Results 41 to 50 of about 3,232 (162)

Porcine cathelicidins efficiently complex and deliver nucleic acids to plasmacytoid dendritic cells and can thereby mediate bacteria-induced IFN-α responses. [PDF]

, 2014
Cathelicidins constitute potent antimicrobial peptides characterized by a high cationic charge that enables strong interactions with nucleic acids.
Python, Sylvie, Demoulins, Thomas, Summerfield, Artur, Baumann, Arnaud, Python S, Baumann A, Démoulins T, Summerfield A   +7 more
core   +1 more source

Avian cathelicidins: Paradigms for the development of anti-infectives

, 2011
The broad-spectrum defense system based on host defense peptides (HDPs) is evolutionary very old and many invertebrates rely on this system for protection from bacterial infections.
Molhoek, E.M., Dijk, A. van, Bikker, F.J., Veldhuizen, E.J.A., Haagsman, H.P., Yu, P.L.   +5 more
core   +2 more sources

Cathelicidin-derived antiviral peptide inhibits herpes simplex virus 1 infection

Frontiers in Microbiology, 2023
Herpes simplex virus 1 (HSV-1) is a widely distributed virus. HSV-1 is a growing public health concern due to the emergence of drug-resistant strains and the current lack of a clinically specific drug for treatment.
Xiaomin Guo, Yanxing An, Wanmin Tan, Ling Ma, Mingyang Wang, Juyan Li, Binghong Li, Wei Hou, Li Wu   +8 more
doaj   +1 more source

Antiviral activity of selected cathelicidins against infectious bronchitis virus [PDF]

, 2022
Avian infectious bronchitis (IB) is a highly contagious disease caused by infectious bronchitis virus (IBV), a coronavirus of domestic fowl. IB is a major concern in the poultry industry, causing worldwide economic losses through decreased egg production
M. Hélène Verheije, Berends, Alinda J., Albert van Dijk, Weerts, Erik A.W.S., van Beurden, Steven J., Kooij, Jannetje, Ordonez, Soledad R., Haagsman, Henk P., Soledad R. Ordonez, Marloes Angel, Henk P. Haagsman, Coorens, Maarten, Angel, Marloes, Erik A. W. S. Weerts, van Harten, Roel M., Jannetje Kooij, van Dijk, Albert, Edwin J. A. Veldhuizen, Roel M. van Harten, Veldhuizen, Edwin J.A., Steven J. van Beurden, Maarten Coorens, Verheije, M. Hélène, Alinda J. Berends, dI&I I&I-1, dI&I I&I-3, dPB I&I, VP pathologie, Immunologie, LS Moleculaire Afweer, LS Pathologie, VPDC pathologie, Afd Pharmacology, Moleculaire afweer   +33 more
core   +1 more source

Effect of antimicrobial peptides on planktonic growth, biofilm formation and biofilm-derived bacterial viability of Streptococcus pneumoniae

Southern African Journal of Infectious Diseases, 2021
Streptococcus pneumoniae is a leading cause of pneumonia mortality globally. Pneumococcal disease is often associated with prolonged colonisation of hosts and this process is facilitated by biofilm formation that is largely resistant to conventional ...
Michael T. Boswell, Riana Cockeran
doaj   +1 more source

Supplementary Material for: Cathelicidins Induce Toll-Interacting Protein Synthesis to Prevent Apoptosis in Colonic Epithelium

, 2022
Cathelicidin peptides secreted by leukocytes and epithelial cells are microbicidal but also regulate pathogen sensing via toll-like receptors (TLRs) in the colon by mechanisms that are not fully understood.
Lahiri P. (13809018), Holani R. (13809014), Rathnayaka C. (13809015), McKay D.M. (13809022), Blyth G.A.D. (13809016), Dufour A. (13809020), Babbar A. (13809017), Young D. (13809019), Hollenberg M.D. (13809021), Cobo E.R. (13809023)   +9 more
core   +1 more source

Ciprofloxacin Affects Host Cells by Suppressing Expression of the Endogenous Antimicrobial Peptides Cathelicidins and Beta-Defensin-3 in Colon Epithelia

Antibiotics, 2014
Antibiotics exert several effects on host cells including regulation of immune components. Antimicrobial peptides (AMPs), e.g., cathelicidins and defensins display multiple functions in innate immunity.
Protim Sarker, Akhirunnesa Mily, Abdullah Al Mamun, Shah Jalal, Peter Bergman, Rubhana Raqib, Gudmundur H. Gudmundsson, Birgitta Agerberth   +7 more
doaj   +1 more source

Tammar wallaby mammary cathelicidins are differentially expressed during lactation and exhibit antimicrobial and cell proliferative activity

, 2011
Cathelicidins secreted in milk may be central to autocrine feedback in the mammary gland for optimal development in addition to conferring innate immunity to both the mammary gland and the neonate.
Stephen S. Wanyonyi, Kevin R. Nicholas, Lefevre, Christophe, Wanyonyi, Stephen S., Sharp, Julie A., Nicholas, Kevin R., Julie A. Sharp, Christophe Lefevre, Elie Khalil, Khalil, Elie   +9 more
core   +1 more source

Cathelicidins In Humans And Animals

Postępy Mikrobiologii, 2019
Cathelicidins are Important immunological peptides – HDPs (Host Defense Peptides) with high biological activity in mammals, including human and vertebrate animals.
Deptuła Jakub, Tokarz-Deptuła Beata, Malinowska-Borysiak Magdalena, Stosik Michał, Deptuła Wiesław   +4 more
doaj   +1 more source

Past, Present, and Future of Naturally Occurring Antimicrobials Related to Snake Venoms

Animals, 2023
This review focuses on proteins and peptides with antimicrobial activity because these biopolymers can be useful in the fight against infectious diseases and to overcome the critical problem of microbial resistance to antibiotics.
Nancy Oguiura, Leonardo Sanches, Priscila V. Duarte, Marcos A. Sulca-López, Maria Terêsa Machini   +4 more
doaj   +1 more source