Results 11 to 20 of about 5,375 (171)

Cathelicidins Modulate TLR-Activation and Inflammation [PDF]

open access: yesFrontiers in Immunology, 2020
Cathelicidins are short cationic peptides that are part of the innate immune system. At first, these peptides were studied mostly for their direct antimicrobial killing capacity, but nowadays they are more and more appreciated for their immunomodulatory ...
Maaike R. Scheenstra   +5 more
doaj   +5 more sources

Cathelicidins In Humans And Animals [PDF]

open access: yesPostępy Mikrobiologii, 2019
Cathelicidins are Important immunological peptides – HDPs (Host Defense Peptides) with high biological activity in mammals, including human and vertebrate animals.
Deptuła Jakub   +4 more
doaj   +2 more sources

Effects of Virus-associated Molecular Patterns on the Expression of Cathelicidins in the Hen Vagina

open access: yesJournal of Poultry Science, 2016
The aim of this study was to examine the expression profiles of the cathelicidins (CATHs) in the oviduct and the effects of Toll-like receptor (TLR) ligands of virus-associated molecular patterns on CATHs expression in the vagina of hens.
Naoki Isobe, Yukinori Yoshimura
exaly   +3 more sources

Expression Pattern of Cathelicidins in Dairy Cows During Endometritis and Role of Bovine Endometrial Epithelial Cells in Production of Cathelicidins

open access: yesFrontiers in Veterinary Science, 2021
Endometritis is a common bacterial disease of dairy cows. Cathelicidins are host-defense peptides that play important roles in clearance of bacteria. However, the expression pattern of these peptides during endometritis is still unclear.
Yajuan Li   +6 more
doaj   +1 more source

Genomewide Analysis and Biological Characterization of Cathelicidins with Potent Antimicrobial Activity and Low Cytotoxicity from Three Bat Species

open access: yesAntibiotics, 2022
Cathelicidins are potent antimicrobial peptides with broad spectrum antimicrobial activity in many vertebrates and an important component of the innate immune system.
Munjeong Choi   +5 more
doaj   +1 more source

Antiviral Potential of Cathelicidins [PDF]

open access: yesFuture Microbiology, 2013
 The global burden of morbidity and mortality arising from viral infections is high; however, the development of effective therapeutics has been slow. As our understanding of innate immunity has expanded over recent years, knowledge of natural host defenses against viral infections has started to offer potential for novel therapeutic strategies.
Barlow, Peter G.   +3 more
openaire   +4 more sources

Molecular characterization, mRNA gene expression, and antimicrobial activity of 2 new cathelicidin genes in goose

open access: yesPoultry Science, 2020
Cathelicidins represent a major group of host defense peptides (HDPs) that share a highly conserved cathelin-like domain. In birds, this gene family has been identified in many species. However, no information was available in the goose until now.
Yingping Xiao   +6 more
doaj   +1 more source

Chicken cathelicidins display antimicrobial activity against multiresistant bacteria without inducing strong resistance. [PDF]

open access: yesPLoS ONE, 2013
The increased prevalence of multidrug-resistant (MDR) bacteria in combination with the relatively limited development of new antibiotics presents a serious threat to public health.
Edwin J A Veldhuizen   +3 more
doaj   +1 more source

The role of the host—Neutrophil biology

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple   +4 more
wiley   +1 more source

Cathelicidins Induce Toll-Interacting Protein Synthesis to Prevent Apoptosis in Colonic Epithelium

open access: yesJournal of Innate Immunity, 2022
Cathelicidin peptides secreted by leukocytes and epithelial cells are microbicidal but also regulate pathogen sensing via toll-like receptors (TLRs) in the colon by mechanisms that are not fully understood.
Ravi Holani   +9 more
doaj   +1 more source

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