Results 11 to 20 of about 144,512 (348)

Systems analysis of host–parasite interactions [PDF]

open access: hybridWIREs Systems Biology and Medicine, 2015
Parasitic diseases caused by protozoan pathogens lead to hundreds of thousands of deaths per year in addition to substantial suffering and socioeconomic decline for millions of people worldwide. The lack of effective vaccines coupled with the widespread emergence of drug‐resistant parasites necessitates that the research community take an active role ...
Justine Swann   +3 more
core   +9 more sources

Cryptosporidium: Host-Parasite Interactions and Pathogenesis. [PDF]

open access: yesCurr Clin Microbiol Rep, 2021
Cryptosporidium spp. (C. hominis and C. parvum) are a major cause of diarrhea-associated morbidity and mortality in young children globally. While C. hominis only infects humans, C. parvum is a zoonotic parasite that can be transmitted from infected animals to humans.
Pinto DJ, Vinayak S.
europepmc   +5 more sources

Transcriptional patterns of sexual dimorphism and in host developmental programs in the model parasitic nematode Heligmosomoides bakeri

open access: yesParasites & Vectors, 2023
Background Heligmosomoides bakeri (often mistaken for Heligmosomoides polygyrus) is a promising model for parasitic nematodes with the key advantage of being amenable to study and manipulation within a controlled laboratory environment.
Stephen M. J. Pollo   +5 more
doaj   +1 more source

Seasonal epidemiology of gastrointestinal nematodes of cattle in the northern continental climate zone of western Canada as revealed by internal transcribed spacer-2 ribosomal DNA nemabiome barcoding

open access: yesParasites & Vectors, 2021
Background Gastrointestinal nematode (GIN) epidemiology is changing in many regions of the world due to factors such as global warming and emerging anthelmintic resistance.
Tong Wang   +10 more
doaj   +1 more source

An Improved Method to Enrich Large Extracellular Vesicles Derived from Giardia intestinalis through Differential Centrifugation

open access: yesLife, 2023
Giardia intestinalis is a flagellated unicellular protozoan that colonizes the small intestine, causing the diarrheal disease called giardiasis. The production of extracellular vesicles (EVs) by G. intestinalis and the role of these EVs in the parasite’s
Abel Sana   +5 more
doaj   +1 more source

Chlamydia trachomatis suppresses host cell store-operated Ca2+ entry and inhibits NFAT/calcineurin signaling

open access: yesScientific Reports, 2022
The obligate intracellular bacterium, Chlamydia trachomatis, replicates within a parasitophorous vacuole termed an inclusion. During development, host proteins critical for regulating intracellular calcium (Ca2+) homeostasis interact with the inclusion ...
Nicholas B. Chamberlain   +2 more
doaj   +1 more source

Trickle infection with Heligmosomoides polygyrus results in decreased worm burdens but increased intestinal inflammation and scarring

open access: yesFrontiers in Immunology, 2022
IntroductionIntestinal roundworms cause chronic debilitating disease in animals, including humans. Traditional experimental models of these types of infection use a large single-dose infection. However, in natural settings, hosts are exposed to parasites
Anupama Ariyaratne   +23 more
doaj   +1 more source

Performance of a universal PCR assay to identify different Leishmania species causative of Old World cutaneous leishmaniasis

open access: yesParasites & Vectors, 2020
Background The characterization of Leishmania species is important for clinical management of the diseases and the epidemiological control of the parasite distribution.
Mahmoud Nateghi Rostami   +4 more
doaj   +1 more source

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