Results 81 to 90 of about 791,574 (359)
Prevention and treatment of venous thromboembolism during HRT: current perspectives
International Journal of General Medicine, 2014 Hannelore Rott Coagulation Center Rhine-Ruhr, Duisburg, Germany Abstract: Many large trials in the past 15 years have proven an increased risk of vascular complications in women using oral, mostly non-bioidentical, hormone therapy.
Rott H
doaj
Oral contraceptives combined with interferon β in multiple sclerosis [PDF]
, 2015 Objective: To test the effect of oral contraceptives (OCs) in combination with interferon b (IFN-b) on disease activity in patients with relapsing-remitting multiple sclerosis (RRMS).
Barletta, Valeria T. +10 more
core +3 more sources
Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node
FEBS Open Bio, EarlyView.The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner +6 more
wiley +1 more source
Hormonal therapy: introduction
The Breast, 2003 For more than a quarter of a century, tamoxifen has dominated the endocrine treatment of breast cancer. Recently, this has started to change. Anastrozole, letrozole and exemestane are so-called third-generation aromatase inhibitors that have much greater specificity and potency than their first-generation and second-generation predecessors for the ...
openaire +2 more sources
FEBS Open Bio, EarlyView.Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley +1 more source
Hormone therapy for diffuse mastopathy
Опухоли женской репродуктивной системы, 2014 The paper considers the issues of hormone therapy for diffuse fibrocystic mastopathy concurrent with different hormonal homeostatic disorders and gynecological diseases.
I. V. Vysotskaya +2 more
doaj +1 more source
Current medical treatment of estrogen receptor-positive breast cancer [PDF]
, 2015 Approximately 80% of breast cancers (BC) are estrogen receptor (ER)-positive and thus endocrine therapy (ET) should be considered complementary to surgery in the majority of patients.
Basso, S. M. M. +2 more
core +1 more source
SmallTalk: a novel small‐sized fusion tag for peptide expression and purification
FEBS Open Bio, EarlyView.The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq +3 more
wiley +1 more source
Menopausal hormone therapy: oncological risks
Лечащий Врач, 2021 The article presents generalized data on cancer risks during menopausal hormone therapy (MHT). It is shown that, in proper MHT prescription, it is possible to achieve targeted treatment outcomes without increasing cancer risk.
I. V. Madyanov, T. S. Madyanova
doaj
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
FEBS Open Bio, EarlyView.Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source