Results 31 to 40 of about 6,173 (199)

Antimicrobial Activity of Cathelicidin-Derived Peptide from the Iberian Mole Talpa occidentalis

Vaccines, 2022
The immune systems of all vertebrates contain cathelicidins, a family of antimicrobial peptides. Cathelicidins are a type of innate immune effector that have a number of biological functions, including a well-known direct antibacterial action and ...
Andrea Otazo-Pérez, Patricia Asensio-Calavia, Sergio González-Acosta, Victoria Baca-González, Manuel R. López, Antonio Morales-delaNuez, José Manuel Pérez de la Lastra   +6 more
doaj   +1 more source

Tissue expression and developmental regulation of chicken cathelicidin antimicrobial peptides

Journal of Animal Science and Biotechnology, 2012
Cathelicidins are a major family of antimicrobial peptides present in vertebrate animals with potent microbicidal and immunomodulatory activities. Four cathelicidins, namely fowlicidins 1 to 3 and cathelicidin B1, have been identified in chickens.
Achanta Mallika, Sunkara Lakshmi T, Dai Gan, Bommineni Yugendar R, Jiang Weiyu, Zhang Guolong   +5 more
doaj   +1 more source

Differential Ability of Bovine Antimicrobial Cathelicidins to Mediate Nucleic Acid Sensing by Epithelial Cells [PDF]

, 2017
Cathelicidins encompass a family of cationic peptides characterized by antimicrobial activity and other functions, such as the ability to enhance the sensing of nucleic acids by the innate immune system. The present study aimed to investigate the ability
Arnaud Baumann, Kiener, Mirjam Susanna, Mirjam Susanna Kiener, Vincent Perreten, Artur Summerfield, Summerfield, Artur, Perreten, Vincent, Brendan Haigh, Baumann, Arnaud, Haigh, Brendan   +9 more
core   +1 more source

Therapeutic Role of Antimicrobial Peptides in Diabetes Mellitus

Biologics, 2022
Antimicrobial peptides (AMPs) have recently become widely publicized because they have the potential to function in alternative therapies as “natural” antibiotics, with their main advantage being a broad spectrum of activity.
Julia Depta, Paulina Małkowska, Monika Wysokińska, Karolina Todorska, Olga Sierawska, Rafał Hrynkiewicz, Dominika Bębnowska, Paulina Niedźwiedzka-Rystwej   +7 more
doaj   +1 more source

Evolution of the Primate Cathelicidin [PDF]

Journal of Biological Chemistry, 2006
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Zelezetsky, Igor, Pontillo, Alessandra, Puzzi, Luca, Antcheva, Nikolinka, Segat, Ludovica, Pacor, Sabrina, Crovella, Sergio, Tossi, Alessandro   +7 more
openaire   +2 more sources

Cathelicidin Antimicrobial Peptides with Reduced Activation of Toll-Like Receptor Signaling Have Potent Bactericidal Activity against Colistin-Resistant Bacteria

mBio, 2016
The world is at the precipice of a postantibiotic era in which medical procedures and minor injuries can result in bacterial infections that are no longer effectively treated by antibiotics.
Cheng Kao, Xiaoyan Lin, Guanghui Yi, Yunliang Zhang, Dean A. Rowe-Magnus, Karen Bush   +5 more
doaj   +1 more source

Molecular Cloning, Expression Analyses, and Physiological Roles of Cathelicidins in the Bursa of Fabricius of the Japanese Quail, Coturnix japonica

Antibiotics, 2023
Antimicrobial peptides (AMPs) act directly on pathogens and maintain the anti-inflammatory effects and activation of immunocompetent cells. Therefore, the activation of the immune system in poultry via the elevation of endogenous AMPs has been attempted.
Takumi Ikeda, Hirotada Kondo, Daiki Nunomura, Genki Sato, Machi Ito, Nanako Yamanaka, Shawichi Iwamuro, Itaru Hasunuma, Sakae Kikuyama, Tetsuya Kobayashi   +9 more
doaj   +1 more source

Human Cathelicidin Production by the Cervix

PLoS ONE, 2014
hCAP18/LL-37 is the sole human cathelicidin; a family of host defence peptides with key roles in innate host defence. hCAP18/LL-37 is expressed primarily by neutrophils and epithelial cells, but its production and function in the lower genital tract is largely uncharacterised.
Frew, Lorraine, Makieva, Sofia, McKinlay, Andrew T M, McHugh, Brian J, Doust, Ann, Norman, Jane E, Davidson, Donald J, Stock, Sarah J   +7 more
openaire   +6 more sources

Opossum Cathelicidins Exhibit Antimicrobial Activity Against a Broad Spectrum of Pathogens Including West Nile Virus

Frontiers in Immunology, 2020
This study aimed to characterize cathelicidins from the gray short-tailed opossum in silico and experimentally validate their antimicrobial effects against various pathogenic bacteria and West Nile virus (WNV).
Hye-sun Cho, Joori Yum, Andy Larivière, Nicolas Lévêque, Quy Van Chanh Le, ByeongYong Ahn, Hyoim Jeon, Kwonho Hong, Nagasundarapandian Soundrarajan, Jin-Hoi Kim, Charles Bodet, Chankyu Park   +11 more
doaj   +1 more source

Immunomodulatory Properties of Defensins and Cathelicidins [PDF]

, 2006
Host defence peptides are a conserved component of the innate immune response in all complex life forms. In humans, the major classes of host defence peptides include the alpha- and beta-defensins and the cathelicidin, hCAP-18/LL-37. These peptides are expressed in the granules of neutrophils and by a wide variety of tissue types.
Bowdish, D. M. E., Davidson, D. J., Hancock, R. E. W.   +2 more
openaire   +2 more sources