Results 81 to 90 of about 3,232 (162)

Novel cathelicidins in horse leukocytes

, 1999
Cathelicidins are precursors of defense peptides of the innate immunity and are widespread in mammals. Their structure comprises a conserved prepropiece and an antimicrobial domain that is structurally varied both intra- and inter-species.
BOSCOLO S., ZANETTI, Margherita, SCOCCHI M., GIULOTTO E., Tomasinsig L., BONTEMPO D., Zanetti M., Marco Scocchi, Margherita Zanetti, Daniela Bontempo, Elena Giulotto, Linda Tomasinsig, Sabrina Boscolo, GIULOTTO, ELENA   +13 more
core   +2 more sources

Role of Cathelicidins in Atherosclerosis and Associated Cardiovascular Diseases

Journal of Molecular Pathology
Cathelicidins (human LL-37 and rat CRAMP) are multifunctional peptides involved in various cardiovascular conditions. This review integrates the recent findings about the functional involvement of LL-37/CRAMP across atherosclerosis, acute coronary ...
Siarhei A. Dabravolski, Nikolay A. Orekhov, Alexey V. Churov, Irina A. Starodubtseva, Dmitry F. Beloyartsev, Tatiana I. Kovyanova, Vasily N. Sukhorukov, Alexander N. Orekhov   +7 more
doaj   +1 more source

Cathelicidins positively regulate pancreatic beta-cell functions

, 2016
Cathelicidins are pleiotropic antimicrobial peptides largely described for innate antimicrobial defenses and, more recently, immunomodulation. They are shown to modulate a variety of immune or nonimmune host cell responses. However, how cathelicidins are
Gudmundsson, Gudmundur H.,, Xu, Meng,, Ortsäter, Henrik,, Lundeberg, Erik,, Agerberth, Birgitta,, Haeggström, Jesper Z.,, Diana, Julien,, Sun, Jia,, Chen, Yong Q.,, Juntti-Berggren, Lisa,, Lundeberg, E, Chen, YQ, Juntti-Berggren, L, Sun, J, Haeggstrom, JZ, Xu, M, Ortsater, H, Gudmundsson, GH, Agerberth, B,, Diana, J   +19 more
core   +1 more source

Modulation of outer membrane vesicle-based immune responses by cathelicidins [PDF]

, 2022
Antibiotic resistance is increasing and one strategy to prevent resistance development is the use of bacterial vaccines. For Gram-negative bacteria, natural outer membrane vesicles (OMVs) could be used for vaccine development.
Versluis, Chantal M, van Grondelle, Monica O, Veldhuizen, Edwin J A, Haagsman, Henk P, Balhuizen, Melanie D, dI&I I&I-3, Moleculaire afweer, Immunologie, Sub Biomol.Mass Spectrometry & Proteom.   +8 more
core  

No difference in inflammatory mediator expression between mast cell-rich and mast cell-poor rosacea lesions in Korean patients: a comparative study [PDF]

The Ewha Medical Journal
Objectives: This study aimed to evaluate the correlation between mast cell (MC) density in rosacea-affected skin and the expression of key inflammatory mediators, including IL-6, TNF-α, and cathelicidin LL-37.
Jin Ju Lee, Bo Ram Kwon, Min Young Lee, Ji Yeon Byun, Joo Young Roh, Hae Young Choi, You Won Choi   +6 more
doaj   +1 more source

In vitro activity of human and animal cathelicidins against livestock-associated methicillin-resistant Staphylococcus aureus

, 2015
Livestock-associated methicillin-resistant S. aureus (LA-MRSA) is an important zoonotic pathogen. An emerging problem in treating S. aureus infections is the increasing resistance against antibiotics. A possible way to overcome this issue is to boost the
Schwarz, Stefan, von Köckritz-Blickwede, M., Kadlec, Kristina, Blodkamp, Stefanie, Gutsmann, T., Naim, H.Y.   +5 more
core   +1 more source

Peptides from the Pouch: Marsupial and Monotreme Cathelicidins

, 2018
The rise in antimicrobial resistance and paucity of new antimicrobial compounds calls for alternatives to traditional antibiotics. Antimicrobial peptides (AMPs) have emerged as potential candidates.
Peel, Emma Jane
core  

Influence of maternal nutrition and one-carbon metabolites supplementation on bovine antimicrobial peptides in fetal and maternal tissues

Frontiers in Veterinary Science
IntroductionMaternal nutrition during pregnancy critically influences offspring development and immune function. One-carbon metabolites (OCM) are epigenetic modifiers that may modulate antimicrobial peptide (AMP) expression, which is vital for innate ...
Mojtaba Daneshi, Pawel P. Borowicz, Mara R. Hirchert, Yssi L. Entzie, Jessica G. Syring, Layla E. King, Kazi Sarjana Safain, Muhammad Anas, Lawrence P. Reynolds, Alison K. Ward, Carl R. Dahlen, Matthew S. Crouse, Joel S. Caton   +12 more
doaj   +1 more source

Natural and Synthetic Peptides as Alternatives to Antibiotics in Intestinal Infections—A Review

Antibiotics
Background/Objectives: Antimicrobial peptides (AMPs), evolutionarily conserved components of innate immunity characterized by their broad-spectrum efficacy and minimal resistance development, are increasingly recognized as promising therapeutic ...
Lala Stepanyan, Monika Israyelyan, Alessandro Gori, Avetis Tsaturyan, Zhaklina Saribekyan, Kristina Hovsepyan, Tatevik Sargsyan, Raffaele Pastore, Antonio De Luca, Giovanni N. Roviello   +9 more
doaj   +1 more source

Chicken Cathelicidins: Tissue Expression, Developmental Regulation, and Mass Spectrometric Quantification [PDF]

, 2010
The purposes of the study are to determine the tissue and developmental expressions of chicken cathelicidins and to develop a mass spectrometric assay for quantification of chicken cathelicidins.
Achanta, Mallika
core