Results 21 to 30 of about 138,714 (357)

Cumulus cells gene expression profiling in terms of oocyte maturity in controlled ovarian hyperstimulation using GnRH agonist or GnRH antagonist. [PDF]

PLoS ONE, 2012
In in vitro fertilization (IVF) cycles controlled ovarian hyperstimulation (COH) is established by gonadotropins in combination with gonadotropin-releasing hormone (GnRH) agonists or antagonists, to prevent premature luteinizing hormone (LH) surge.
Rok Devjak, Klementina Fon Tacer, Peter Juvan, Irma Virant Klun, Damjana Rozman, Eda Vrtačnik Bokal   +5 more
doaj   +1 more source

The relationships between vitamin K and cognition: a review of current evidence [PDF]

, 2019
Vitamin K is a fat-soluble nutrient discovered in 1935 and its role in blood coagulation has been thoroughly explored. In recent years, studies conducted in vitro and on animals highlighted vitamin K involvement in brain cells development and survival ...
Alisi, Ludovico, Cafolla, Arturo, Cao, Roberta, Caramia, Francesca, Cartocci, Gaia, De Angelis, Cristina, Fiorelli, Marco, Librando, Aloisa   +7 more
core   +2 more sources

Small Molecule Follicle-Stimulating Hormone Receptor Agonists and Antagonists

Frontiers in Endocrinology, 2019
The follicle-stimulating hormone receptor (FSHR) has been targeted therapeutically for decades, due to its pivotal role in reproduction. To date, only purified and recombinant/biosimilar FSH have been used to target FSHR in assisted reproduction, with ...
Ross C. Anderson, Claire L. Newton, Robert P. Millar, Robert P. Millar   +3 more
doaj   +1 more source

Progress in Clinical Research on Gonadotropin-Releasing Hormone Receptor Antagonists for the Treatment of Prostate Cancer

Drug Design, Development and Therapy, 2021
Yi-Fu Liu, Sheng-Qiang Fu, Yu-Chang Yan, Bin-Bin Gong, Wen-Jie Xie, Xiao-Rong Yang, Ting Sun, Ming Ma Department of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, 330000, Jiangxi Province, People’s Republic of ...
Liu YF, Fu SQ, Yan YC, Gong BB, Xie WJ, Yang XR, Sun T, Ma M   +7 more
doaj  

Growth Hormone-Releasing Hormone in Lung Physiology and Pulmonary Disease

Cells, 2020
Growth hormone-releasing hormone (GHRH) is secreted primarily from the hypothalamus, but other tissues, including the lungs, produce it locally.
Chongxu Zhang, Tengjiao Cui, Renzhi Cai, Medhi Wangpaichitr, Mehdi Mirsaeidi, Andrew V. Schally, Robert M. Jackson   +6 more
doaj   +1 more source

Expression of Growth Hormone-Releasing Hormone and Its Receptor Splice Variants in Primary Human Endometrial Carcinomas: Novel Therapeutic Approaches

Molecules, 2022
Antagonists of growth hormone-releasing hormone (GHRH) inhibit the growth of various tumors, including endometrial carcinomas (EC). However, tumoral receptors that mediate the antiproliferative effects of GHRH antagonists in human ECs have not been fully
Zsuzsanna Szabo, Eva Juhasz, Andrew V. Schally, Balazs Dezso, Sandor Huga, Zoltan Hernadi, Gabor Halmos, Csongor Kiss   +7 more
doaj   +1 more source

Pheochromocytoma – clinical manifestations, diagnosis and current perioperative management [PDF]

, 2019
Pheochromocytoma is a neuroendocrine tumor characterized by the excessive production of catecholamines (epinephrine, norepinephrine, and dopamine). The diagnosis is suspected due to hypertensive paroxysms, associated with vegetative phenomena, due to the
Bratu, Ovidiu G, Diaconu, Camelia C, Gaman, Mihnea A, Manea, Maria, Marcu, Dragos R, Pantea Stoian, Anca, Stanescu, Ana M   +6 more
core   +2 more sources

Effectiveness of GnRH Antagonists and Agonists in Patients with Hormone-Sensitive Prostate Cancer: A Retrospective Study

Applied Bionics and Biomechanics, 2022
Objective. To assess the effectiveness of gonadotropin-releasing hormone (GnRH) antagonists and agonists in the treatment of patients with hormone-sensitive prostate cancer (HSPC), thus providing valid data support for their clinical treatment.
Zhenghao Liu, Chunguang Yang, Xing Zeng, Chunjin Ke, Jihua Tian, Zhihua Wang, Zhiquan Hu   +6 more
doaj   +1 more source

Unfolded Protein Response: A Regulator of the Endothelial Barrier

Endocrine and Metabolic Science, 2021
Recent evidence suggest that the endothelial barrier function is enhanced by the mild activation of the unfolded protein response (UPR), which aims to suppress abnormal increases of endoplasmic reticulum stress.
Nektarios Barabutis
doaj   +1 more source

ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer. [PDF]

, 2016
The androgen receptor (AR) is overexpressed and hyperactivated in human castration-resistant prostate cancer (CRPC). However, the determinants of AR overexpression in CRPC are poorly defined.
Borowsky, Alexander D, Cai, Demin, Chen, Hong-Wu, Duan, Zhijian, Evans, Christopher P, Evans, Ronald M, Gao, Allen C, Kung, Hsing-Jien, Lam, Kit S, Louie, Maggie C, Wang, Junjian, Xiang, Qiuping, Xu, Jianzhen, Xu, Yong, Xue, Xiaoqian, Yang, Joy C, Zhang, Yan, Zou, June X   +17 more
core   +2 more sources