Results 91 to 100 of about 78,496,881 (308)

Factors influencing medical students' decisions to remain at their alma mater for postgraduate clinical training: A cross-sectional study in Japan.

open access: yesPLoS ONE
BackgroundDespite structured postgraduate clinical training programs in Japan, a considerable number of medical graduates have recently preferred community hospitals to university hospitals for postgraduate clinical training.
Keiko Hamatsu   +5 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Hospitals universitários: avaliação comparativa de eficiência técnica

open access: yesEconomia Aplicada, 2000
This paper presents an exercise on comparative efficiency evaluation ofBrazilian federal university hospitals HUs (43 organizations). The methodology used is Data Envelopment Analysis - DEA, along with statistical non-parametric procedures and specific ...
Alexandre Marinho   +1 more
doaj  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Non-specialized inpatient care provided by university hospitals in Japan

open access: yesRisk Management and Healthcare Policy, 2008
Shin-ichi ToyabeCrisis Management Office, Niigata University Hospital, Niigata City, JapanAbstract: In Japan, all citizens are covered by the national insurance system in which universal free access to healthcare services is promised to everybody.
Shin-ichi Toyabe
doaj  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

University Hospitals Staff Conference, October 2, 1930

open access: yes, 1930
University of Minnesota. University of Minnesota Hospitals. (1930). University Hospitals Staff Conference, October 2, 1930.
University of Minnesota. University of Minnesota Hospitals
core  

Potential drug-drug interactions in a Brazilian teaching hospital: age-related differences?

open access: yesRevista de Ciências Farmacêuticas Básica e Aplicada, 2015
This study proposes to measure frequency and to characterize the profile of potential drug interactions (pDDI) in a general medicine ward of a teaching hospital.
Daniela Oliveira de Melo   +2 more
doaj  

A Response to the Study “Lifestyle Counseling for Medication Adherence in Glaucoma” [Letter]

open access: yesClinical Ophthalmology, 2021
Lois Crabtree Epsom and St Helier University Hospitals, Epsom, UKCorrespondence: Lois CrabtreeEpsom and St Helier University Hospitals, Epsom, UKEmail loiscrabtree@hotmail.co.uk; lois.crabtree1@nhs.net View the original paper by Dr Kim and ...
Crabtree L
doaj  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

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