Cathelicidins: Immunomodulatory Antimicrobials [PDF]
Vaccines, 2018 Cathelicidins are host defense peptides with antimicrobial and immunomodulatory functions. These effector molecules of the innate immune system of many vertebrates are diverse in their amino acid sequence but share physicochemical characteristics like ...
Roel M Van Harten +2 more
exaly +7 more sources
Cathelicidins: Opportunities and Challenges in Skin Therapeutics and Clinical Translation [PDF]
AntibioticsCathelicidins are a group of cationic, amphipathic peptides that play a vital role in the innate immune response of many vertebrates, including humans.
Lenka DZUROVA, Jitka Frébortová
exaly +4 more sources
Snake Venom Cathelicidins as Natural Antimicrobial Peptides [PDF]
Frontiers in Pharmacology, 2019 Bioactive small molecules isolated from animals, plants, fungi and bacteria, including natural antimicrobial peptides, have shown great therapeutic potential worldwide.
Marlon Henrique Cardoso, Octavio Franco
exaly +6 more sources
Recent advances in the therapeutic potential of cathelicidins [PDF]
Frontiers in MicrobiologyThe alarming increase in antimicrobial resistance in the last decades has prompted the search for alternatives to control infectious diseases. Antimicrobial peptides (AMPs) represent a heterogeneous class of molecules with ample antibacterial, antiviral,
Maria Eduarda Souza Guerra +9 more
exaly +4 more sources
Marsupial cathelicidins: characterization, antimicrobial activity and evolution in this unique mammalian lineage [PDF]
Frontiers in ImmunologyIntroductionCathelicidins are a family of antimicrobial peptides well-known for their antimicrobial and immunomodulatory functions in eutherian mammals such as humans.
Emma Peel +7 more
doaj +2 more sources
Cathelicidins Limit Intracellular Neospora caninum-Infection in Macrophages [PDF]
PathogensInfections with the protozoan Neospora caninum cause abortion in cattle, likely due to the parasite’s replication and excessive inflammation in the placenta.
Franco Fiorani +5 more
doaj +2 more sources
Significance and Diagnostic Role of Antimicrobial Cathelicidins (LL-37) Peptides in Oral Health
Biomolecules, 2017 Cathelicidins are a group of oral antimicrobial peptides that play multiple vital roles in the human body, such as their antimicrobial (broad spectrum) role against oral microbes, wound healing, and angiogenesis, with recent evidences about their role in
Zohaib Khurshid +2 more
exaly +3 more sources
Exploring the Antimicrobial and Immunomodulatory Potential of Gecko-Derived Cathelicidin Gj-CATH5 [PDF]
BiomoleculesRegulating the innate immune response against infections, particularly drug-resistant bacteria, is a key focus in anti-infection therapy. Cathelicidins, found in vertebrates, are crucial for pathogen resistance.
Shasha Cai +3 more
doaj +2 more sources
Current Issues in Molecular Biology, 2021 The role of inflammatory mediators in dental pulp is unique. The local environment of pulp responds to any changes in the physiology that are highly fundamental, like odontoblast cell differentiation and other secretory activity.
Nireeksha,Shetty N,Nireeksha Shetty +2 more
exaly +3 more sources
Natural and Synthetic Peptides as Alternatives to Antibiotics in Intestinal Infections—A Review [PDF]
AntibioticsBackground/Objectives: Antimicrobial peptides (AMPs), evolutionarily conserved components of innate immunity characterized by their broad-spectrum efficacy and minimal resistance development, are increasingly recognized as promising therapeutic ...
Lala Stepanyan +9 more
doaj +2 more sources