Results 21 to 30 of about 17,772 (214)
One quorum sensing strain was isolated from spoiled turbot. The species was determined by 16S rRNA gene analysis and classical tests, named Aeromonas sobria AS7.
Tingting Li+4 more
doaj +1 more source
Quorum quenching (QQ) is a promising strategy for preventing and controlling quorum sensing (QS)-mediated bacterial infections. It interferes with QS by the inhibition of signal synthesis, the detection of enzyme-catalyzed degradation, and the ...
Xinghui Fan+11 more
doaj +1 more source
Homoserine Toxicity in Saccharomyces cerevisiae and Candida albicans Homoserine Kinase ( thr1 Δ) Mutants [PDF]
ABSTRACT In addition to threonine auxotrophy, mutation of the Saccharomyces cerevisiae threonine biosynthetic genes THR1 (encoding homoserine kinase) and THR4 (encoding threonine synthase) results in a plethora of other phenotypes.
John H. McCusker, Joanne M. Kingsbury
openaire +3 more sources
Methionine and threonine synthesis are limited by homoserine availability and not the activity of homoserine kinase in Arabidopsis thaliana [PDF]
SummaryHomoserine kinase (HSK) produces O‐phospho‐l‐homoserine (HserP) used by cystathionine γ‐synthase (CGS) for Met synthesis and threonine synthase (TS) for Thr synthesis. The effects of overexpressing Arabidopsis thaliana HSK, CGS, and Escherichia coli TS (eTS), each controlled by the 35S promoter, were compared.
Minsang Lee+5 more
openaire +3 more sources
Unlocking Lactonase Enzymes as Biocatalysts for the Deracemisation of Chiral γ‐Thiolactones
The application of lactonase enzymes as biocatalysts still remains underexplored. This study discloses the biocatalytic activity of two lactonases in the deracemisation of chiral C3‐substituted‐γ‐thiolactones. The biocatalyst GcL catalyses the enzymatic kinetic resolution (EKR) of C3‐amide‐thiolactones, while the rationally engineered biocatalyst N9 ...
Jingyue Wu+7 more
wiley +2 more sources
Quorum Sensing Activity in Pandoraea pnomenusa RB38
Strain RB38 was recovered from a former dumping area in Malaysia. MALDI-TOF mass spectrometry and genomic analysis identified strain RB-38 as Pandoraea pnomenusa. Various biosensors confirmed its quorum sensing properties.
Robson Ee+4 more
doaj +1 more source
Quorum sensing (QS) is a cell density-dependent mechanism that regulates the expression of specific genes in microbial cells. Quorum quenching (QQ) is a promising strategy for attenuating pathogenicity by interfering with the QS system of pathogens.
Wenping Zhang+8 more
doaj +1 more source
X-box binding protein 1 (XBP1s) is a critical determinant of Pseudomonas aeruginosa homoserine lactone-mediated apoptosis. [PDF]
Pseudomonas aeruginosa infections are associated with high mortality rates and occur in diverse conditions including pneumonias, cystic fibrosis and neutropenia.
Cathleen D Valentine+3 more
doaj +1 more source
Quorum quenching (QQ) is a novel, promising strategy that opens up a new perspective for controlling quorum-sensing (QS)-mediated bacterial pathogens.
Wenping Zhang+13 more
doaj +1 more source
Bacteria need to be isolated in pure culture to gain access to the wide array of interesting functions they conceal. This is challenging because they do not live in isolation but instead in communities where they actively communicate and interact with ...
Marco A. Lopez Marin+2 more
doaj +1 more source