Results 51 to 60 of about 3,232 (162)
Hidradenitis suppurativa skin microbiome: In‐depth analysis and modulation by systemic therapies
Journal of the European Academy of Dermatology and Venereology, EarlyView.Hidradenitis suppurativa skin exhibits profound dysbiosis, characterized by the depletion of homeostatic commensals and expansion of anaerobic pathogens. Longitudinal evaluation reveals that while systemic antibiotics successfully reverse HS dysbiosis, biologics (adalimumab and secukinumab) fail to clear pathogens despite clinical healing.
Yacine Amar +8 more
wiley +1 more source
Cathelicidins: an ancient family of fish antimicrobial peptides
, 2016 Cathelicidins are an important family of antimicrobial peptide effectors of innate immunity in vertebrates. While their mammalian counterparts have been extensively characterized in the last two decades, data on fish cathelicidins has only recently been ...
Alberto Pallavicini +7 more
core +1 more source
Inflammatory and Immunological Basis of Periodontal Diseases
Journal of Periodontal Research, EarlyView.The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima +3 more
wiley +1 more source
DataSheet_1_Snake Venom Cathelicidins as Natural Antimicrobial Peptides.pdf
, 2019 Bioactive small molecules isolated from animals, plants, fungi and bacteria, including natural antimicrobial peptides, have shown great therapeutic potential worldwide.
Elizângela de Barros (8058836) +5 more
core +1 more source
mBio, 2019 All metazoans produce antimicrobial peptides (AMPs) that have both broad antimicrobial and immunomodulatory activity. Cathelicidins are AMPs that preferentially kill Gram-negative bacteria in vitro, purportedly by assembling into higher-order structures ...
Dean A. Rowe-Magnus +4 more
doaj +1 more source
Autoimmunity and Periodontitis
Journal of Periodontal Research, EarlyView.In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga +2 more
wiley +1 more source
Frontiers in Microbiology, 2018 Digital dermatitis (DD) commonly associated with Treponema spp. infection is a prevalent infectious bovine foot disease characterized by ulcerative and necrotic lesions.
Kaitlyn M. Watts +9 more
doaj +1 more source
Maternal Dietary Inflammatory Index and Biomarkers of Inflammation at Birth
Maternal &Child Nutrition, EarlyView.ABSTRACT We evaluated the association between the inflammatory potential of the maternal diet during pregnancy and levels of inflammatory biomarkers measured in cord blood and maternal serum at birth. Dietary inflammatory potential was calculated using the energy‐adjusted dietary inflammatory index (E‐DII) in the French EDEN and ELFE birth cohorts ...
Courtney Dow +9 more
wiley +1 more source
, 2023 To counter bacterial threats immediately after birth, marsupial neonates rely on powerful innate immunity factors, as they are incapable of mounting an adaptive immune response.
Kaage, Aellah
core
Induction of clnR is specific to LL-37-like cathelicidins.
, 2018 Induction of clnR is specific to LL-37-like cathelicidins.
Adrianne N. Edwards (5646344) +4 more
core +1 more source