Results 41 to 50 of about 6,173 (199)
Cathelicidin impact on inflammatory cells
Cathelicidins, like other antimicrobial peptides, exhibit direct antimicrobial activities against a broad spectrum of microbes, including both Gram-positive and Gram-negative bacteria, enveloped viruses, and fungi. These host-derived peptides kill the invaded pathogens by perturbing their cell membranes and can neutralize biological activities of ...
Agier, Justyna +2 more
openaire +2 more sources
Cathelicidins play pivotal roles in host defense. The discovery of novel cathelicidins is important research; however, despite the identification of many cathelicidins in vertebrates, few have been reported in amphibians.
Xiaoqing Cao +10 more
doaj +1 more source
Native Pig Neutrophil Products: Insights into Their Antimicrobial Activity
Cationic antimicrobial peptides are molecules with potential applications for treating infections due to their antimicrobial and immunomodulatory properties.
Eric Fernández-De La Cruz +7 more
doaj +1 more source
Streptococcal M1 Strikes by Neutralizing Cathelicidins [PDF]
Virulent group A streptococci have become a serious threat, with the emergence of the hypervirulent lineage M1T1. In this issue of Cell Host & Microbe, LaRock et al. (2015), uncover a role for the streptococcal M1 protein in neutralizing a key human antimicrobial peptide, cathelicidin.
Henriques-Normark, Birgitta +1 more
openaire +2 more sources
Cathelicidin-derived antiviral peptide inhibits herpes simplex virus 1 infection
Herpes simplex virus 1 (HSV-1) is a widely distributed virus. HSV-1 is a growing public health concern due to the emergence of drug-resistant strains and the current lack of a clinically specific drug for treatment.
Xiaomin Guo +8 more
doaj +1 more source
Expression of Cathelicidin in Human Salivary Glands [PDF]
Salivary secretions play a critical role in maintaining oral health via innate host defense mechanisms and secretion of secretory IgA. One of the antimicrobial peptides, LL-37, is the only cathelicidin protein that has yet been identified in humans. Cathelicidins are a family of peptides thought to provide an innate defensive barrier against a variety ...
Jeong-Su, Woo +5 more
openaire +2 more sources
Cathelicidins, a class of gene-encoded effector molecules of vertebrate innate immunity, provide a first line of defense against microbial invasions. Although cathelicidins from mammals, birds, reptiles and fishes have been extensively studied, little is
Guiying Ling +6 more
doaj +1 more source
Sequence alignment of cathelicidins.
(A) Multi-sequence alignment of cathelicidin-RCs with other representative cathelicidins. (B) Alignment of the amphibian cathelicidins identified so far from A. loloensisi, P. yunnanensis, L. fragilis and R. catesbeiana.
Guiying Ling (543925) +6 more
core +1 more source
Streptococcus pneumoniae is a leading cause of pneumonia mortality globally. Pneumococcal disease is often associated with prolonged colonisation of hosts and this process is facilitated by biofilm formation that is largely resistant to conventional ...
Michael T. Boswell, Riana Cockeran
doaj +1 more source
cDNA sequences of three sheep myeloid cathelicidins
Several myeloid antimicrobial peptide precursors have been shown to consist of a N-terminal proregion similar to a protein named cathelin and a structurally varied C-terminal antimicrobial domain.
SCOCCHI M +2 more
core +2 more sources

