Results 61 to 70 of about 5,375 (171)

Maternal Dietary Inflammatory Index and Biomarkers of Inflammation at Birth

Maternal &Child Nutrition, EarlyView.
ABSTRACT We evaluated the association between the inflammatory potential of the maternal diet during pregnancy and levels of inflammatory biomarkers measured in cord blood and maternal serum at birth. Dietary inflammatory potential was calculated using the energy‐adjusted dietary inflammatory index (E‐DII) in the French EDEN and ELFE birth cohorts ...
Courtney Dow, Rosalie Delvert, Blandine de Lauzon‐Guillain, Judith van der Waerden, Laetitia Davidovic, Olfa Khalfallah, Susana Barbosa, Marie‐Aline Charles, Cédric Galera, Barbara Heude   +9 more
wiley   +1 more source

Cathelicidin Peptides Restrict Bacterial Growth via Membrane Perturbation and Induction of Reactive Oxygen Species

mBio, 2019
All metazoans produce antimicrobial peptides (AMPs) that have both broad antimicrobial and immunomodulatory activity. Cathelicidins are AMPs that preferentially kill Gram-negative bacteria in vitro, purportedly by assembling into higher-order structures ...
Dean A. Rowe-Magnus, Adenine Y. Kao, Antonio Cembellin Prieto, Meng Pu, Cheng Kao   +4 more
doaj   +1 more source

Evaluation of the Cutaneous Immunological Milieu Before and After Treatment With Meglumine Antimoniate in Dogs Naturally Affected by Leishmaniosis due to Leishmania infantum

Veterinary Dermatology, EarlyView.
Background: Canine leishmaniosis (CanL) is a zoonotic disease of variable severity. The typical immune response is driven by an exaggerated humoral immune response. Protective immunity is mediated by pro‐inflammatory cytokines that enhance macrophage leishmanicidal activity. Objective: To evaluate the cutaneous and the systemic immune responses as well
M. Platenik, A. Di Loria, L. Archer, M. Saridomichelakis, A. S. Benvenuto, D. Santoro   +5 more
wiley   +1 more source

Immune endotypes in tuberculosis: Keys to decoding disease complexity

Journal of Internal Medicine, Volume 299, Issue 6, Page 670-693, June 2026.
Abstract Tuberculosis (TB) remains a major global health challenge, with multi‐drug antibiotic regimens as the current standard of care. While effective at killing Mycobacterium tuberculosis, these treatments do not resolve persistent inflammation, prevent lung damage, or reverse immune dysregulation that contribute to poor outcomes and disease ...
Shamila D. Alipoor, Julia Guthrie, Lina Davies Forsman, Andrew R. Di Nardo, Susanna Brighenti   +4 more
wiley   +1 more source

Bactericidal Activity of Mammalian Cathelicidin-Derived Peptides [PDF]

Infection and Immunity, 2000
ABSTRACT Endogenous antimicrobial peptides of the cathelicidin family contribute to innate immunity. The emergence of widespread antibiotic resistance in many commonly encountered bacteria requires the search for new bactericidal agents with therapeutic potential. Solid-phase synthesis was employed to prepare linear antimicrobial
S M, Travis, N N, Anderson, W R, Forsyth, C, Espiritu, B D, Conway, E P, Greenberg, P B, McCray, R I, Lehrer, M J, Welsh, B F, Tack   +9 more
openaire   +2 more sources

Imaging the Antistaphylococcal Activity of CATH-2: Mechanism of Attack and Regulation of Inflammatory Response

mSphere, 2017
Chicken cathelicidin-2 (CATH-2) is a broad-spectrum antimicrobial host defense peptide (HDP) that may serve as a paradigm for the development of new antimicrobial agents.
Viktoria A. F. Schneider, Maarten Coorens, Johanna L. M. Tjeerdsma-van Bokhoven, George Posthuma, Albert van Dijk, Edwin J. A. Veldhuizen, Henk P. Haagsman   +6 more
doaj   +1 more source

Analysis of the effect of polymorphisms within the CATHL7 gene on dairy performance parameters

Journal of Veterinary Research, 2023
Antimicrobial peptides, including cathelicidins, play a significant role in farm animals, influencing animal welfare, immunity, and thus the quality of animal products.
Hiller Sonia, Kowalewska Inga, Czerniawska-Piątkowska Ewa, Banaszewska Dorota   +3 more
doaj   +1 more source

Cathelicidins in the Tasmanian devil (Sarcophilus harrisii) [PDF]

Scientific Reports, 2016
AbstractTasmanian devil joeys, like other marsupials, are born at a very early stage of development, prior to the development of their adaptive immune system, yet survive in a pathogen-laden pouch and burrow. Antimicrobial peptides, called cathelicidins, which provide innate immune protection during early life, are expressed in the pouch lining, skin ...
Peel, E., Cheng, Y., Djordjevic, J. T., Fox, S., Sorrell, T. C., Belov, K.   +5 more
openaire   +3 more sources

The immunomodulatory effect of cathelicidin-B1 on chicken macrophages

Veterinary Research, 2020
Cathelicidins (CATHs) play an important role in the innate immune response against microbial infections. Among the four chicken cathelicidins, CATH-B1 is studied the least.
Lianci Peng, Maaike R. Scheenstra, Roel M. van Harten, Henk P. Haagsman, Edwin J. A. Veldhuizen   +4 more
doaj   +1 more source

Targeting of Gut Microbiota by Bioactive Peptides for the Improvement of Metabolic Diseases: A Review

Food Frontiers, Volume 7, Issue 3, May 2026.
Bioactive peptides (BPs) derived from dietary proteins modulate the gut microbiotametabolism axis by reshaping microbial composition and regulating key metabolites, including short‐chain fatty acids. BPs also enhance intestinal barrier integrity and immune homeostasis, thereby reducing inflammation.
Jiao Li, Yongchao Chen, Zhihua Li, Gang Liu, Hongmei Jiang, Jun Fang, Sujuan Ding   +6 more
wiley   +1 more source