Results 271 to 280 of about 11,515,911 (324)

Reconstructing host-pathogen interactions: analysis of the intercellular network of macrophages and other immune cells within an aspergillosis-on-chip model. [PDF]

Microlife
Kaur S, Renner AK, Porschitz P, Schmidt F, Grau S, Afolayan H, Schmidt S, Lehrnbecher-Lanzeni T, Haas H, Brakhage AA, Figge MT, von Lilienfeld-Toal M, Cseresnyés Z, Hartung S, Jahreis S.   +14 more
europepmc   +1 more source

The MoSR‐MoDde1 Regulatory Axis: A Novel Determinant of DMI Sensitivity and a Target for Sustainable Rice Blast Control

Advanced Science, EarlyView.
The transcription factor MoSR governs DMI fungicide sensitivity in Magnaporthe oryzae through dual regulation of ergosterol biosynthesis and the detoxification enzyme MoDde1. Targeting MoDde1 via a small‐molecule inhibitor or host‐induced gene silencing enhances DMI efficacy against rice blast, offering a sustainable disease management strategy ...
Fan‐Zhu Meng, Wen‐Kai Wei, Meng‐Yao Wu, Min‐Zheng Cai, Yu‐Fu Wang, Li Zhao, Shuai Meng, Liang‐Fen Yin, Guido Schnabel, Wei‐Xiao Yin, Chao‐Xi Luo   +10 more
wiley   +1 more source

Molecular investigation of tick-borne and zoonotic pathogen dissemination and host-pathogen interactions in canines. [PDF]

Sci Rep
Fatima A, Umer M, Rasool M, Yasmeen T, Muqaddas H, Nisa TU, Danish MF, Khalil MA, Alyami EM, Alghamdi OA, Elossaily GM, Tesemma M, Shahzadi W, Ullah S, Iqbal F.   +14 more
europepmc   +1 more source

Neuron‐Derived Vesicular circMagi1 Restrains Vascular Repair After Ischemic Stroke by Promoting TRIM65‐Mediated ANXA2 Degradation

Advanced Science, EarlyView.
After ischemic stroke, injured neurons transfer circMagi1 to endothelial cells through extracellular vesicles. Within endothelial cells, circMagi1 binds ANXA2 and enhances its engagement with TRIM65, promoting ANXA2 ubiquitination and proteasomal degradation to constrain angiogenic repair.
Youkun Bi, Qun Liu, Baohua Zou, Wenyuan Wang, Xinlong Qiao, Lin Gao, Chaoxu Miao, Ningning Huang, Shuqing Tang, Rui Guo, Changqing Zeng, Ce Jia, Yuanchao Xue, Xuejun Guo, Jianjun Chen, Huiwen Wang, Guangju Ji   +16 more
wiley   +1 more source

Correction: A simple <i>ex vivo</i> bladder infection model permits study of host-pathogen interactions in urinary tract infection. [PDF]

FEMS Microbes
europepmc   +1 more source

Host-Pathogen Interactions in Cystic Fibrosis Lung Disease: Adaptation, Persistence, and Clinical Implications of <i>Pseudomonas aeruginosa</i>. [PDF]

Pathogens
Capraz Yavuz B.
europepmc   +1 more source

Acid‐Responsive Nanobot‐Integrated Core‐Shell Microneedles Reprogram the Degenerative Annulus Fibrosus Microenvironment Through Epigenetic Suppression of Ferroptosis

Advanced Science, EarlyView.
An acid‐responsive core‐shell microneedle system normalizes the degenerative annulus fibrosus microenvironment by consuming pathological H+, generating O2, and providing NIR‐amplified redox buffering. Mechanistically, it epigenetically suppresses ferroptosis via DNMT3A‐dependent methylation of the ATF3 promoter, relieving ATF3‐mediated repression of ...
Lu Tan, Yan Zheng, Yue Lan, Zhuo Cheng, Siya Wang, Changqing Li, Yanqiu Wang, Minghan Liu   +7 more
wiley   +1 more source

mimicDetector: a pipeline for protein motif mimicry detection in host-pathogen interactions. [PDF]

Bioinformatics
Rich KD, Wasmuth JD.
europepmc   +1 more source

A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior

Advanced Science, EarlyView.
Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li, Ying‐Dan Zhang, Wei Wang, Xin‐Yi Wu, Di Li, Xin Gong, Fei Tian, Meng‐Yu Dai, Jian Gao, Zi‐Feng Zheng, Zi‐Yang Bi, Dong‐Dong Shi, Zhen Wang   +12 more
wiley   +1 more source

Profiling of human and microbial cell-free DNA reflects early host-pathogen interactions in sepsis. [PDF]

Front Immunol
Hoeter K, Neuberger EWI, Marriott L, De Falco A, Wiemann S, Schäfer MKE, Simon P, Kersaudy-Kerhoas M, Bodenstein M.   +8 more
europepmc   +1 more source