Results 81 to 90 of about 286,443 (160)

Correlation between clinical classification and genetic analysis of familial hypercholesterolemia in premature coronary artery disease in a cohort of Egyptian patients

Human Genomics
Background Familial Hypercholesterolemia (FH) is a major risk factor for premature Coronary Artery Disease (CAD). Genetic testing is the gold standard for FH diagnosis.
Rania A. Zahwo, Ziad N. Rezk, Tamer M. Elwasify, Amr M. Zaki, Hoda M. El Assi, Eman Ramadan, Abdallah Y. Habib, Wael A. Hassan, Ahmed Abdel-Raouf, Ameera Ragheb, Amin F. Shaker, Khaled E. Amer, Heba Sh. Kassem   +12 more
doaj   +1 more source

From Disease Silos to Integrated Cardiometabolic Care: Diabetes, Vascular Disease, and Heart Failure

Journal of Diabetes, Volume 18, Issue 9, September 2026.
Zachary T. Bloomgarden, Yehuda Handelsman   +1 more
wiley   +1 more source

"Therapy with Lomitapide in Homozygous Familial Hypercholesterolemia"

, 2022
reservedBACKGROUND: l’ipercolesterolemia familiare omozigote (HoFH) è una patologia rara, pericolosa per la vita, caratterizzata da livelli molto elevati di colesterolo LDL e da malattia aterosclerotica cardiovascolare (ACVD) precoce e in rapida ...
TOSIN, PAOLA
core  

Would raising the total cholesterol diagnostic cut-off from 7.5 mmol/L to 9.3 mmol/L improve detection rate of patients with monogenic familial hypercholesterolaemia? [PDF]

, 2015
A previous report suggested that 88% of individuals in the general population with total cholesterol (TC) > 9.3 mmol/L have familial hypercholesterolaemia (FH). We tested this hypothesis in a cohort of 4896 UK civil servants, mean (SD) age 44 (±6) years,
Humphries, S.E., Kivimaki, M, Boustred, C, Boustred, C., Kumari, M., Kivimaki, M., Humphries, SE, Futema, M., Futema, M, Kumari, M   +9 more
core   +1 more source

A Scoping Review of Electronic Health Records–Based Screening Algorithms for Familial Hypercholesterolemia [PDF]

BackgroundFamilial hypercholesterolemia (FH) is a common genetic disorder that is strongly associated with premature cardiovascular disease. Effective diagnosis and appropriate treatment of FH can reduce cardiovascular disease risk; however, FH is ...
Khoury, Muin J., Otchere, Baffour, Osei, Jeffery, Coronado, Fatima, Akyea, Ralph K., Bonful, Gracelove, Razavi, Alexander C., Akoto, Natalie, Kolor, Katherine, Mensah, George A., Sperling, Laurence, Moonesinghe, Ramal, Qureshi, Nadeem   +12 more
core   +1 more source

Liver transplantation in a subject with familial hypercholesterolemia carrying the homozygous p.W577R LDL-receptor gene mutation

, 2007
Mutations within the low density lipoprotein (LDL)-receptor gene result in familial hypercholesterolemia, an autosomal dominant inherited disease.
Oldhafer, Karl, Jürgen Klempnauer, Buettner, Janine, Hannelore Barg-Hock, Schmidt, Hartmut H-J., Uwe J.F. Tietge, Kallfelz, Hans C., Dedoussis, Giorgos V., Rodeck, Burkhard, Tietge, Uwe J.F., Gisela Offner, Giorgos V. Dedoussis, Burkhard Rodeck, Klempnauer, Jürgen, Hartmut H-J. Schmidt, Schmidt, Hartmut H‐J., Schweitzer, Susanne, Janine Buettner, Schlitt, Hans‐Jürgen, Schlitt, Hans-Juergen, Barg‐Hock, Hannelore, Offner, Gisela, Hans-Jürgen Schlitt, Hans C. Kallfelz, Tietge, Uwe J. F., Klempnauer, Juergen, Susanne Schweitzer, Karl Oldhafer, Barg-Hock, Hannelore   +28 more
core   +1 more source

Clinical Evaluation Of Evolocumab For The Treatment Of Homozygous Familial Hypercholesterolemia In Chinese Patients

, 2019
Chin-Chou Huang,1–5 Min-Ji Charng2,3 1Department of Medical Education, Taipei Veterans General Hospital, Taipei, Taiwan; 2Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan; 3Faculty of Medicine, School
Huang CC, Charng MJ
core  

Abstracts

Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Left main coronary angioplasty in a 10-year-old boy with homozygous familial hypercholesterolemia.

, 1993
Homozygous familial hypercholesterolemia is a rare cause of premature coronary artery disease. A young boy with this disorder who underwent successful coronary angioplasty for left main stem stenosis is ...
Stocker FP, Meier B, Pfammatter JP, Mehan VK, Salzmann C   +4 more
core   +1 more source

Homozygous familial hypercholesterolemia with stenosis of the left anterior descending coronary artery successfully treated with weekly low‐density lipoprotein apheresis for 16 years without percutaneous coronary intervention

Clinical Case Reports, 2019
We successfully treated a patient with homozygous familial hypercholesterolemia (HoFH) with stable coronary arterial disease using optimal medical therapy and low‐density lipoprotein (LDL) apheresis for 16 years without percutaneous coronary intervention
Takanori Yasu, Masahiro Shimoyama, Hiroshi Wada, Tomohiro Iwakura, Shigeru Toyoda, Atsuhiko Kawabe, Takushi Sugiyama   +6 more
doaj   +1 more source