Results 71 to 80 of about 305,462 (309)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

El concepto de homología filogenética y la selección de caracteres taxonómicos

open access: yesBotan‪ical Sciences, 1996
The practical problem of selecting taxonomic characters not only requires an extensive empirical basis. It also demands an examination of theories and epistemological principles behind character analysis.
Efraín de Luna, Brenth D. Mishler
doaj   +1 more source

Default Mode Network Analysis of APOE Genotype in Cognitively Unimpaired Subjects Based on Persistent Homology

open access: yesFrontiers in Aging Neuroscience, 2020
Current researches on default mode network (DMN) in normal elderly have mainly focused on finding some dysfunctional areas with decreased or increased connectivity. The global network dynamics of apolipoprotein E (APOE) e4 allele group is rarely studied.
Liqun Kuang   +6 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Cubical Homotopy and Homology Groups [PDF]

open access: yes, 2022
We define and study homotopy and homology groups of cubical sets. To this end, we give four definitions of homotopy groups of a cubical set, prove that they are equivalent, and further that they agree with their topological analogues via the geometric ...
Carranza, Daniel Josue
core   +1 more source

Unraveling chaos: A topological analysis of simplicial homology groups and their foldings

open access: yesOpen Mathematics
In this article, we introduce a new type of simplicial homology group called the chaotic simplicial homology group. We construct the structure of this group and obtain some types of conditional foldings and unfoldings restricted to the elements of the ...
Abu-Saleem Mohammed
doaj   +1 more source

Pirashvili–Richter-type theorems for the reflexive and dihedral homology theories

open access: yesComptes Rendus. Mathématique
Reflexive homology and dihedral homology are the homology theories associated to the reflexive and dihedral crossed simplicial groups respectively. The former has recently been shown to capture interesting information about $C_2$-equivariant homotopy ...
Graves, Daniel
doaj   +1 more source

Adaptive Discrete Vector Field in Sensor Networks

open access: yesSensors, 2018
Homology groups are a prime tool for measuring the connectivity of a network, and their computation in a distributed and adaptive way is mandatory for their use in sensor networks.
Mengyi Zhang, Alban Goupil
doaj   +1 more source

Novel Variants of Citrus Viroid-III in Fars Province [PDF]

open access: yesمجله بیوتکنولوژی کشاورزی, 2011
Citrus viroid-III (CVd-III) has narrow host range and induces specific symptoms on Etrog citron consist of petiole wrinkle and browning plus leaf twist, leaf droop and bent leaf induced by point necroses of the mid vein.
Aliakbar Bagherian   +1 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

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