Results 21 to 30 of about 5,375 (171)

Entamoeba histolytica Induces Intestinal Cathelicidins but Is Resistant to Cathelicidin-Mediated Killing [PDF]

open access: yesInfection and Immunity, 2012
ABSTRACTThe enteric protozoan parasiteEntamoeba histolyticais the cause of potentially fatal amebic colitis and liver abscesses.E. histolyticatrophozoites colonize the colon, where they induce inflammation, penetrate the mucosa, and disrupt the host immune system. The early establishment ofE.
Eduardo R, Cobo   +7 more
openaire   +2 more sources

Tasmanian devil cathelicidins exhibit anticancer activity against Devil Facial Tumour Disease (DFTD) cells

open access: yesScientific Reports, 2023
The Tasmanian devil (Sarcophilus harrisii) is endangered due to the spread of Devil Facial Tumour Disease (DFTD), a contagious cancer with no current treatment options.
Cleopatra Petrohilos   +4 more
doaj   +1 more source

Dodecapeptide Cathelicidins of Cetartiodactyla: Structure, Mechanism of Antimicrobial Action, and Synergistic Interaction With Other Cathelicidins [PDF]

open access: yesFrontiers in Microbiology, 2021
In this study, dodecapeptide cathelicidins were shown to be widespread antimicrobial peptides among the Cetruminantia clade. In particular, we investigated the dodecapeptide from the domestic goat Capra hircus, designated as ChDode and its unique ortholog from the sperm whale Physeter catodon (PcDode).
Ilia A. Bolosov   +12 more
openaire   +3 more sources

Snake cathelicidin from Bungarus fasciatus is a potent peptide antibiotics. [PDF]

open access: yesPLoS ONE, 2008
BACKGROUND: Cathelicidins are a family of antimicrobial peptides acting as multifunctional effector molecules of innate immunity, which are firstly found in mammalians. Recently, several cathelicidins have also been found from chickens and fishes.
Yipeng Wang   +8 more
doaj   +1 more source

Expression and activity of a novel cathelicidin from domestic cats. [PDF]

open access: yesPLoS ONE, 2011
Cathelicidins are small cationic antimicrobial peptides found in many species including primates, mammals, marsupials, birds and even more primitive vertebrates, such as the hagfish.
Brian C Leonard   +6 more
doaj   +1 more source

Antimicrobial Activity of Cathelicidin-Derived Peptide from the Iberian Mole Talpa occidentalis

open access: yesVaccines, 2022
The immune systems of all vertebrates contain cathelicidins, a family of antimicrobial peptides. Cathelicidins are a type of innate immune effector that have a number of biological functions, including a well-known direct antibacterial action and ...
Andrea Otazo-Pérez   +6 more
doaj   +1 more source

Cathelicidins and the Onset of Labour [PDF]

open access: yesScientific Reports, 2019
AbstractPreterm birth, defined as delivery before 37 weeks of gestation, is the leading cause of neonatal mortality and morbidity. Infection and inflammation are frequent antecedents of spontaneous preterm birth. Cathelicidin, an antimicrobial host defence peptide, is induced by infection and inflammation and although expressed in the reproductive ...
Sara R. van Boeckel   +11 more
openaire   +6 more sources

Tissue expression and developmental regulation of chicken cathelicidin antimicrobial peptides

open access: yesJournal of Animal Science and Biotechnology, 2012
Cathelicidins are a major family of antimicrobial peptides present in vertebrate animals with potent microbicidal and immunomodulatory activities. Four cathelicidins, namely fowlicidins 1 to 3 and cathelicidin B1, have been identified in chickens.
Achanta Mallika   +5 more
doaj   +1 more source

Therapeutic Role of Antimicrobial Peptides in Diabetes Mellitus

open access: yesBiologics, 2022
Antimicrobial peptides (AMPs) have recently become widely publicized because they have the potential to function in alternative therapies as “natural” antibiotics, with their main advantage being a broad spectrum of activity.
Julia Depta   +7 more
doaj   +1 more source

Genetic diversity of Japanese quail cathelicidins

open access: yesPoultry Science, 2021
Japanese quail is a low-fat, meat-bird species exhibiting high disease resistance. Cathelicidins (CATHs) are host defense peptides conserved across numerous vertebrate species that play an important role in innate immunity. The activity of host defense peptides can be affected by amino acid substitutions.
Taichiro Ishige   +4 more
openaire   +3 more sources

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