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Scaffold hopping

Drug Discovery Today: Technologies, 2004
The aim of scaffold hopping is to discover structurally novel compounds starting from known active compounds by modifying the central core structure of the molecule. Scaffold hopping is a central task of modern medicinal chemistry requiring a multitude of techniques, which are discussed in this article.
Hans-Joachim, Böhm   +2 more
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Hop by hop multicast routing protocol

Proceedings of the 2001 conference on Applications, technologies, architectures, and protocols for computer communications, 2001
IP Multicast is facing a slow take-off although it is a hotly debated topic since more than a decade. Many reasons are responsible for this status. Hence, the Internet is likely to be organized with both unicast and multicast enabled networks. Thus, it is of utmost importance to design protocols that allow the progressive deployment of the multicast ...
Maciel Kosmalski Costa, Luís Henrique   +2 more
openaire   +1 more source

Mechanisms of Hop Inhibition: Hop Ionophores

Journal of Agricultural and Food Chemistry, 2009
In this work, the mechanism of hop inhibition toward (beer spoiling) bacteria is revised. The mode of action of iso-alpha-acids was investigated via bilayer lipid membrane (BLM) measurements and growth challenges of hop-sensitive and -resistant Lactobacillus brevis strains in the presence of uncouplers of class I and II or a H(+)/Mn(2+) exchanger.
Jürgen, Behr, Rudi F, Vogel
openaire   +2 more sources

High-field hopping and ‘hopping domains’

Philosophical Magazine B, 2001
Abstract The non-ohmic hopping conductivities of a large number of samples of lightly doped by various impurities (P. As, Sb, B and Ga) and weakly compensated n-and p-type Si were investigated. The current-voltage (I-V) characteristics appeared to be different in two temperature regions typical for the studies of Ohmic hopping conductivity: the low ...
D. I. Aladashvili, Z. A. Adamia
openaire   +1 more source

Hop-by-hop or longer hops: The energy perspective

2008 International Conference on Innovations in Information Technology, 2008
We investigate, model and compare the expected energy consumption of routing over many short hops to the expected energy consumption of routing over longer hops. In addition to the common energy cost metrics of transmission and reception, our energy cost model also includes idle, noise, multi-path fading and retransmission energy costs.
Farinaz Koushanfar, Negar Kiyavash
openaire   +1 more source

Hopping Hoops Don't Hop

The American Mathematical Monthly, 1999
The dynamical behavior of a massless hoop with an attached point mass under the influence of gravity is an old chestnut, with some surprising features, including the question of whether or not it can "hop". It appears in Littlewood's Miscellany [1] and most recently in this MONTHLY [2].
openaire   +1 more source

Network coding for hop-by-hop communication enhancement in multi-hop networks

Computer Networks, 2016
In our recent study, we introduced the PlayNCool protocol that increases thethroughput of the wireless networks by enabling a helper node to strengthenthe communication link between two neighboring nodes and using randomlinear network coding. This paper focuses on design and implementationadvantages of the PlayNCool protocol in a real environment of ...
Pahlevani, Peyman   +4 more
openaire   +2 more sources

Short-Hops vs. Long-Hops

2014
Sensor networks are composed of miniaturized wireless sensor nodes with limited capacity and energy source. Generally, these sensor networks are used, in many applications, to monitor inaccessible environments (battlefields, volcano monitoring, animal tracking…), hence the impossibility to replace or to recharge the batteries.
Mekkaoui Kheireddine, Rahmoun Abdellatif
openaire   +1 more source

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