Results 11 to 20 of about 6,173 (199)
Cathelicidins Modulate TLR-Activation and Inflammation [PDF]
Cathelicidins are short cationic peptides that are part of the innate immune system. At first, these peptides were studied mostly for their direct antimicrobial killing capacity, but nowadays they are more and more appreciated for their immunomodulatory ...
Maaike R. Scheenstra +5 more
doaj +7 more sources
Antiviral Potential of Cathelicidins [PDF]
The global burden of morbidity and mortality arising from viral infections is high; however, the development of effective therapeutics has been slow. As our understanding of innate immunity has expanded over recent years, knowledge of natural host defenses against viral infections has started to offer potential for novel therapeutic strategies.
Barlow, Peter G. +3 more
core +6 more sources
Chicken cathelicidins display antimicrobial activity against multiresistant bacteria without inducing strong resistance. [PDF]
The increased prevalence of multidrug-resistant (MDR) bacteria in combination with the relatively limited development of new antibiotics presents a serious threat to public health.
Edwin J A Veldhuizen +3 more
doaj +3 more sources
Cathelicidins are an important family of antimicrobial peptide effectors of innate immunity in vertebrates. While their mammalian counterparts have been extensively characterized in the last two decades, data on fish cathelicidins has only recently been ...
Marco Scocchi +3 more
openaire +2 more sources
Cathelicidins - Natures Attempt at Combinatorial Chemistry
Cathelicidins are a family of diverse antimicrobial peptides found in granules of mammalian neutrophils. Cathelicidins are active against a broad range of microbes in different environments. Aside from their antimicrobial activity, cathelicidins possess other biological properties including cytotoxic activity towards mammalian cells.
Ole E, Sorensen, Niels, Borregaard
core +4 more sources
Cathelicidins in the Tasmanian devil (Sarcophilus harrisii) [PDF]
AbstractTasmanian devil joeys, like other marsupials, are born at a very early stage of development, prior to the development of their adaptive immune system, yet survive in a pathogen-laden pouch and burrow. Antimicrobial peptides, called cathelicidins, which provide innate immune protection during early life, are expressed in the pouch lining, skin ...
Peel, E. +5 more
openaire +6 more sources
Cathelicidins constitute important antimicrobial peptides of innate immunity. In order to elucidate the evolutionary history of cathelicidins, the author performed comprehensive phylogenetic analyses of cathelicidin homologs in all available genomes including those completed recently. The organization of cathelicidin genes, as well as the secondary and
Pavlopoulou, Athanasia
openaire +3 more sources
Cathelicidins In Humans And Animals [PDF]
Cathelicidins are Important immunological peptides – HDPs (Host Defense Peptides) with high biological activity in mammals, including human and vertebrate animals.
Deptuła Jakub +4 more
doaj +2 more sources
Endometritis is a common bacterial disease of dairy cows. Cathelicidins are host-defense peptides that play important roles in clearance of bacteria. However, the expression pattern of these peptides during endometritis is still unclear.
Yajuan Li +6 more
doaj +1 more source
Cathelicidins are potent antimicrobial peptides with broad spectrum antimicrobial activity in many vertebrates and an important component of the innate immune system.
Munjeong Choi +5 more
doaj +1 more source

