Results 81 to 90 of about 6,173 (199)

SLURP2 Enlarges Adipocytes and Induces IL‐23‐Producing Macrophages in Murine Dermal Adipose Tissue

Experimental Dermatology, Volume 35, Issue 7, July 2026.
ABSTRACT Dermal adipocytes have unique features different from visceral and subcutaneous adipocytes. Their cyclic remodelling is coupled with hair follicle (HF) cycling: expansion in the anagen and reduction in the catagen stages. Secreted Ly6/uPAR related protein 2 (SLURP2) is a non‐neuronal transmitter and a ligand of both nicotinic and muscarinic ...
Hitomi Tsuji, Tomotaka Mabuchi
wiley   +1 more source

Efficacy and Safety of Supramolecular Salicylic Acid Combined With Intense Pulsed Light for Rosacea: A Split‐Face Trial

Journal of Cosmetic Dermatology, Volume 25, Issue 7, July 2026.
ABSTRACT Background Rosacea is a chronic inflammatory skin disorder with a global prevalence of approximately 5.46%, significantly impairing patients' quality of life and mental health. We aimed to assess the efficacy and safety of supramolecular salicylic acid (SSA) peeling combined with intense pulsed light (IPL) for rosacea and its impact on skin ...
Meifang Wang, Ansheng Tan, Fenglin Zhuo
wiley   +1 more source

Cathelicidins inhibit Escherichia coli-induced TLR2 and TLR4 activation in a viability-dependent manner [PDF]

, 2017
Activation of the immune system needs to be tightly regulated to provide protection against infections and, at the same time, to prevent excessive inflammation to limit collateral damage to the host.
Albert van Dijk, Dep Infectieziekten Immunologie, dI&I I&I-3, dI&I RA-I&I I&I, de Groot, A Marit, Haagsman, Henk P., Coorens, Maarten, Henk P. Haagsman, Groot, A.M., De, Scheenstra, Maaike R., Viktoria A. F. Schneider, van Dijk, Albert, Wells, Jerry M, Schneider, Viktoria A.F., Veldhuizen, Edwin J A, Veldhuizen, Edwin J.A., Maaike R. Scheenstra, Scheenstra, Maaike R, Van Dijk, Albert I.J.M., De Groot, A.M., Schneider, Viktoria A F, Marjolein Meijerink, Haagsman, Henk P, Dijk, Albert I.J.M., Van, Infection & Immunity, A. Marit de Groot, Edwin J. A. Veldhuizen, Wells, Jerry M., Jerry M. Wells, Maarten Coorens, Meijerink, Marjolein   +30 more
core   +1 more source

Vitamin D receptor signaling in inflammatory senescence–associated skin aging: Mechanisms and therapeutic potentials

Journal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
Vitamin D receptor (VDR) signaling is implicated in inflammatory senescence‐associated skin aging, a growing health concern in aging populations where cellular senescence and chronic inflammation converge to create complex pathophysiological conditions.
Liancheng Guan, Fan Yang, Meijuan Li, Yujia Chen, Zexin Zhao, Hongxia Li, Deping Luo, Qian Li, Yunzhi Chen   +8 more
wiley   +1 more source

Peptide RL‐QN15 Regulates Functions of Epidermal Stem Cells to Accelerate Skin Wound Regeneration via the FZD8/β‐Catenin Axis

Exploration, Volume 6, Issue 3, June 2026.
Amphibian‐derived peptide RL‐QN15 activates the Wnt/β‐catenin signaling pathway by interacting with the FZD8 membrane receptor, promoting epidermal stem cells proliferation, migration, stemness, and EMT processes, thus promoting skin wound healing.
Yuansheng Li, Qiuye Jia, Naixin Liu, Saige Yin, Junyuan Wang, Yujing Ding, Yuliu Yang, Ying Peng, Zeqiong Ru, Shaoyang Zhang, Bu'er Qi, Jun Sun, Li He, Ying Wang, Kun Guo, Xinwang Yang   +15 more
wiley   +1 more source

Uncovering the Function of Marsupial Cathelicidins: Macrophage Modulation and Direct Antibacterial Defense

, 2023
To counter bacterial threats immediately after birth, marsupial neonates rely on powerful innate immunity factors, as they are incapable of mounting an adaptive immune response.
Kaage, Aellah
core  

Image_1_Expression Pattern of Cathelicidins in Dairy Cows During Endometritis and Role of Bovine Endometrial Epithelial Cells in Production of Cathelicidins.PNG

, 2021
Endometritis is a common bacterial disease of dairy cows. Cathelicidins are host-defense peptides that play important roles in clearance of bacteria. However, the expression pattern of these peptides during endometritis is still unclear.
Xiaoyu Ma (831683), Xiaohu Wu (1940080), Yajuan Li (402995), Zuoting Yan (10891521), Baoxiang He (11454025), Jie Yang (121778)   +5 more
core   +1 more source

Role of Cathelicidins in Atherosclerosis and Associated Cardiovascular Diseases

Journal of Molecular Pathology
Cathelicidins (human LL-37 and rat CRAMP) are multifunctional peptides involved in various cardiovascular conditions. This review integrates the recent findings about the functional involvement of LL-37/CRAMP across atherosclerosis, acute coronary ...
Siarhei A. Dabravolski, Nikolay A. Orekhov, Alexey V. Churov, Irina A. Starodubtseva, Dmitry F. Beloyartsev, Tatiana I. Kovyanova, Vasily N. Sukhorukov, Alexander N. Orekhov   +7 more
doaj   +1 more source

Engineered Bacillus subtilis regulates intestinal barrier in ETEC K88‐infected piglets and modulates miR‐1250‐5p/NFκB pathway in IPEC‐J2

iMetaOmics, Volume 3, Issue 2, June 2026.
Upon enterotoxigenic Escherichia coli (ETEC) K88 infection, intestinal barrier function is disrupted with compromised tight junctions, accompanied by an exacerbated inflammatory response, proliferation of pathogenic Escherichia, and depletion of beneficial Lactobacillus paralimentarius.
Chaoyue Wen, Hong Zhang, Qiuping Guo, Yehui Duan, Sisi Chen, Mengmeng Han, Leli Wang, Le Huang, Yuankun Deng, Fengna Li, Yizhen Wang, Mingliang Jin   +11 more
wiley   +1 more source

Cathelicidin Insufficiency in Patients with Fatal Leptospirosis

PLOS Pathogens, 2016
Leptospirosis causes significant morbidity and mortality worldwide; however, the role of the host immune response in disease progression and high case fatality (>10-50%) is poorly understood. We conducted a multi-parameter investigation of patients with acute leptospirosis to identify mechanisms associated with case fatality.
Janet C. Lindow, Elsio A. Wunder, Stephen J. Popper, Jin-na Min, Praveen Mannam, Anup Srivastava, Yi Yao, Kathryn P. Hacker, Khadir Raddassi, Patty J. Lee, Ruth R. Montgomery, Albert C. Shaw, Jose E. Hagan, Guilherme C. Araújo, Nivison Nery, David A. Relman, Charles C. Kim, Mitermayer G. Reis, Albert I. Ko   +18 more
openaire   +4 more sources