Results 41 to 50 of about 11,515,911 (324)

Emerging roles of the complement system in host-pathogen interactions

Trends in Microbiology, 2021
The complement system has historically been entertained as a fluid-phase, hepatically-derived system, which protects the intravascular space from encapsulated bacteria. However, there has been an increasing appreciation for its role in protection against
S. Sahu, Devesha H. Kulkarni, Aysegul Ozanturk, Li-Na Ma, H. Kulkarni   +4 more
semanticscholar   +1 more source

Pathogen-host reorganization during Chlamydia invasion revealed by cryo-electron tomography [PDF]

, 2014
Invasion of host cells is a key early event during bacterial infection, but the underlying pathogen-host interactions are yet to be fully visualised in three-dimensional detail.
Hayward, Richard, Nans, Andrea, Saibil, HR, Hayward, RD, Saibil, Helen R., Nans, A   +5 more
core   +1 more source

Controlling Epithelial Polarity: A Human Enteroid Model for Host-Pathogen Interactions

Cell Reports, 2019
Summary Human enteroids—epithelial spheroids derived from primary gastrointestinal tissue—are a promising model to study pathogen-epithelial interactions.
Julia Y. Co, Mar Margalef-Català, Xing-Nan Li, Amanda T. Mah, Calvin J. Kuo, D. Monack, M. Amieva   +6 more
semanticscholar   +1 more source

The Ubiquitination System within Bacterial Host–Pathogen Interactions

Microorganisms, 2021
Ubiquitination of proteins, like phosphorylation and acetylation, is an important regulatory aspect influencing numerous and various cell processes, such as immune response signaling and autophagy.
Vera Vozandychova, Pavla Stojkova, K. Hercík, P. Rehulka, J. Stulík   +4 more
semanticscholar   +1 more source

PHI-base: the pathogen-host interactions database. [PDF]

, 2019
The pathogen-host interactions database (PHI-base) is available at www.phi-base.org. PHI-base contains expertly curated molecular and biological information on genes proven to affect the outcome of pathogen-host interactions reported in peer reviewed ...
Wood, V., Yates, A. D., Hassani-Pak, K., Rutherford, K., Pedro, H., Seager, J., De Silva, N., Venkatesh, S. Y, Urban, M., Martinez, M. C., Cuzick, A., Hammond-Kosack, K. E., Urban, Martin, Seager, James, Hassani-Pak, Keywan, Hammond-Kosack, Kim, Cuzick, Alayne   +16 more
core   +3 more sources

Bacillus cereus: Epidemiology, Virulence Factors, and Host-Pathogen Interactions.

Trends in Microbiology, 2020
The toxin-producing bacterium Bacillus cereus is an important and neglected human pathogen and a common cause of food poisoning. Several toxins have been implicated in disease, including the pore-forming toxins hemolysin BL (HBL) and nonhemolytic ...
Daniel Enosi Tuipulotu, A. Mathur, Chinh C. Ngo, Ming-Man Si   +3 more
semanticscholar   +1 more source

The molecular basis of host specialization in bean pathovars of Pseudomonas syringae [PDF]

, 2012
Biotrophic phytopathogens are typically limited to their adapted host range. In recent decades, investigations have teased apart the general molecular basis of intraspecific variation for innate immunity of plants, typically involving receptor ...
Baltrus, David A., Biswas, Surojit, Vicente, Joana G., Nishimura, Marc T., Holub, E. B., Mukhtar, M. Shahid, Dougherty, Kevin M., Dangl, J. L. (Jeffery L.)   +7 more
core   +1 more source

The Development of Ovine Gastric and Intestinal Organoids for Studying Ruminant Host-Pathogen Interactions

bioRxiv, 2021
Gastrointestinal (GI) infections in sheep have significant implications for animal health, welfare and productivity, as well as being a source of zoonotic pathogens.
David Smith, D. Price, A. Burrells, M. Faber, Katie A. Hildersley, C. Chintoan-Uta, A. Chapuis, M. Stevens, K. Stevenson, S. Burgess, E. Innes, A. Nisbet, T. McNeilly   +12 more
semanticscholar   +1 more source

PHI-base: a new interface and further additions for the multi-species pathogen–host interactions database [PDF]

, 2016
The pathogen–host interactions database (PHI-base) is available at www.phi-base.org. PHI-base contains expertly curated molecular and biological information on genes proven to affect the outcome of pathogen–host interactions reported in peer reviewed ...
Khamari, L., Pant, R., Irvine, A. G., Rutherford, K., Pedro, H., Sadanadan, V., Mohanty, Sagar, Billal, S., Urban, M., Cuzick, A., Hammond-Kosack, K. E., Urban, Martin, Hammond-Kosack, Kim, Cuzick, Alayne   +13 more
core   +1 more source

Mycobacterium tuberculosis Modulates miR-106b-5p to Control Cathepsin S Expression Resulting in Higher Pathogen Survival and Poor T-Cell Activation

Frontiers in Immunology, 2017
The success of tuberculosis (TB) bacillus, Mycobacterium tuberculosis (Mtb), relies on the ability to survive in host cells and escape to immune surveillance and activation.
David Pires, Elliott M. Bernard, João Palma Pombo, Nuno Carmo, Catarina Fialho, Maximiliano Gabriel Gutierrez, Paulo Bettencourt, Elsa Anes   +7 more
doaj   +1 more source