Results 191 to 200 of about 142,071 (297)

Research progress on protein tyrosine phosphatase A from Mycobacterium tuberculosis. [PDF]

Front Immunol
Cai Y, Zhang L.
europepmc   +1 more source

The Transcription Factor FgSge1 Harnesses the SAGA Complex to Activate Mycotoxin Biosynthesis and Fungal Virulence

Advanced Science, EarlyView.
This study reveals the molecular mechanism by which the transcription factor FgSge1 regulates mycotoxin biosynthesis and virulence in Fusarium graminearum. FgSge1 binds to the TAARGTTT cis‐element, enabling self‐activation. It recruits the SAGA complex, promotes histone acetylation, and facilitates jet‐like chromatin remodeling, thereby activating ...
Yueqi Zhang, Jingrui Wang, Qiaowan Chen, Chen Jiao, Yun Chen, Zhongshou Wu, Zhonghua Ma   +6 more
wiley   +1 more source

Yield Performance and Phytochemical Stability of 'Comet' Hop Under Contrasting Light Supplementation Regimes in Subtropical Conditions. [PDF]

Plants (Basel)
Neves CS, Bonfim FPG, Campos OP, Viriato V, Fernandes GDC, Cabral MNF, Fortuna GC, Gonçalves de Oliveira S, Rabinowitz AN, Sarnighausen VCR, Ono EO, Silva JCRL, Marques MOM.   +12 more
europepmc   +1 more source

Synergistic Tuning of Conformational Dynamics, Electron Tunneling, and Substrate Positioning Enhances Electron Transfer in a P450 Chimera for Calcifediol Biosynthesis

Advanced Science, EarlyView.
A synergistic electron transfer (ET) optimization strategy modulating conformational dynamics, ET pathway, and substrate orientation is proposed for self‐sufficient cytochrome P450s. Guided by this strategy, a P450 variant with improved ET and catalytic efficiency was identified, and the underlying molecular basis was revealed by computational analysis.
Ziqi Liang, Xitong Song, Shuming Cheng, Yiwen Shen, Jie Zhang, Yaru Wang, Huiying Luo, Bin Yao, Binju Wang, Tao Tu   +9 more
wiley   +1 more source

6-Prenylnaringenin-Its Beneficial Biological Effects and Possible Applications. [PDF]

Int J Mol Sci
Tronina T, Łój D, Popłoński J, Bartmańska A.   +3 more
europepmc   +1 more source

Why Computational Photochemistry Is Challenging and Will Probably Remain So: A Quantum Chemist's Perspective

Advanced Science, EarlyView.
Computational Photochemistry has made great strides in recent decades, but the investigation of larger molecules remains a challenge due to the inherent dilemma between the increasing computational accuracy required as the molecule size increases and the inevitable explosion in computational effort.
Andreas Dreuw
wiley   +1 more source

Effects of three strength training methods on lower extremity strength, jump and sprint performance: a network meta-analysis. [PDF]

Front Physiol
Wang S, Zhen J, Xiao T.
europepmc   +1 more source

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

Advanced Science, EarlyView.
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi, Pierre Parutto, Yuyi Zhang, Tasuku Konno, Cecile Crapart, Raquel Pereira, John P. Franklin, Mosab Ali Awadelkareem, Daniel C Maddison, Michael J. Devine, Edgar R. Gomes, Joseph Chambers, Elena Koslover, Edward Avezov   +13 more
wiley   +1 more source

Kinesin‐Induced Buckling Reveals the Limits of Microtubule Self‐Repair

Advanced Science, EarlyView.
This study shows that kinesin‐driven buckling induces extensive microtubule lattice damage that often exceeds intrinsic self‐repair and leads to filament failure. While curvature, motor motility, and force individually cause limited damage, their combination overwhelms repair.
Shweta Nandakumar, Jonas Bosche, Mirko Wieczorek, Constantin Matteo Albrecht, Belinda König, Mona Grünewald, Ludger Santen, Stefan Diez, Reza Shaebani, Laura Schaedel   +9 more
wiley   +1 more source

Comparative Study of Hops Moisture Content and the Relative Humidity of the Drying Environment in a Hop Belt Dryer. [PDF]

Sensors (Basel)
Heřmánek P, Rybka A, Honzík I, Hlavsa T, Marčan J.   +4 more
europepmc   +1 more source