Results 101 to 110 of about 81,715,713 (310)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Potential drug-drug interactions in a Brazilian teaching hospital: age-related differences?

Revista de Ciências Farmacêuticas Básica e Aplicada, 2015
This study proposes to measure frequency and to characterize the profile of potential drug interactions (pDDI) in a general medicine ward of a teaching hospital.
Daniela Oliveira de Melo, Eliane Ribeiro, Sílvia Storpirtis   +2 more
doaj  

A University Hospital [PDF]

Proceedings of the Royal Society of Medicine, 1970
openaire   +2 more sources

University Hospitals Annual Report, 1955-1956

, 1956
University of Minnesota. University Hospitals and Clinics. (1956). University Hospitals Annual Report, 1955-1956.
University of Minnesota. University Hospitals and Clinics
core  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

University Hospitals General Staff Meeting, May 21, 1931

, 1931
University of Minnesota. University of Minnesota Hospitals. (1931). University Hospitals General Staff Meeting, May 21, 1931.
University of Minnesota. University of Minnesota Hospitals
core  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

University Hospitals General Staff Meeting, February 16, 1933

, 1933
University of Minnesota. University of Minnesota Hospitals. (1933). University Hospitals General Staff Meeting, February 16, 1933.
University of Minnesota. University of Minnesota Hospitals
core  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Environmental disclosure of healthcare waste in public university hospitals in Brazil: diagnosis and proposal of a disclosure model aimed at transparency and sustainability

Revista Ambiente Contábil
Purpose: Propose an environmental disclosure model for healthcare waste aimed at public university hospitals in Brazil. Methodology: The research, of a descriptive nature, employed content analysis of reports published by university hospitals and ...
Fabrícia Silva da Rosa, Juliana dos Anjos   +1 more
doaj   +1 more source