Results 31 to 40 of about 5,375 (171)
mBio, 2016 The world is at the precipice of a postantibiotic era in which medical procedures and minor injuries can result in bacterial infections that are no longer effectively treated by antibiotics.
Cheng Kao +5 more
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Antibiotics, 2023 Antimicrobial peptides (AMPs) act directly on pathogens and maintain the anti-inflammatory effects and activation of immunocompetent cells. Therefore, the activation of the immune system in poultry via the elevation of endogenous AMPs has been attempted.
Takumi Ikeda +9 more
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Streptococcal M1 Strikes by Neutralizing Cathelicidins [PDF]
Cell Host & Microbe, 2015 Virulent group A streptococci have become a serious threat, with the emergence of the hypervirulent lineage M1T1. In this issue of Cell Host & Microbe, LaRock et al. (2015), uncover a role for the streptococcal M1 protein in neutralizing a key human antimicrobial peptide, cathelicidin.
Henriques-Normark, Birgitta +1 more
openaire +2 more sources
Frontiers in Immunology, 2020 This study aimed to characterize cathelicidins from the gray short-tailed opossum in silico and experimentally validate their antimicrobial effects against various pathogenic bacteria and West Nile virus (WNV).
Hye-sun Cho +11 more
doaj +1 more source
Cathelicidin deficiency predisposes to eczema herpeticum [PDF]
Journal of Allergy and Clinical Immunology, 2006 The cathelicidin family of antimicrobial peptides is an integral component of the innate immune response that exhibits activity against bacterial, fungal, and viral pathogens. Eczema herpeticum (ADEH) develops in a subset of patients with atopic dermatitis (AD) because of disseminated infection with herpes simplex virus (HSV).This study investigated ...
Michael D, Howell +8 more
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Scientific Reports, 2018 Cathelicidins play pivotal roles in host defense. The discovery of novel cathelicidins is important research; however, despite the identification of many cathelicidins in vertebrates, few have been reported in amphibians.
Xiaoqing Cao +10 more
doaj +1 more source
Human Cathelicidin Production by the Cervix
PLoS ONE, 2014 hCAP18/LL-37 is the sole human cathelicidin; a family of host defence peptides with key roles in innate host defence. hCAP18/LL-37 is expressed primarily by neutrophils and epithelial cells, but its production and function in the lower genital tract is largely uncharacterised.
Frew, Lorraine +7 more
openaire +6 more sources
Native Pig Neutrophil Products: Insights into Their Antimicrobial Activity
Microorganisms, 2023 Cationic antimicrobial peptides are molecules with potential applications for treating infections due to their antimicrobial and immunomodulatory properties.
Eric Fernández-De La Cruz +7 more
doaj +1 more source
Cathelicidin impact on inflammatory cells.
Central-European journal of immunology, 2015 Cathelicidins, like other antimicrobial peptides, exhibit direct antimicrobial activities against a broad spectrum of microbes, including both Gram-positive and Gram-negative bacteria, enveloped viruses, and fungi. These host-derived peptides kill the invaded pathogens by perturbing their cell membranes and can neutralize biological activities of ...
Agier, Justyna +2 more
openaire +3 more sources
Cathelicidin-derived antiviral peptide inhibits herpes simplex virus 1 infection
Frontiers in Microbiology, 2023 Herpes simplex virus 1 (HSV-1) is a widely distributed virus. HSV-1 is a growing public health concern due to the emergence of drug-resistant strains and the current lack of a clinically specific drug for treatment.
Xiaomin Guo +8 more
doaj +1 more source