Results 21 to 30 of about 136,105 (353)

Effect of chronic restraint stress on human colorectal carcinoma growth in mice. [PDF]

PLoS ONE, 2013
Stress alters immunological and neuroendocrinological functions. An increasing number of studies indicate that chronic stress can accelerate tumor growth, but its role in colorectal carcinoma (CRC) progression is not well understood.
Qiang Lin, Feifei Wang, Rong Yang, Xinmin Zheng, Huibao Gao, Ping Zhang   +5 more
doaj   +1 more source

The relationships between vitamin K and cognition: a review of current evidence [PDF]

, 2019
Vitamin K is a fat-soluble nutrient discovered in 1935 and its role in blood coagulation has been thoroughly explored. In recent years, studies conducted in vitro and on animals highlighted vitamin K involvement in brain cells development and survival ...
Alisi, Ludovico, Cafolla, Arturo, Cao, Roberta, Caramia, Francesca, Cartocci, Gaia, De Angelis, Cristina, Fiorelli, Marco, Librando, Aloisa   +7 more
core   +2 more sources

New Topics in Vasopressin Receptors and Approach to Novel Drugs: Effects of Vasopressin Receptor on Regulations of Hormone Secretion and Metabolisms of Glucose, Fat, and Protein

Journal of Pharmacological Sciences, 2009
The neurohypophyseal peptide [Arg8]-vasopressin (AVP) is involved in diverse functions such as the regulation of body fluid homeostasis, metabolism, and hormone secretion.
Akito Tanoue
doaj   +1 more source

Influence of mirtazapine on salivary cortisol in depressed patients [PDF]

, 2003
Unlike other antidepressants, mirtazapine does not inhibit the reuptake of norepinephrine or serotonin but acts as an antagonist at presynaptic alpha(2)-receptors, at postsynaptic 5-HT2 and 5-HT3 receptors, and at histaminergic H1 receptors. Furthermore,
Baghai, Thomas C., Hennig, J., Laakmann, G., Schule, C.   +3 more
core   +1 more source

Cumulus cells gene expression profiling in terms of oocyte maturity in controlled ovarian hyperstimulation using GnRH agonist or GnRH antagonist. [PDF]

PLoS ONE, 2012
In in vitro fertilization (IVF) cycles controlled ovarian hyperstimulation (COH) is established by gonadotropins in combination with gonadotropin-releasing hormone (GnRH) agonists or antagonists, to prevent premature luteinizing hormone (LH) surge.
Rok Devjak, Klementina Fon Tacer, Peter Juvan, Irma Virant Klun, Damjana Rozman, Eda Vrtačnik Bokal   +5 more
doaj   +1 more source

KMT2C mediates the estrogen dependence of breast cancer through regulation of ERα enhancer function [PDF]

, 2018
Estrogen receptor alpha (ER alpha) is a ligand-activated nuclear receptor that directs proliferation and differentiation in selected cancer cell types including mammary-derived carcinomas.
Abdel-Wahab, Omar, Berger, Michael, Chandarlapaty, Sarat, Chung, Young Rock, Dorso, Madeline, Gala, Kinisha, Hendrickson, Ronald, Hsieh, James J, Li, Qing, Pastore, Alessandro, Razavi, Pedram, Sanchez-Vega, Francisco, Schultz, Nikolaus, Sinha, Amit   +13 more
core   +2 more sources

Small Molecule Follicle-Stimulating Hormone Receptor Agonists and Antagonists

Frontiers in Endocrinology, 2019
The follicle-stimulating hormone receptor (FSHR) has been targeted therapeutically for decades, due to its pivotal role in reproduction. To date, only purified and recombinant/biosimilar FSH have been used to target FSHR in assisted reproduction, with ...
Ross C. Anderson, Claire L. Newton, Robert P. Millar, Robert P. Millar   +3 more
doaj   +1 more source

Progress in Clinical Research on Gonadotropin-Releasing Hormone Receptor Antagonists for the Treatment of Prostate Cancer

Drug Design, Development and Therapy, 2021
Yi-Fu Liu, Sheng-Qiang Fu, Yu-Chang Yan, Bin-Bin Gong, Wen-Jie Xie, Xiao-Rong Yang, Ting Sun, Ming Ma Department of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, 330000, Jiangxi Province, People’s Republic of ...
Liu YF, Fu SQ, Yan YC, Gong BB, Xie WJ, Yang XR, Sun T, Ma M   +7 more
doaj  

Growth Hormone-Releasing Hormone in Lung Physiology and Pulmonary Disease

Cells, 2020
Growth hormone-releasing hormone (GHRH) is secreted primarily from the hypothalamus, but other tissues, including the lungs, produce it locally.
Chongxu Zhang, Tengjiao Cui, Renzhi Cai, Medhi Wangpaichitr, Mehdi Mirsaeidi, Andrew V. Schally, Robert M. Jackson   +6 more
doaj   +1 more source

Expression of Growth Hormone-Releasing Hormone and Its Receptor Splice Variants in Primary Human Endometrial Carcinomas: Novel Therapeutic Approaches

Molecules, 2022
Antagonists of growth hormone-releasing hormone (GHRH) inhibit the growth of various tumors, including endometrial carcinomas (EC). However, tumoral receptors that mediate the antiproliferative effects of GHRH antagonists in human ECs have not been fully
Zsuzsanna Szabo, Eva Juhasz, Andrew V. Schally, Balazs Dezso, Sandor Huga, Zoltan Hernadi, Gabor Halmos, Csongor Kiss   +7 more
doaj   +1 more source