Results 191 to 200 of about 473,693 (291)

Lactobacillus johnsonii attenuates ovarian aging by remodeling the gut–ovary axis

iMetaOmics, EarlyView.
Aging is accompanied by a reduced abundance of L. johnsonii and ovarian decline. Supplementation with L. johnsonii elevates microbial IPA production via the LdhA enzyme and commensal bacteria. IPA activates the AhR/YAP signaling axis, promoting YAP nuclear translocation and inducing the expression of downstream target genes CYR61 and CTGF. This cascade
Jiamin He, Qiwen Wang, Luyi Chen, Yadong Qi, Dingjiacheng Jia, Jilei Xu, Qingyi Wang, Yao Jiang, Jian Zhou, Yong Sun, Ruochen Yan, Lan Wang, Tongyao Hou, Zheng Kuang, Min Jin, Liangjing Wang, Shujie Chen   +16 more
wiley   +1 more source

Clinical Characteristics of Vaccinated and Unvaccinated Patients Who Died from COVID-19: A Retrospective Comparative Study. [PDF]

Vaccines (Basel)
Işler Y, Kaya H, Ortabük AF, Yüksel M, Ay MO.   +4 more
europepmc   +1 more source

Unveiling chemical composition of peppermint oil and its bioactivities compared with (R)‐(+)‐limonene: antimicrobial, antibiofilm, and insecticidal perspectives

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Peppermint (Mentha piperita L.) essential oil (MPEO) is recognized for its broad‐spectrum antimicrobial properties and potential applications in food preservation. This study aimed to determine whether the bioactivity of MPEO is attributable to (R)‐(+)‐limonene or whether the complete essential oil provides higher efficacy due to ...
Miroslava Kačániová, Stefania Garzoli, Minhang Qiao, Zhaojun Ban, Li Li, Jian Lou, Joel Horacio Elizondo‐Luevano, Wissem Mnif, Alessandro Bianchi, Rania Ben Saad, Anis Ben Hsouna   +10 more
wiley   +1 more source

Immunogenicity of Two Versus Three Doses of Hepatitis B Vaccine When Administered to Children Aged 2-18 Months: A Randomized Clinical Trial. [PDF]

J Infect Dis
Kegbevi KB, Febriani Y, Sauvageau C, Ursu MM, Quach C, Desjardins M, Bestman-Smith J, Gilca V, Brousseau N.   +8 more
europepmc   +1 more source

Prime editing in neuropsychiatric disorders: From mutation‐specific target selection to clinical translation

Neuroprotection, EarlyView.
Abstract Prime editing, a novel clustered regularly interspaced short palindromic repeats (CRISPR)‐based technology, fuses a reverse transcriptase (RT) to an engineered CRISPR‐associated protein 9 (Cas9) and uses a prime editing guide RNA (pegRNA)‐encoded template.
Tianshan Ji, Yuan Zhang, Jinyi Zhao, Yiping Lu, Chengkun Wang   +4 more
wiley   +1 more source

Applications of nanocarrier‐delivered RNA interference in agricultural biological control (2009–2025)

New Plant Protection, EarlyView.
Despite 17 years of development, the effectiveness of nanocarrier‐delivered RNAi pesticide (NDRP) for agricultural biological control remains limited. The successful development of effective NDRP development requires the coordinated optimization of target gene selection and nanocarrier properties, including RNA dosage, multi‐gene targeting, protection ...
Shi Dong Wang, Woo‐Jong Hong, Xu Jiang, Ki‐hong Jung, Yuan Hu Xuan   +4 more
wiley   +1 more source

Immunization with an <i>Escherichia coli</i>-Produced Hepatitis E Virus Genotype 3 Virus-like Particle (HEV-3_p495) Confers Protection Against HEV-3 and HEV-4 Challenge in Pigs. [PDF]

Viruses
Kunita S, Takahashi M, Kobayashi T, Murata K, Okamoto H.   +4 more
europepmc   +1 more source

Evolutionary trade‐offs between beauvericin production and growth define divergent virulence strategies in Beauveria

Pest Management Science, EarlyView.
Two virulence strategies in Beauveria: a growth strategy characterized by rapid within‐host proliferation, and a toxin strategy involving antimicrobial activity and toxicity to insects Abstract BACKGROUND Pathogen virulence is often attributed to toxin production, yet toxins are metabolically costly and may not universally enhance fitness.
Shasha Hu, Lana L B de Carvalho, Ricardo A Polanczyk, Michael J Bidochka   +3 more
wiley   +1 more source

Long-term immunity and protection against SARS-CoV-2 XBB.1.5 following homologous and heterologous mRNA and MVA vaccination. [PDF]

Front Immunol
Pérez P, Esteso G, García-García I, Flores S, Sánchez-Corzo C, Noriega MA, Casasnovas JM, Esteban M, García-Arriaza J.   +8 more
europepmc   +1 more source

From knowledge to action: the importance of characterizing herbicide resistance mechanisms for implementing management strategies

Pest Management Science, EarlyView.
This review bridges the gap between understanding resistance mechanisms and applying them in weed management, highlighting how mechanistic insights reveal vulnerabilities that can guide more effective control strategies. Abstract Herbicide resistance remains one of the most intensively studied areas in weed science because of its direct consequences ...
Luan Cutti, Eric L. Patterson, Todd A. Gaines, Aldo Merotto   +3 more
wiley   +1 more source