Results 81 to 90 of about 6,623 (164)

Clinical outcome of patients with familial hypercholesterolemia and coronary artery disease undergoing partial ileal bypass surgery

Arquivos Brasileiros de Cardiologia, 2000
Familial hypercholesterolemia is characterized by high serum levels of total cholesterol and LDL-cholesterol. It may be homozygous or heterozygous. In homozygous patients, LDL-cholesterol levels range from 500 to 1000mg/dL and coronary artery disease is ...
Jaqueline Scholz Issa, Artur Garrido Jr, Sérgio Diogo Giannini, Neusa Forti, Jayme Diament, Henrique Walter Pinotti   +5 more
doaj   +1 more source

Homozygous familial hypercholesterolemia

, 2014
We report a rare case of homozygous familial hypercholesterolemia (HoFH), a 22-year-old Malay woman who presented initially with minor soft tissue injury due to a cycling accident.
Siti Ayuni Binti Zakyudin
core  

The effect of lomitapide on cardiovascular outcome measures in homozygous familial hypercholesterolemia: A modelling analysis

, 2017
Background Patients with homozygous familial hypercholesterolemia are at high risk of cardiovascular disease due to high low-density lipoprotein (LDL)-cholesterol levels. Cardiovascular disease outcome studies are impossible to conduct, due to the rarity
Leipold, Robert, Ishak, Jack, Phillips, Helen, Raal, Frederick, Hovingh, Kees   +4 more
core   +1 more source

Clinical and molecular characteristics of homozygous familial hypercholesterolemia patients: Insights from SAFEHEART registry [PDF]

, 2016
Homozygous familial hypercholesterolemia (HoFH) is a rare genetic disorder associated with very high levels of cholesterol, accelerated atherosclerosis and very premature death, often secondary to occlusion of the coronary ostia by supravalvular atheroma
Saenz, Pedro, Mata, Pedro, Arrieta, Francisco, Rodriguez-Urrego, Johana, Alonso, Rodrigo, Fuentes-Jiménez, Francisco, Miramontes, José P, Díaz-Díaz, Jose Luis, Argueso, Rosa, de Andrés, Raimundo, Perez de Isla, Leopoldo, Pintó, Xavier, Vidal-Pardo, José I, Prieto Matos, Pablo, Almagro, Fatima, Ariceta, Gema   +15 more
core   +1 more source

Life Course Approach for Managing Familial Hypercholesterolemia

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Treatment of familial hypercholesterolemia is directed toward the moment of the medical encounter. However, risk for heart disease as a consequence of having familial hypercholesterolemia is related to lifelong exposure to elevated low‐density ...
Samuel S. Gidding, Dirk J. Blom, Brian McCrindle, Uma Ramaswami, Raul D. Santos, Gerald F. Watts, Albert Wiegman   +6 more
doaj   +1 more source

Correlation between clinical classification and genetic analysis of familial hypercholesterolemia in premature coronary artery disease in a cohort of Egyptian patients

Human Genomics
Background Familial Hypercholesterolemia (FH) is a major risk factor for premature Coronary Artery Disease (CAD). Genetic testing is the gold standard for FH diagnosis.
Rania A. Zahwo, Ziad N. Rezk, Tamer M. Elwasify, Amr M. Zaki, Hoda M. El Assi, Eman Ramadan, Abdallah Y. Habib, Wael A. Hassan, Ahmed Abdel-Raouf, Ameera Ragheb, Amin F. Shaker, Khaled E. Amer, Heba Sh. Kassem   +12 more
doaj   +1 more source

Apheresis-inducible cytokine pattern change in children with homozygous familial hypercholesterolemia

, 2013
Familial hypercholesterolemia is a genetic disorder that leads to severe atherosclerosis related cardiovascular complications in young adults. Extracorporeal elimination is a method of LDL-lowering procedures effective in patients with homozygous or ...
TÜMER, LEYLA, Kasapkara, ÇİĞDEM SEHER, Hasanoglu, Alev, Demirtas, CANAN, ÇELİK, BÜLENT, Dilsiz, Gunter, Pasaoglu, Ozge, EZGÜ, FATİH SÜHEYL, Yenicesu, Idil, Kucukcongar, Aynur   +9 more
core   +1 more source

Clinical Evaluation Of Evolocumab For The Treatment Of Homozygous Familial Hypercholesterolemia In Chinese Patients

, 2019
Chin-Chou Huang,1–5 Min-Ji Charng2,3 1Department of Medical Education, Taipei Veterans General Hospital, Taipei, Taiwan; 2Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan; 3Faculty of Medicine, School
Huang CC, Charng MJ
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Multidetector CT of the coronary arteries and aortic root in a pediatric patient with homozygous familial hypercholesterolemia – correlation with invasive coronary angiography

, 2005
Sixteen slice multidetector cardiac CT findings of a homozygous familial hypercholesterolemia pediatric patient are presented. Multidetector cardiac CT followed by invasive coronary angiography depicted a variety of diagnostic findings involving the ...
Engel, Ahuva, Lessick, Jonathan, Dragu, Robert, Ofer, Amos, Litmanovich, Diana, Rispler, Shmuel, Lorber, Avraham, Ghersin, Eduard   +7 more
core   +1 more source

Premature Valvular Heart Disease in Homozygous Familial Hypercholesterolemia [PDF]

, 2017
Valvular heart disease frequently occurs as a consequence of premature atherosclerosis in individuals with familial hypercholesterolemia (FH). Studies have primarily focused on aortic valve calcification in heterozygous FH, but there is paucity of data ...
Fadi F. Bitar, Mariam T. Arabi, Nemer, Georges M., Andary, Rabih R., Fady F. Haddad, Haddad, Fady F., Nguyen, Denis D., Sami T. Azar, Arabi, Mariam Toufic, Fahed, Akl C., Robert H. Habib, Denis D. Nguyen, Elie Moubarak, Moubarak, Elie M., Rabih R. Andary, Shibbani, Kamel, Kamel Shibbani, Georges Nemer, Habib, Robert H., Bitar, Fadi Fouad, Akl C. Fahed, Azar, Sami T.   +21 more
core   +1 more source