Results 101 to 110 of about 6,173 (199)

Cathelicidin host defence peptide augments clearance of pulmonary Pseudomonas aeruginosa infection by its influence on neutrophil function in vivo.

PLoS ONE, 2014
Cathelicidins are multifunctional cationic host-defence peptides (CHDP; also known as antimicrobial peptides) and an important component of innate host defence against infection.
Paula E Beaumont, Brian McHugh, Emily Gwyer Findlay, Annie Mackellar, Karen J Mackenzie, Richard L Gallo, John R W Govan, A John Simpson, Donald J Davidson   +8 more
doaj   +1 more source

Porcine cathelicidins efficiently complex and deliver nucleic acids to plasmacytoid dendritic cells and can thereby mediate bacteria-induced IFN-α responses.

, 2014
Cathelicidins constitute potent antimicrobial peptides characterized by a high cationic charge that enables strong interactions with nucleic acids.
Python, Sylvie, Demoulins, Thomas, Summerfield, Artur, Baumann, Arnaud   +3 more
core   +1 more source

ANTIMICROBIAL PEPTIDES — A POTENTIAL REPLACEMENT FOR TRADITIONAL ANTIBIOTICS

Инфекция и иммунитет, 2018
Antimicrobial peptides are a heterogeneous group of molecules involved in the innate and acquired immune response of various organisms, ranging from prokaryotes to mammals, including humans.
Kh. G. Musin
doaj   +1 more source

Peptides from the Pouch: Marsupial and Monotreme Cathelicidins

, 2018
The rise in antimicrobial resistance and paucity of new antimicrobial compounds calls for alternatives to traditional antibiotics. Antimicrobial peptides (AMPs) have emerged as potential candidates.
Peel, Emma Jane
core  

Recent advances in the field of antimicrobial peptides in inflammatory diseases

Advanced Biomedical Research, 2013
Antimicrobial peptides are cationic molecules, which participate in multiple aspects of the immune response including the control of inflammatory diseases, characteristic that make these molecules attractive as therapeutic tools.
Patricia Méndez-Samperio
doaj   +1 more source

Characterization of the salmonid cathelicidins and of their biological activities

, 2013
Two cathelicidins have been identified in salmonids and other fish. We characterized the antimicrobial activity spectrum , mode of action and tissue expression of salmon cathelicidins.
VENIER, PAOLA, G. Cannone, M. Furlan, A. Pallavicini, M. Scocchi, ROSANI, UMBERTO, IRATO, PAOLA   +6 more
core  

Purification and structural characterization of bovine cathelicidins, precursors of antimicrobial peptides

, 1996
Cathelicidins are a novel family of antimicrobial peptide precursors from mammalian myeloid cells. They are characterized by a conserved N-terminal region while the C-terminal antimicrobial domain can vary considerably in both primary sequence and length.
Brigita Lenarcic, TOSSI, ALESSANDRO, Alessandro Tossi, Domenico Romeo, P. STORICI, B. LENARCIC, ROMEO, DOMENICO, Paola Storici   +7 more
core   +1 more source

Antimicrobial peptides and other potential biomarkers of critical illness in SARS‐CoV‐2 patients with acute kidney injury. AMPAKI‐CoV study

Physiological Reports
Antimicrobial peptides (AMPs) constitute a complex network of 10–100 amino acid sequence molecules widely distributed in nature. While over 300 AMPs have been described in mammals, cathelicidins and defensins remain the most extensively studied.
Lucas Ferreira Theotonio dos Santos, Hermes Vieira Barbeiro, Denise Frediani Barbeiro, Heraldo Possolo deSouza, Fabiano Pinheiro da Silva   +4 more
doaj   +1 more source

Chicken Cathelicidins: Tissue Expression, Developmental Regulation, and Mass Spectrometric Quantification

, 2010
The purposes of the study are to determine the tissue and developmental expressions of chicken cathelicidins and to develop a mass spectrometric assay for quantification of chicken cathelicidins.
Achanta, Mallika
core   +1 more source

Fungicidal mechanisms of cathelicidins LL-37 and CATH-2 revealed by live-cell imaging

, 2014
Antifungal mechanisms of action of two cathelicidins, chicken CATH-2 and human LL-37, were studied and compared with the mode of action of the salivary peptide histatin 5 (Hst5).
Biology of Reproductive Cells, Wubbolts, Richard W, LS Celbiologie-Algemeen, Strategic Infection Biology, Sub Center for Cell Imaging, I&I SIB3, Ordonez Alvarez, Soledad, Veldhuizen, Edwin J A, LS Moleculaire Afweer, Haagsman, Henk P, Amarullah, Ilham H, B&C BRC-SIB   +11 more
core   +1 more source