Results 91 to 100 of about 6,623 (164)

Lomitapide in homozygous familial hypercholesterolemia: cardiology perspective from a single-center experience

, 2018
AIMS: Homozygous familial hypercholesterolemia (HoFH) is a genetic dyslipidemia characterized by elevated levels of low-density lipoprotein cholesterol (LDL-C) and accelerated atherosclerosis.
Gragnano F, Sperlongano, Rossella, Russo, Maria giovanna, Marcello Arca, Arca M, D'Erasmo L, D'Erasmo, Laura, Calabrò P, Gragnano, Felice, Golia E, Giuseppe Limongelli, Russo M, Mario Crisci, Laura D’Erasmo, Natale F, Enrica Golia, Natale, Francesco, Concilio C, Simona Sperlongano, Rossella Sperlongano, Fabio Fimiani, Calabrò, Paolo, Limongelli G, Arca, Marcello, Cesaro A, Fimiani, Fabio, Cesaro, Arturo, Crisci M, Crisci, Mario, Golia, Enrica, Paolo Calabrò, Sperlongano R, Mariagiovanna Russo, Sperlongano S, Arturo Cesaro, Fimiani F, Claudia Concilio, Francesco Natale, Limongelli, Giuseppe, Concilio, Claudia, Sperlongano, Simona, Felice Gragnano   +41 more
core   +1 more source

A Real-World Experience of Clinical, Biochemical and Genetic Assessment of Patients with Homozygous Familial Hypercholesterolemia

, 2020
Homozygous familial hypercholesterolemia (HoFH), the severest form of familial hypercholesterolemia (FH), is characterized by very high LDL-cholesterol levels and a high frequency of coronary heart disease. The disease is caused by the presence of either
Fortunato, Giuliana, Paolo Rubba, Giovanna Maione, Ilenia Calcaterra, Giuliana Fortunato, Calcaterra, Ilenia, Giacobbe, Carola, Carola Giacobbe, Maria Donata Di Taranto, Palma, Daniela, Maione, Giovanna, Iannuzzo, Gabriella, Di Taranto, Maria Donata, Buonaiuto, Alessio, Gabriella Iannuzzo, Matteo Nicola Dario Di Minno, Di Minno, Matteo Nicola Dario, Alessio Buonaiuto, Daniela Palma, Rubba, Paolo   +19 more
core   +1 more source

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Homozygous familial hypercholesterolemia with stenosis of the left anterior descending coronary artery successfully treated with weekly low‐density lipoprotein apheresis for 16 years without percutaneous coronary intervention

Clinical Case Reports, 2019
We successfully treated a patient with homozygous familial hypercholesterolemia (HoFH) with stable coronary arterial disease using optimal medical therapy and low‐density lipoprotein (LDL) apheresis for 16 years without percutaneous coronary intervention
Takanori Yasu, Masahiro Shimoyama, Hiroshi Wada, Tomohiro Iwakura, Shigeru Toyoda, Atsuhiko Kawabe, Takushi Sugiyama   +6 more
doaj   +1 more source

Publication Only

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Liver transplantation in severe and homozygous familial hypercholesterolemia - a scoping review

The purpose of this scoping review will be to examine the existing literature surrounding liver transplantation in patients with homozygous familial hypercholesterolemia (hoFH)
Erin Kelty, Jing Pang
core   +1 more source

Usefulness of Gemcabene in Homozygous Familial Hypercholesterolemia (from COBALT-1)

, 2019
Homozygous familial hypercholesterolemia (HoFH) is a rare genetic disorder characterized by severely elevated plasma low-density lipoprotein-cholesterol (LDL-C), and premature atherosclerotic cardiovascular disease.
Durst, Ronen, Masson, Liz, Gaudet, Daniel, Stein, Evan, Lepor, Norman, Bakker-Arkema, Rebecca, Hegele, Robert A., Bisgaier, Charles, Kastelein, John J., Golden, Lee   +9 more
core   +1 more source

Mipomersen and other therapies for the treatment of severe familial hypercholesterolemia

Vascular Health and Risk Management, 2012
Damon A Bell,1–3 Amanda J Hooper,1,2,4 Gerald F Watts,2,3 John R Burnett1–41Department of Core Clinical Pathology and Biochemistry, PathWest Laboratory Medicine, 2School of Medicine and Pharmacology, 3Lipid Disorders Clinic ...
Bell DA, Hooper AJ, Watts GF, Burnett JR
doaj  

Coronary artery bypass grafting in a 14-year-old boy with compound heterozygous LDLR familial hypercholesterolemia: a case report

Frontiers in Pediatrics
Familial hypercholesterolemia (FH), particularly homozygous or compound heterozygous forms, predisposes individuals to premature cardiovascular disease due to severely elevated low-density lipoprotein cholesterol (LDL-C).
Ke Zhu, Fuqiang Zhang, Jin Wang, Chunjing Li   +3 more
doaj   +1 more source

Breaking barriers: Innovative therapies for managing homozygous familial hypercholesterolemia

Experimental and Molecular Pathology
Homozygous familial hypercholesterolemia (HoFH) is a rare autosomal recessive disorder characterized by variants in genes involved in the regulation of low-density lipoprotein cholesterol (LDL-C) metabolism.
Shuai-Jie Huang, Ping Huang, Nan-Nan Song, Xian-Hui Jia, Hong-Li Gao, Zhi-Yuan Lu, Xiao-Lan Wen   +6 more
doaj   +1 more source