Pyoverdine and proteases affect the response of pseudomonas aeruginosa to gallium in human serum [PDF]
Gallium is an iron mimetic which has recently been repurposed as an antibacterial agent due to its capability to disrupt bacterial iron metabolism. In this study, the antibacterial activity of gallium nitrate [Ga(NO3)3] was investigated in complement ...
Bonchi, Carlo +3 more
core +1 more source
ABSTRACT Background Pseudomonas aeruginosa is an opportunistic pathogen in cystic fibrosis‐related chronic rhinosinusitis (CF‐CRS) that produces phenazine metabolites pyocyanin and 1‐hydroxyphenazine (1‐HP), which may have detrimental effects on mitochondria, reactive oxygen species (ROS), Ca2+ signaling, and apoptosis.
Joel C. Thompson +8 more
wiley +1 more source
Phenazine‐Based Synthetic Biology to Signal Between Cells and Electrodes
ABSTRACT Bioelectronic systems that enable seamless communication between electronic devices and living systems represent a transformative frontier in biotechnology. Among available methodologies, redox based signaling offers unique advantages due to its ubiquity in biology and compatibility with standard electrochemical equipment, expanding on ...
Eric VanArsdale +8 more
wiley +1 more source
Identification of small RNAs abundant in Burkholderia cenocepacia biofilms reveal putative regulators with a potential role in carbon and iron metabolism [PDF]
Small RNAs play a regulatory role in many central metabolic processes of bacteria, as well as in developmental processes such as biofilm formation. Small RNAs of Burkholderia cenocepacia, an opportunistic pathogenic beta-proteobacterium, are to date not ...
Coenye, Tom +2 more
core +3 more sources
One‐step, highly efficient, and scalable synthesis of acp3U phosphoramidite is described, as well as a new alternative synthesis of cmnm5U phosphoramidite from a highly versatile intermediate. Latter could be scaled‐up, split, and aliquots turned simultaneously into cmnm5U, nm5U, and mnm5U.
Ewa Mejdr +3 more
wiley +1 more source
The synthesis of an analogue of the locust CRF-like diuretic peptide, and the biological activities of this and some C-terminal fragments. [PDF]
The synthesis is described of an analogue of the locust CRF-like diuretic peptide in which methionine in positions 1,3, and 13 is replaced by isosteric methyl-homoserine residues.
Audsley +19 more
core +1 more source
The Curious Case of CysE: Diversity and Distribution of Serine Acetyltransferases in Bacteria
ABSTRACT Serine acetyltransferase (CysE) is a member of the left‐handed β‐helix family of acetyltransferases that catalyze the rate limiting step in de novo cysteine biosynthesis. There are two isoforms of CysE that differ in length, with the shorter isoform lacking approximately 76 amino acids at the N‐terminus of the protein from the serine ...
Keely E. A. Oldham +3 more
wiley +1 more source
Induction of diverse secondary metabolites in Aspergillus fumigatus by microbial co-culture [PDF]
Peer reviewedPublisher ...
Abraham +38 more
core +1 more source
Draft genome of Neofabraea vagabunda, the agent of bull's eye rot
Circular representation of the 12 major scaffolds from the draft genome of Neofabraea vagabunda showing gene density, density of repeated regions, GC content, and functional features (secrete and membrane proteins, proteases, and CAZymes) distribution.
Saveria Mosca +4 more
wiley +1 more source
Screening of Indonesia Medicinal Plants Producing Quorum Sensing Inhibitor [PDF]
Antibiotic resistance of bacteria lead to create different way in the pathogen bacteria handling such us inhibit their quorum sensing mechanism. The goal of this study is to search quorum sensing inhibitor of seven Indonesia medicinal plants.
Artadana, Ida Bagus Made +7 more
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