Results 71 to 80 of about 286,443 (160)
Homozygous Familial Hypercholesterolemia: Anesthetic Challenges and Review of Literature
, 2017 Homozygous familial hypercholesterolemia (HoFH; Fredrickson IIa) is a rare autosomal dominant hereditary disease associated with increased low-density lipoprotein cholesterol.
Sudheer K Aarav +3 more
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Treatment of Familial Hypercholesterolemia
, 2018 Familial hypercholesterolemia is the most prevalent genetic disorder with a autosomal dominant background. Early detection of the condition is important, diagnosing the disease is easily missed in most of the cases until some abnormally early CVD ...
Alharshani, Bushra Farhan M
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The genetics of familial hypercholesterolemia and emerging therapies
, 2015 Anja Vogt Medizinische Klinik und Poliklinik IV, Klinikum der Unversität München, Munich, Germany Abstract: Familial hypercholesterolemia (FH) results in very high levels of atherogenic low-density lipoprotein (LDL) cholesterol from the time ...
Vogt A
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Advances in Lipid-Lowering Therapy for Homozygous Familial Hypercholesterolemia
罕见病研究Homozygous familial hypercholesterolemia (HoFH) is an extremely rare and severe hereditary lipid metabolism disorder, characterized by markedly elevated levels of plasma low-density lipoprotein cholesterol (LDL-C), significantly increasing the risk of ...
LI Rui, TIAN Zhuang, ZHANG Shuyang
doaj +1 more source
Characteristic cardiovascular manifestation in homozygous and heterozygous familial hypercholesterolemia [PDF]
, 1999 Background The aortic valve dysfunction of patients with homozygous familial hypercholesterolemia (FH) suggests that hypercholesterolemia affects not only coronary arteries, but also the aortic valve.
Yutani, Chikao +6 more
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New Frontiers in the Treatment of Homozygous Familial Hypercholesterolemia
, 2022 Homozygous familial hypercholesterolemia (HoFH) is a rare genetic disorder. The most common cause is a mutation in both alleles of the gene encoding for the low-density lipoprotein (LDL) receptor, although other causative mutations have been identified ...
Schiavo A. +12 more
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Homozygous familial hypercholesterolemia
, 2014 We report a rare case of homozygous familial hypercholesterolemia (HoFH), a 22-year-old Malay woman who presented initially with minor soft tissue injury due to a cycling accident.
Siti Ayuni Binti Zakyudin
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Lomitapide: a novel drug for homozygous familial hypercholesterolemia [PDF]
, 2014 Lomitapide (Juxtapid® and Lojuxta®; Aegerion Pharmaceuticals, Inc., MA, USA), an orally administered inhibitor of the microsomal triglyceride transfer protein, inhibits the synthesis and secretion of ApoB-containing lipoproteins and, thus, reduces plasma
AVERNA, Maurizio +2 more
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Life Course Approach for Managing Familial Hypercholesterolemia
Journal of the American Heart Association: Cardiovascular and Cerebrovascular DiseaseTreatment of familial hypercholesterolemia is directed toward the moment of the medical encounter. However, risk for heart disease as a consequence of having familial hypercholesterolemia is related to lifelong exposure to elevated low‐density ...
Samuel S. Gidding +6 more
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Arquivos Brasileiros de Cardiologia, 2000 Familial hypercholesterolemia is characterized by high serum levels of total cholesterol and LDL-cholesterol. It may be homozygous or heterozygous. In homozygous patients, LDL-cholesterol levels range from 500 to 1000mg/dL and coronary artery disease is ...
Jaqueline Scholz Issa +5 more
doaj +1 more source