Results 141 to 150 of about 2,543,243 (267)

A Citrulline‐Functionalized Patch Coordinates Macrophage NRF2 Signaling and Arginine Metabolism for Tendon‐to‐Bone Repair

Advanced Science, EarlyView.
A locally implanted patch combines citrulline‐functionalized carbon dots, a thioketal‐containing membrane coating from tendon‐derived stem cells, and aligned core–shell fibers. In macrophages, the patch reduces inflammatory markers and enhances antioxidant signaling through nuclear factor erythroid 2‐related factor 2 (NRF2); in rats and rabbits, it ...
Yuhao Yu, Wencai Liu, Xinyue Yang, Hanzhe Zhang, Hui Xu, Xin Wang, Weimin Lin, Xiping Jiang, Chenrui Yuan, Yifei Wang, Weilin Yu, Yamin Li, Wei Song, Yaohua He   +13 more
wiley   +1 more source

Discovery of Novel Thanatin-like Antimicrobial Peptides from Bean Bug Riptortus pedestris

Pharmaceutics
Background: Endogenous antimicrobial peptides (AMPs) are evolutionarily ancient molecular factors of innate immunity that play a key role in host defense.
Pavel V. Panteleev, Julia S. Teplovodskaya, Anastasia D. Utkina, Anastasia A. Smolina, Roman N. Kruglikov, Victoria N. Safronova, Ilia A. Bolosov, Olga V. Korobova, Alexander I. Borzilov, Tatiana V. Ovchinnikova   +9 more
doaj   +1 more source

Purification, Conformational Analysis and Cytotoxic Activities of Host-Defense Peptides from the Giant Gladiator Treefrog Boana boans (Hylidae: Hylinae). [PDF]

Antibiotics (Basel), 2023
Conlon JM, Guilhaudis L, Attoub S, Coquet L, Leprince J, Jouenne T, Mechkarska M.   +6 more
europepmc   +1 more source

Multifunctional host defense peptides [PDF]

The FEBS Journal, 2009
Pierre Nicolas, Yvonne Rosenstein
openaire   +1 more source

Host defense peptides in fish: from the peculiar to the mainstream

, 2009
In this chapter, the authors explains genetic, structural and functional relatives of non-fish host defense peptides in fish, and they devote a portion of this discussion to each of these topics.
Patrzykat, A., Hancock, R. E. W.
core  

Host-defense peptides from skin secretions of the octoploid frogs Xenopus vestitus and Xenopus wittei (Pipidae): Insights into evolutionary relationships

, 2014
International audienceThe primary structures of host-defense peptides have proved useful in elucidating the evolution history of frogs. Peptidomic analysis was used to compare the diversity of host-defense peptides in norepinephrine-stimulated skin ...
Michalak, Katarzyna, Milena Mechkarska, Pawel Michalak, Hubert Vaudry, Jérôme Leprince, Coquet, Laurent, Conlon, J. Michael, J. Michael Conlon, Vaudry, Hubert, Jouenne, Thierry, Thierry Jouenne, Laurent Coquet, Mechkarska, Milena, Leprince, Jérôme, Michalak, Pawel, Katarzyna Michalak   +15 more
core   +1 more source

Functional Specialization of Respiratory and Olfactory Mucus Revealed by Proteomic Profiling

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Mucus overlies the nasal mucosa in the respiratory and olfactory regions, which perform distinct physiological functions. However, proteomic differences between respiratory mucosa (RM) and olfactory cleft (OC) mucus remain unclear.
Anna Kristina Hernandez, Karoline Lantzsch, Romain Topalian, Nadine Gunder, Philipp Hubel, Katharina Schindowski, Jens Pfannstiel, Thomas Hummel   +7 more
wiley   +1 more source

Translational Macrophage Mechano‐Immunotherapy for Next‐Generation Implantable Biomaterials

Advanced NanoBiomed Research, EarlyView.
This review explores how macrophage mechanosensing drives inflammation, fibrosis and foreign body responses to implanted biomaterials. It examines emerging pharmacological strategies to modulate mechanotransduction, alongside biomaterial platforms for localised drug delivery, clinical translation, regulatory considerations and standardised testing ...
Xueying Xu, Ian L. Chin, Richard P. Tan
wiley   +1 more source

Host defense peptides combined with MTA extract increase the repair in dental pulp cells: in vitro and ex vivo study. [PDF]

Sci Rep, 2023
Silva PAO, Martins DCM, de Castro Cantuária AP, de Andrade RV, Lacorte C, de Almeida JA, Aguiar LR, Corrêa JR, da Silva IGM, Franco OL, Rezende TMB.   +10 more
europepmc   +1 more source

Biomimetic Nanomedicine for Aging‐Impaired Bone Regeneration: From Microenvironmental Dysfunction to Precision Therapeutics

Advanced NanoBiomed Research, EarlyView.
Aging disrupts the cellular, immune, vascular, and neural processes required for bone regeneration. This review connects these pathological barriers with biomimetic nanomedicine design, highlighting strategies for cellular rejuvenation, immune modulation, vascular regeneration, and neuro–bone coupling.
Zeyu Wang, He Zhang, Simo Liu, Rui Wang, Yiran Wei, Kailu Zheng, Yanming Guo, Min Li, Dian Yuan, Yuxin Liu, Lifang Feng, Yongping Ma, Yan Liu   +12 more
wiley   +1 more source