Results 41 to 50 of about 24,736 (258)

Methionine and threonine synthesis are limited by homoserine availability and not the activity of homoserine kinase in Arabidopsis thaliana [PDF]

open access: yesThe Plant Journal, 2005
SummaryHomoserine kinase (HSK) produces O‐phospho‐l‐homoserine (HserP) used by cystathionine γ‐synthase (CGS) for Met synthesis and threonine synthase (TS) for Thr synthesis. The effects of overexpressing Arabidopsis thaliana HSK, CGS, and Escherichia coli TS (eTS), each controlled by the 35S promoter, were compared.
Minsang Lee   +5 more
openaire   +3 more sources

Exploration of the Quorum-Quenching Mechanism in Pseudomonas nitroreducens W-7 and Its Potential to Attenuate the Virulence of Dickeya zeae EC1

open access: yesFrontiers in Microbiology, 2021
Quorum quenching (QQ) is a novel, promising strategy that opens up a new perspective for controlling quorum-sensing (QS)-mediated bacterial pathogens.
Wenping Zhang   +13 more
doaj   +1 more source

N-Acyl homoserine lactone analog modulators of the Pseudomonas aeruginosa RhlI quorum sensing signal synthase.

open access: yesACS Chemical Biology, 2019
Virulence in the Gram-negative pathogen Pseudomonas aeruginosa relies in part on the efficient functioning of two LuxI/R dependent quorum sensing (QS) cascades, namely the LasI/R and RhlI/R systems that generate and respond to N-(3-oxo)-dodecanoyl-L ...
Daniel Shin   +7 more
semanticscholar   +1 more source

Joining the bacterial conversation: increasing the cultivation efficiency of soil bacteria with acyl-homoserine lactones and cAMP

open access: yesMicrobiology Spectrum, 2023
Bacteria need to be isolated in pure culture to gain access to the wide array of interesting functions they conceal. This is challenging because they do not live in isolation but instead in communities where they actively communicate and interact with ...
Marco A. Lopez Marin   +2 more
doaj   +1 more source

Quorum Sensing Activity of Mesorhizobium sp. F7 Isolated from Potable Water

open access: yesThe Scientific World Journal, 2014
We isolated a bacterial isolate (F7) from potable water. The strain was identified as Mesorhizobium sp. by 16S rDNA gene phylogenetic analysis and screened for N-acyl homoserine lactone (AHL) production by an AHL biosensor. The AHL profile of the isolate
Pei-Ling Yong, Kok-Gan Chan
doaj   +1 more source

Quorum Sensing Activity of Enterobacter asburiae Isolated from Lettuce Leaves

open access: yesSensors, 2013
Bacterial communication or quorum sensing (QS) is achieved via sensing of QS signaling molecules consisting of oligopeptides in Gram-positive bacteria and N-acyl homoserine lactones (AHL) in most Gram-negative bacteria.
Kok-Gan Chan   +4 more
doaj   +1 more source

Homoserine and quorum‐sensing acyl homoserine lactones as alternative sources of threonine: a potential role for homoserine kinase in insect‐stage Trypanosoma brucei

open access: yesMolecular Microbiology, 2014
SummaryDe novo synthesis of threonine from aspartate occurs via the β‐aspartyl phosphate pathway in plants, bacteria and fungi. However, the Trypanosoma brucei genome encodes only the last two steps in this pathway: homoserine kinase (HSK) and threonine synthase.
Ong, Han B.   +4 more
openaire   +4 more sources

The Role of Transamination in the Synthesis of Homoserine in Peas [PDF]

open access: yesPlant Physiology, 1986
Incubation of intact pea plants (Pisum sativum), or detached shoots, in continuous light caused a substantial increase (up to 4-fold in 2 days) in levels of homoserine. Amino acids supplied to leaves in the transpiration stream enhanced the accumulation, with glutamate, aspartate, and asparagine causing similar enhancement.
Kenneth W. Joy, Chander Prabha
openaire   +3 more sources

Durable Bio‐Based Nanocomposite Coating on Urinary Catheters Prevents Early‐Stage CAUTI‐Associated Pathogenicity

open access: yesAdvanced Materials Interfaces, EarlyView.
A stable bio‐based nanocomposite coating for urinary catheters is developed using a simple, environmentally‐friendly sonochemical process. The coating, integrating antimicrobial, antibiofilm, and antioxidant properties, effectively tackled multiple early‐stage pathogenic factors associated with catheter‐associated urinary tract infections.
Antonio Puertas‐Segura   +7 more
wiley   +1 more source

The crystal structure of homoserine dehydrogenase complexed withl-homoserine and NADPH in a closed form

open access: yesThe Journal of Biochemistry, 2018
Homoserine dehydrogenase from Thermus thermophilus (TtHSD) is a key enzyme in the aspartate pathway that catalyses the reversible conversion of l-aspartate-β-semialdehyde to l-homoserine (l-Hse) with NAD(P)H. We determined the crystal structures of unliganded TtHSD, TtHSD complexed with l-Hse and NADPH, and Lys99Ala and Lys195Ala mutant TtHSDs, which ...
Shota Akai   +5 more
openaire   +2 more sources

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