The aggregation of Brucella abortus occurs under microaerobic conditions and promotes desiccation tolerance and biofilm formation [PDF]
, 2012 Brucella abortus causes brucellosis mainly in cattle. The infection is transmitted to humans by ingestion of animal products or direct contact with infected material.
Almiron, Marta A. +2 more
core +1 more source
Deciphering the Symbiotic Significance of Quorum Sensing Systems of Sinorhizobium fredii HH103 [PDF]
, 2020 Quorum sensing (QS) is a bacterial cell-to-cell signaling mechanism that collectively regulates and synchronizes behaviors by means of small diffusible chemical molecules.
Andrés Almozara +5 more
core +1 more source
Representing and analysing molecular and cellular function in the computer [PDF]
, 2000 Determining the biological function of a myriad of genes, and understanding how they interact to yield a living cell, is the major challenge of the post genome-sequencing era.
Eldridge, M +6 more
core +1 more source
Host-selected mutations converging on a global regulator drive an adaptive leap towards symbiosis in bacteria [PDF]
, 2017 Host immune and physical barriers protect against pathogens but also impede the establishment of essential symbiotic partnerships. To reveal mechanisms by which beneficial organisms adapt to circumvent host defenses, we experimentally evolved ...
Cooper, Vaughn S. +8 more
core +3 more sources
Evaluation of a new high-throughput method for identifying quorum quenching bacteria [PDF]
, 2013 Quorum sensing (QS) is a population-dependent mechanism for bacteria to synchronize social behaviors such as secretion of virulence factors. The enzymatic interruption of QS, termed quorum quenching (QQ), has been suggested as a promising alternative ...
Bossier, Peter +6 more
core +2 more sources
Discovery of new diketopiperazines inhibiting Burkholderia cenocepacia quorum sensing in vitro and in vivo [PDF]
, 2016 Burkholderia cenocepacia, an opportunistic respiratory pathogen particularly relevant for cystic fibrosis patients, is difficult to eradicate due to its high level of resistance to most clinically relevant antimicrobials.
Azzalin, Alberto +11 more
core +2 more sources
Rapid microwave-assisted CNBr cleavage of bead-bound peptides [PDF]
, 2008 Large libraries of peptides, cyclic peptides, and other molecules are standard tools for the discovery of drugs, molecular probes, and affinity reagents.
Cha, Junhoe +4 more
core +2 more sources
Engineering New‐to‐Nature Biological Pathways for β,γ‐Alkanediol Synthesis
Advanced Science, EarlyView.β,γ‐Alkanediols are value‐added chemicals to be used as functional solvents, biofuels, and cosmetic components. This work demonstrates a carboligation‐mediated approach for synthesis of linear chain β,γ‐alkanediols in Escherichia coli, namely, hexane‐2,3‐diol (2,3‐HDO) and pentane‐2,3‐diol (2,3‐PDO). The engineered E. coli cells produce 152.2 mm (17.98
Haofeng Chen +6 more
wiley +1 more source
Identifying Cytokine Motif‐Containing, Immunomodulatory Bacterial Proteins in Human Gut Microbiome
Advanced Science, EarlyView.By building and constructing HMM (Upper left, blue), the authors identify CMCPs in bacteria genomes and CRC related metagenomes and enriched CRC‐related CMCPs (Upper right, blue). They analyze sequence and structural similarity of hits (Lower left, green), test function with engineered EcN delivered to tumors in a mouse tumor model (Lower right, pink ...
Ziyu Wang +12 more
wiley +1 more source
Molecular Mechanisms of Algicidal Bacteria in Controlling Harmful Algal Blooms: Advances in Bacteria‐Algae Interactions [PDF]
Environ Microbiol RepThis review elucidates the molecular mechanisms of algicidal bacteria, highlighting critical behaviours like chemotaxis, quorum sensing and extracellular vesicle release. It details how these actions disrupt algal cellular integrity, photosynthesis and calcium homeostasis, providing a theoretical foundation for controlling harmful algal blooms ...
Wang J, Xu B, Huang L.
europepmc +2 more sources