kouji Hirota
doaj   +1 more source

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