Results 1 to 10 of about 46,167 (302)

Decoupled tricarboxylic acid cycle and glycolysis of Corynebacterium glutamicum combined with acetate supply promote high-yield biosynthesis of l-homoserine [PDF]

Synthetic and Systems Biotechnology
l-Homoserine is a valuable intermediate with broad applications in the food, pharmaceutical, and chemical industries. Although Corynebacterium glutamicum has been engineered for the efficient biosynthesis of l-homoserine, both production efficiency and ...
Daobin Wang, Lu Xu, Junwen Yuan, Ruisi Wu, Xiyao Cheng, Jidong Liu, Ning Li   +6 more
doaj   +2 more sources

Directed evolution of Vibrio fischeri LuxR for improved response to butanoyl-homoserine lactone [PDF]

, 2007
LuxR is the 3-oxohexanoyl-homoserine lactone (3OC6HSL) dependent transcriptional activator of the prototypical acyl-homoserine lactone (AHL) quorum sensing system of Vibrio fischeri.
Arnold, Frances H., Hauer, Bernhard, Hawkins, Andrew C., Leadbetter, Jared R., Stuermer, Rainer   +4 more
core   +4 more sources

Identification of Quorum-Sensing Molecules of N-Acyl-Homoserine Lactone in Gluconacetobacter Strains by Liquid Chromatography-Tandem Mass Spectrometry

Molecules, 2019
Many Gram-negative bacteria can regulate gene expression in a cell density-dependent manner via quorum-sensing systems using N-acyl-homoserine lactones (AHLs), which are typical quorum-sensing signaling molecules, and thus modulate physiological ...
Ling-Pu Liu, Long-Hui Huang, Xiao-Tong Ding, Lin Yan, Shi-Ru Jia, Yu-Jie Dai, Yan-Yan Xie, Cheng Zhong   +7 more
doaj   +2 more sources

Priming winter wheat seeds with the bacterial quorum sensing signal N-hexanoyl-L-homoserine lactone (C6-HSL) shows potential to improve plant growth and seed yield [PDF]

bioRxiv, 2019
Several model plants are known to respond to bacterial quorum sensing molecules with altered root growth and gene expression patterns and induced resistance to plant pathogens.
Babenko, Lidia M., Foster, Jessica, Iungin, Olga S., Kosakivska, Iryna V., Moshynets, Olena V., Potters, Geert, Rogalsky, Sergiy P., Spiers, Andrew J.   +7 more
core   +3 more sources

Isolation and Characterization of N-acyl Homoserine Lactone-Producing Bacteria From Cattle Rumen and Swine Intestines

Frontiers in Cellular and Infection Microbiology, 2018
Quorum sensing systems regulate gene expression in response to bacterial population density. Acyl-homoserine lactones are a class of quorum sensing molecules found in cattle rumen that are thought to regulate the gene expression of enterohemorrhagic ...
Yang Yang, Yang Yang, Yang Yang, Mingxu Zhou, Mingxu Zhou, Philip R. Hardwidge, Hengmi Cui, Guoqiang Zhu, Guoqiang Zhu   +8 more
doaj   +2 more sources

Cofactor engineering for improved production of 2,4-dihydroxybutyric acid via the synthetic homoserine pathway [PDF]

Frontiers in Bioengineering and Biotechnology
(L)-2,4-dihydroxybutyrate (DHB) is a versatile compound that can serve as a precursor for the synthesis of the methionine analog 2-hydroxy-4-(methylthio)butyrate and new advanced polymers.
Nadine Ihle, Laura Grüßner, Ceren Alkim, T. A. Stefanie Nguyen, Thomas Walther, Cláudio J. R. Frazão   +5 more
doaj   +2 more sources

The RhlR quorum-sensing receptor controls Pseudomonas aeruginosa pathogenesis and biofilm development independently of its canonical homoserine lactone autoinducer.

PLoS Pathogens, 2017
Quorum sensing (QS) is a bacterial cell-to-cell communication process that relies on the production, release, and response to extracellular signaling molecules called autoinducers.
Sampriti Mukherjee, Dina Moustafa, Chari D Smith, Joanna B Goldberg, Bonnie L Bassler   +4 more
doaj   +2 more sources

Homoserine and quorum-sensing acyl homoserine lactones as alternative sources of threonine:A potential role for homoserine kinase in insect-stage Trypanosoma brucei [PDF]

Molecular Microbiology, 2014
10.1111/mmi.12853Molecular Microbiology951143 ...
Chia K.S., Cima I., Foong Y.M., Goh W.L., Gong M., Hillmer A.M., Koh P.K., Kong S.L., Lee D.Y.S., Lee E.X.W., Lim B., Lim W.-Y., Mohamed Suhaimi N.-A., Phyo W.M., Tan M.-H., Ying J.Y.   +15 more
core   +6 more sources

Metabolic engineering strategies for L-Homoserine production in Escherichia coli [PDF]

Microbial Cell Factories
L-Homoserine, serves as a non-essential precursor for the essential amino acids derived from L-aspartate in both animals and humans. It finds widespread applications across the food, cosmetics, pharmaceutical, and animal feed industries.
Xin Jin, Sumeng Wang, Yanbing Wang, Qingsheng Qi, Quanfeng Liang   +4 more
doaj   +2 more sources

Identification, synthesis and regulatory function of the N-acylated homoserine lactone signals produced by Pseudomonas chlororaphis HT66

Microbial Cell Factories, 2018
Background Pseudomonas chlororaphis HT66 isolated from the rice rhizosphere is an important plant growth-promoting rhizobacteria that produce phenazine-1-carboxamide (PCN) in high yield.
Huasong Peng, Yi Ouyang, Muhammad Bilal, Wei Wang, Hongbo Hu, Xuehong Zhang   +5 more
doaj   +2 more sources