Results 161 to 170 of about 36,553 (257)

Evaluation of Safety, Immunogenicity and Efficacy of an Inactivated Bovine Viral Diarrhea Virus (BVDV-1) Vaccine Candidate in Cattle. [PDF]

Viruses
Kalaiyarasu S, Mishra N, Sudhakar SB, Singh VP, Sanyal A.   +4 more
europepmc   +1 more source

Hydroxamic Acids as HDAC Inhibitor Drug Leads for Malaria

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a global health threat, with an estimated 282 million cases and 610,000 malaria‐associated deaths reported in 2024. Most mortality is due to infection by Plasmodium falciparum parasites, with the highest burden occurring in Sub‐Saharan Africa.
Wisam A. Dawood, Jacinta R. Macdonald, Christian Anzenhofer, Tina S. Skinner‐Adams, Robert C. Reid, Thomas Kurz, David P. Fairlie, Katherine T. Andrews   +7 more
wiley   +1 more source

Dynamics of HIV reservoirs following repeated anti-SARS-CoV-2 vaccination. [PDF]

Front Immunol
Lu J, Ahmad A, Chomont N, Costiniuk CT.
europepmc   +1 more source

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

Longitudinal Antibody Dynamics Following SARS-CoV-2 Viral-Vectored and mRNA Booster Vaccination in Ghanaian Adults. [PDF]

Vaccines (Basel)
Partey FD, Mohammed H, Osei F, Pobee ANA, Atta-Poku DE, Ansah YA, Owusu-Amponsah MMAK, Appiah NYA, Koranteng NAO, Appiagyei-Mintah E, Brenko T, Nartey S, Quashie PK, Ofori MF, Kusi KA.   +14 more
europepmc   +1 more source

Advances and challenges in experimental models for Epstein–Barr virus research

mLife, EarlyView.
Abstract Epstein–Barr virus (EBV), the first identified human oncovirus, is a ubiquitous γ‐herpesvirus etiologically linked to diverse malignancies, lymphoproliferative disorders, and autoimmune diseases. Experimental models are pivotal for unraveling the infection and pathogenesis mechanisms, life cycle regulation, as well as development and ...
Gulimire Wufuer, Jiabao Tang, Tingdong Li, Shengxiang Ge, Jun Zhang, Ningshao Xia   +5 more
wiley   +1 more source

Prime editing in neuropsychiatric disorders: From mutation‐specific target selection to clinical translation

Neuroprotection, EarlyView.
Abstract Prime editing, a novel clustered regularly interspaced short palindromic repeats (CRISPR)‐based technology, fuses a reverse transcriptase (RT) to an engineered CRISPR‐associated protein 9 (Cas9) and uses a prime editing guide RNA (pegRNA)‐encoded template.
Tianshan Ji, Yuan Zhang, Jinyi Zhao, Yiping Lu, Chengkun Wang   +4 more
wiley   +1 more source

Cross-Protection in PRRSV: Mechanisms, Limitations, and Implications for Vaccine Design. [PDF]

Pathogens
Raev SA, Cai L, Muro N, Madera R, Wang L, Shi J.   +5 more
europepmc   +1 more source

Exploring eco‐evolutionary and temporal patterns of arbuscular mycorrhizal fungal communities colonizing Sorghum bicolor across sites of contrasting land use history and climate

PLANTS, PEOPLE, PLANET, EarlyView.
Sorghum bicolor is a globally important cereal crop with annual yields exceeding 50 million tons across more than 100 countries and can be grown on marginal lands where conventional agriculture is limited. We examined how eight genetically diverse sorghum genotypes shaped arbuscular mycorrhizal fungal (AMF) community assembly across two contrasting ...
Philip Brailey‐Crane, Sedona M. Spann, Thomas H. Pendergast IV, Ben J. Long, Ashton K. Brinkley, Sarah R. Mondibrown, Nancy C. Johnson, Katrien M. Devos, Jeffrey L. Bennetzen   +8 more
wiley   +1 more source

Characteristics of SARS-CoV-2 Reinfection and Ancestral RBD-Blocking Antibody Levels: A Cross-Sectional Study in the Post-Zero-COVID Era from Shanghai. [PDF]

Vaccines (Basel)
Chen C, Zhu Y, Wang H, Wu F, Xie Y, Jia Q, Yang Y, Lyu J, Qu J, Wang Q, Wu F.   +10 more
europepmc   +1 more source