Results 41 to 50 of about 46,167 (302)

Representing and analysing molecular and cellular function in the computer [PDF]

, 2000
Determining the biological function of a myriad of genes, and understanding how they interact to yield a living cell, is the major challenge of the post genome-sequencing era.
Eldridge, M, Gilbert, D, Helden, JV, Mancuso, R, Naim, A, Wernisch, L, Wodak, SJ   +6 more
core   +1 more source

Effect of efflux pump inhibition on Pseudomonas aeruginosa transcriptome and virulence [PDF]

, 2017
Efflux pumps of the resistance-nodulation-cell-division (RND) family increase antibiotic resistance in many bacterial pathogens, representing candidate targets for the development of antibiotic adjuvants.
Baldelli, Valerio, Bondã¬, Roslen, Imperi, Francesco, Leoni, Livia, Longo, Francesca, Messina, Marco, Pillai, Cejoice Ramachandran, Rampioni, Giordano, Visca, Paolo   +8 more
core   +2 more sources

Involvement of Acylated Homoserine Lactones (AHLs) of Aeromonas sobria in Spoilage of Refrigerated Turbot (Scophthalmus maximus L.)

Sensors, 2016
One quorum sensing strain was isolated from spoiled turbot. The species was determined by 16S rRNA gene analysis and classical tests, named Aeromonas sobria AS7.
Tingting Li, Fangchao Cui, Fengling Bai, Guohua Zhao, Jianrong Li   +4 more
doaj   +1 more source

Potential of a Quorum Quenching Bacteria Isolate Ochrobactrum intermedium D-2 Against Soft Rot Pathogen Pectobacterium carotovorum subsp. carotovorum

Frontiers in Microbiology, 2020
Quorum quenching (QQ) is a promising strategy for preventing and controlling quorum sensing (QS)-mediated bacterial infections. It interferes with QS by the inhibition of signal synthesis, the detection of enzyme-catalyzed degradation, and the ...
Xinghui Fan, Xinghui Fan, Tian Ye, Tian Ye, Qiting Li, Qiting Li, Pankaj Bhatt, Pankaj Bhatt, Lianhui Zhang, Lianhui Zhang, Shaohua Chen, Shaohua Chen   +11 more
doaj   +1 more source

Host-selected mutations converging on a global regulator drive an adaptive leap towards symbiosis in bacteria [PDF]

, 2017
Host immune and physical barriers protect against pathogens but also impede the establishment of essential symbiotic partnerships. To reveal mechanisms by which beneficial organisms adapt to circumvent host defenses, we experimentally evolved ...
Cooper, Vaughn S., Coyle, Matthew, Donner, Rachel A., Foxall, Randi L., Pankey, Molly Sabrina, Perry, Lauren A., Schuster, Brian M., Ster, Ian M., Whistler, Cheryl A.   +8 more
core   +3 more sources

Quorum Sensing Activity in Pandoraea pnomenusa RB38

Sensors, 2014
Strain RB38 was recovered from a former dumping area in Malaysia. MALDI-TOF mass spectrometry and genomic analysis identified strain RB-38 as Pandoraea pnomenusa. Various biosensors confirmed its quorum sensing properties.
Robson Ee, Yan-Lue Lim, Lin-Xin Kin, Wai-Fong Yin, Kok-Gan Chan   +4 more
doaj   +1 more source

Quorum Quenching in a Novel Acinetobacter sp. XN-10 Bacterial Strain against Pectobacterium carotovorum subsp. carotovorum

Microorganisms, 2020
Quorum sensing (QS) is a cell density-dependent mechanism that regulates the expression of specific genes in microbial cells. Quorum quenching (QQ) is a promising strategy for attenuating pathogenicity by interfering with the QS system of pathogens.
Wenping Zhang, Qingqing Luo, Yiyin Zhang, Xinghui Fan, Tian Ye, Sandhya Mishra, Pankaj Bhatt, Lianhui Zhang, Shaohua Chen   +8 more
doaj   +1 more source

Structure, substrate recognition and reactivity of Leishmania major mevalonate kinase [PDF]

, 2007
This research was supported by the German Academic Exchange Service (DAAD), the Wellcome Trust (TKS and WNH as Trust Senior Research fellows), the Biotechnology and Biological Science Research Council (Structural Proteomics of Rational Targets) and the ...
Hunter, William N., Sgraja, Tanja, Smith, Terry K   +2 more
core   +2 more sources

Biofilms, homoserine lactones and biocide susceptibility [PDF]

Journal of Antimicrobial Chemotherapy, 2004
To investigate the susceptibility, to a range of different biocides, of Pseudomonas aeruginosa strains variously deficient in N-acyl homoserine lactone systems, grown either as planktonic or biofilm populations.Biocide susceptibility data were generated for strains of P. aeruginosa deficient in N-acyl homoserine lactone production, grown planktonically
MacLehose, Harriet G., Gilbert, Peter, Allison, David G.   +2 more
openaire   +4 more sources

Exploration of the Quorum-Quenching Mechanism in Pseudomonas nitroreducens W-7 and Its Potential to Attenuate the Virulence of Dickeya zeae EC1

Frontiers in Microbiology, 2021
Quorum quenching (QQ) is a novel, promising strategy that opens up a new perspective for controlling quorum-sensing (QS)-mediated bacterial pathogens.
Wenping Zhang, Wenping Zhang, Xinghui Fan, Xinghui Fan, Jiayi Li, Jiayi Li, Tian Ye, Tian Ye, Sandhya Mishra, Sandhya Mishra, Lianhui Zhang, Lianhui Zhang, Shaohua Chen, Shaohua Chen   +13 more
doaj   +1 more source