Results 21 to 30 of about 818,880 (342)

Gallic acid against hepatocellular carcinoma: An integrated scheme of the potential mechanisms of action from study

Tumor Biology, 2017
The global burden of hepatocellular carcinoma is increasing; actually, it is estimated as 750,000 new cases annually. This study was initiated to emphasize the possibility that gallic acid could alleviate hepatocarcinogenesis in vivo .
Hadeer A Aglan, Hanaa H Ahmed, Sayed A El-Toumy, Nadia S Mahmoud   +3 more
doaj   +1 more source

Unbinding of Retinoic Acid from its Receptor Studied by Steered Molecular Dynamics [PDF]

Biophysical Journal 76, 188 (1999), 1999
Retinoic acid receptor (RAR) is a ligand-dependent transcription factor that regulates the expression of genes involved in cell growth, differentiation, and development. Binding of the retinoic acid hormone to RAR is accompanied by conformational changes in the protein which induce transactivation or transrepression of the target genes.
arxiv   +1 more source

SlMYB75, an MYB-type transcription factor, promotes anthocyanin accumulation and enhances volatile aroma production in tomato fruits

Horticulture Research, 2019
Genetics: one small tweak, one giant leap for tomatoes A single gene has been identified in tomatoes that regulates multiple aspects of fruit quality, including levels of health-promoting anthocyanins, opening the door to engineering more nutritious and ...
Wei Jian, Haohao Cao, Shu Yuan, Yudong Liu, Juanfang Lu, Wang Lu, Ning Li, Jianhui Wang, Jian Zou, Ning Tang, Chan Xu, Yulin Cheng, Yanqiang Gao, Wanpeng Xi, Mondher Bouzayen, Zhengguo Li   +15 more
doaj   +1 more source

Senescence-associated 13-HODE production promotes age-related liver steatosis by directly inhibiting catalase activity

Nature Communications, 2023
Aging is a major risk factor for metabolic disorders. Polyunsaturated fatty acid-derived bioactive lipids play critical roles as signaling molecules in metabolic processes. Nonetheless, their effects on age-related liver steatosis remain unknown. Here we
Jinjie Duan, Wenhui Dong, Guangyan Wang, Wenjing Xiu, Guangyin Pu, Jingwen Xu, Chenji Ye, Xu Zhang, Yi Zhu, Chunjiong Wang   +9 more
doaj   +1 more source

Ras Guanine Nucleotide-Releasing Protein-4 Inhibits Erythropoietin Production in Diabetic Mice with Kidney Disease by Degrading HIF2A [PDF]

Diabetes & Metabolism Journal
Background In acute and chronic renal inflammatory diseases, the activation of inflammatory cells is involved in the defect of erythropoietin (EPO) production.
Junmei Wang, Shuai Huang, Li Zhang, Yixian He, Xian Shao, A-Shan-Jiang A-Ni-Wan, Yan Kong, Xuying Meng, Pei Yu, Saijun Zhou   +9 more
doaj   +1 more source

Citrus Postharvest Green Mold: Recent Advances in Fungal Pathogenicity and Fruit Resistance

Microorganisms, 2020
As the major postharvest disease of citrus fruit, postharvest green mold is caused by the necrotrophic fungus Penicillium digitatum (Pd), which leads to huge economic losses worldwide.
Yulin Cheng, Yunlong Lin, Haohao Cao, Zhengguo Li   +3 more
doaj   +1 more source

Auxin response factor 6A regulates photosynthesis, sugar accumulation, and fruit development in tomato

Horticulture Research, 2019
Auxin response factors (ARFs) are involved in auxin-mediated transcriptional regulation in plants. In this study, we performed functional characterization of SlARF6A in tomato.
Yujin Yuan, Xin Xu, Zehao Gong, Yuwei Tang, Mengbo Wu, Fang Yan, Xiaolan Zhang, Qian Zhang, Fengqing Yang, Xiaowei Hu, Qichen Yang, Yingqing Luo, Lihua Mei, Wenfa Zhang, Cai-Zhong Jiang, Wangjin Lu, Zhengguo Li, Wei Deng   +17 more
doaj   +1 more source

Growth Hormone-Releasing Hormone in Diabetes [PDF]

Frontiers in Endocrinology, 2016
Growth hormone-releasing hormone (GHRH) is produced by the hypothalamus and stimulates growth hormone synthesis and release in the anterior pituitary gland. In addition, GHRH is an important regulator of cellular functions in many cells and organs.
Louis H. Philipson, Leonid E. Fridlyand, Andrew V. Schally, Andrew V. Schally, Natalia A. Tamarina   +4 more
openaire   +4 more sources

Label-free assaying of testosterone and growth hormones in blood using surface-enhanced raman spectroscopy [PDF]

arXiv, 2023
This work reports the potential use of surface enhanced Raman spectroscopy (SERS) in rapid, label-free assaying of testosterone (TE) and growth hormone (GH) in whole blood. Biomarker SERS spectral bands from the two hormones (TE and GH) in intentionally spiked water for injection and in male Sprague-Dawley (SD) rat blood are reported.
arxiv  

Hormones, damned hormones, and statistics [PDF]

BJOG: An International Journal of Obstetrics & Gynaecology, 2017
Deputy Editor‐in‐Chief, Dr Michael Marsh, discusses his top articles from this issue in an audio podcast available at: https://soundcloud.com/bjog/september-editors-choice-2017.
openaire   +3 more sources