Results 111 to 120 of about 81,715,713 (310)

University Hospitals Staff Meeting Bulletin, May 10, 1934

open access: yes, 1934
University of Minnesota. University of Minnesota Hospitals. (1934). University Hospitals Staff Meeting Bulletin, May 10, 1934.
University of Minnesota. University of Minnesota Hospitals
core  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

University Hospitals Staff Meeting Bulletin, October 25, 1934

open access: yes, 1934
University of Minnesota. University of Minnesota Hospitals. (1934). University Hospitals Staff Meeting Bulletin, October 25, 1934.
University of Minnesota. University of Minnesota Hospitals
core  

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

University Hospitals Staff Meeting Bulletin, April 23, 1936

open access: yes, 1936
University of Minnesota. University of Minnesota Hospitals. (1936). University Hospitals Staff Meeting Bulletin, April 23, 1936.
University of Minnesota. University of Minnesota Hospitals
core  

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

University Hospitals General Staff Meeting, February 4, 1932

open access: yes, 1932
University of Minnesota. University of Minnesota Hospitals. (1932). University Hospitals General Staff Meeting, February 4, 1932.
University of Minnesota. University of Minnesota Hospitals
core  

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

University Hospitals General Staff Meeting, February 5, 1931

open access: yes, 1931
University of Minnesota. University of Minnesota Hospitals. (1931). University Hospitals General Staff Meeting, February 5, 1931.
University of Minnesota. University of Minnesota Hospitals
core  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

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