Results 11 to 20 of about 3,232 (162)

Cathelicidins Modulate TLR-Activation and Inflammation [PDF]

Frontiers in Immunology, 2020
Cathelicidins are short cationic peptides that are part of the innate immune system. At first, these peptides were studied mostly for their direct antimicrobial killing capacity, but nowadays they are more and more appreciated for their immunomodulatory ...
Henk P. Haagsman, Haagsman, HP, Coorens, M, Edwin J. A. Veldhuizen, Scheenstra, MR, Roel M. van Harten, Veldhuizen, EJA, Maarten Coorens, van, Harten RM, Maaike R. Scheenstra   +9 more
core   +4 more sources

Genomewide Analysis and Biological Characterization of Cathelicidins with Potent Antimicrobial Activity and Low Cytotoxicity from Three Bat Species

Antibiotics, 2022
Cathelicidins are potent antimicrobial peptides with broad spectrum antimicrobial activity in many vertebrates and an important component of the innate immune system.
Ahn, Byeongyong, Hye-sun Cho, Munjeong Choi, Byeongyong Ahn, Chankyu Park, Nagasundarapandian, Soundrarajan, Soundrarajan Nagasundarapandian, Cho, Hye-sun, Prathap, Somasundaram, Choi, Munjeong, Park, Chankyu, Somasundaram Prathap   +11 more
core   +2 more sources

Marsupial cathelicidins: characterization, antimicrobial activity and evolution in this unique mammalian lineage [PDF]

Frontiers in Immunology
IntroductionCathelicidins are a family of antimicrobial peptides well-known for their antimicrobial and immunomodulatory functions in eutherian mammals such as humans.
Katherine Belov, Emma Peel, Adele Gonsalvez, Carolyn J. Hogg   +3 more
core   +3 more sources

Diversity, Antimicrobial Action and Structure-Activity Relationship of Buffalo Cathelicidins

PLoS ONE, 2015
Cathelicidins are an ancient class of antimicrobial peptides (AMPs) with broad spectrum bactericidal activities. In this study, we investigated the diversity and biological activity of cathelicidins of buffalo, a species known for its disease resistance.
Mahesh Chandra Patra (472653), Sachinandan De (255914), Purusottam Mishra, Sourav Mahanty, Satyanagalakshmi Karri, Sachinandan De, Krishna Mohan Poluri (546021), Meenu Chopra (705199), Bidhan Chandra De, Satyanagalakshmi Karri (837997), Purusottam Mishra (527502), Sushil Kumar, Sourav Mahanty (527505), Kiran Thakur, Mahesh Chandra Patra, Krishna Mohan Poluri, Tirtha Kumar Datta, Meenu Chopra, Biswajit Brahma (527500), Tirtha Kumar Datta (527506), Bidhan Chandra De (527504), Sushil Kumar (197871), Kiran Thakur (459601), Datta Tirtha Kumar, Biswajit Brahma, Mishra Purusottam, De Bidhan Chandra, Chopra Meenu, Poluri Krishna Mohan, Kumar Sushil, Karri Satyanagalakshmi, Mahanty Sourav, Thakur Kiran, De Sachinandan, Brahma Biswajit, Patra Mahesh Chandra   +35 more
core   +2 more sources

Evidence of an antimicrobial-immunomodulatory role of Atlantic salmon cathelicidins during infection with Yersinia ruckeri [PDF]

PLoS ONE, 2011
Cathelicidins are a family of antimicrobial peptides that act as effector molecules of the innate immune system with broadspectrum antimicrobial properties.
Andrew Bridle (14732428), Nosworthy, E (15543518), Barbara Nowak (14745646), Polinski, M (15543521)   +3 more
core   +2 more sources

Expression Pattern of Cathelicidins in Dairy Cows During Endometritis and Role of Bovine Endometrial Epithelial Cells in Production of Cathelicidins

Frontiers in Veterinary Science, 2021
Endometritis is a common bacterial disease of dairy cows. Cathelicidins are host-defense peptides that play important roles in clearance of bacteria. However, the expression pattern of these peptides during endometritis is still unclear.
Yajuan Li, Yajuan Li, Xiaoyu Ma, Jie Yang, Xiaohu Wu, Zuoting Yan, Baoxiang He   +6 more
doaj   +1 more source

Antiviral potential of cathelicidins [PDF]

, 2014
The global burden of morbidity and mortality arising from viral infections is high; however, the development of effective therapeutics has been slow.
Davidson, Donald J, Barlow, Peter G, Gwyer Findlay, Emily, Findlay, Emily Gwyer, Currie, Silke M, Davidson, D.J., Barlow, Peter G., Findlay, E.G., Currie, S.M.   +8 more
core   +2 more sources

Cathelicidins Induce Toll-Interacting Protein Synthesis to Prevent Apoptosis in Colonic Epithelium

Journal of Innate Immunity, 2022
Cathelicidin peptides secreted by leukocytes and epithelial cells are microbicidal but also regulate pathogen sensing via toll-like receptors (TLRs) in the colon by mechanisms that are not fully understood.
Ravi Holani, Chathurika Rathnayaka, Graham A.D. Blyth, Anshu Babbar, Priyoshi Lahiri, Daniel Young, Antoine Dufour, Morley D. Hollenberg, Derek M. McKay, Eduardo R. Cobo   +9 more
doaj   +1 more source

Chicken cathelicidins display antimicrobial activity against multiresistant bacteria without inducing strong resistance. [PDF]

PLoS ONE, 2013
The increased prevalence of multidrug-resistant (MDR) bacteria in combination with the relatively limited development of new antibiotics presents a serious threat to public health.
Edwin J A Veldhuizen, Ellen C Brouwer, Viktoria A F Schneider, Ad C Fluit   +3 more
doaj   +1 more source

Tasmanian devil cathelicidins exhibit anticancer activity against Devil Facial Tumour Disease (DFTD) cells

Scientific Reports, 2023
The Tasmanian devil (Sarcophilus harrisii) is endangered due to the spread of Devil Facial Tumour Disease (DFTD), a contagious cancer with no current treatment options.
Cleopatra Petrohilos, Amanda Patchett, Carolyn J. Hogg, Katherine Belov, Emma Peel   +4 more
doaj   +1 more source