Results 21 to 30 of about 153,349 (341)

Benefits of host genetic diversity for resistance to infection depend on parasite diversity [PDF]

, 2010
Host populations with high genetic diversity are predicted to have lower levels of infection prevalence. This theory assumes that host genetic diversity results in variation in susceptibility and that parasites exhibit variation in infectivity. Empirical
Ebert, D., Ganz, H.
core   +1 more source

Isothermal diagnostic assays for the detection of soil-transmitted helminths based on the SmartAmp2 method

Parasites & Vectors, 2017
Background Diagnosis of soil-transmitted helminths (STHs) has traditionally relied on stool microscopy, which has a number of critical deficiencies. Molecular diagnostics are powerful tools to identify closely related species, but the requirement for ...
Nour Rashwan, Aïssatou Diawara, Marilyn E. Scott, Roger K. Prichard   +3 more
doaj   +1 more source

Perspectives on the Trypanosoma cruzi-host cell receptor interaction [PDF]

, 2009
Chagas disease is caused by the parasite Trypanosoma cruzi. The critical initial event is the interaction of the trypomastigote form of the parasite with host receptors. This review highlights recent observations concerning these interactions.
A Belley, A Buschiazzo, AC Frasch, AC Monteiro, AC Monteiro, AG Todorov, AJS Augustine, AK Vaidian, AL Leal, AM Celentano, AM Silber, AM Woolsey, Anthony W. Ashton, AP Lima, AW Ashton, AW Ashton, BA Burleigh, BA Burleigh, BA Burleigh, BK Kubata, C Claser, CA Buscaglia, CA Petersen, CW Turner, E Del Nery, E Ortega-Barria, F Leeb-Lundberg, F Marceau, F Villalta, F Villalta, F Villalta, F Villalta, F Villalta, F Villalta, F Villalta, F Villalta, F Villalta, F Villalta, Fabiana S. Machado, Fangxia Guan, Fernando Villalta, GS Hassan, HB Tanowitz, HB Tanowitz, HB Tanowitz, HB Tanowitz, Herbert B. Tanowitz, Huan Huang, IC Cuevas, IM Bastos, J Aliberti, J Scharfstein, J Scharfstein, JC Engel, JL Croxford, JM Di Noia, Julio Scharfstein, K Kabashima, KD Bhoola, Kevin M. Tyler, KJ Simmons, KM Tyler, L Sterin-Borda, LO Andrade, Louis M. Weiss, LX Liu, M de Melo-Jorge, M Einicker-Lamas, M Ming, MA Campos, MA Ouaissi, Maria F. Lima, MC Taylor, ME McGrath, MF Lima, MF Lima, MH Magdesian, MJ Alves, MN Meirelles, MV Chuenkova, MV Chuenkova, MV Chuenkova, MV Chuenkova, N Garg, N Garg, N Yoshida, P Grellier, PJ Pereira, PN Nde, R Agusti, R Giordano, R Manning-Cela, RA Skidgel, RL Cardoni, S Favoreto Jr, S Mukherjee, S Mukherjee, S Mukherjee, S Schenkman, S Vaena de Avalos, Sandra Alvarez, SB Petkova, SB Petkova, SG Andrade, Shankar Mukherjee, SM Factor, T Moody, VL Hideko Tatakihara, YY Kleshchenko   +108 more
core   +1 more source

HIF-1α hampers dendritic cell function and Th1 generation during chronic visceral leishmaniasis

Scientific Reports, 2018
Inflammation, although responsible for controlling infection, is often associated with the pathogenesis of chronic diseases. Leishmania donovani, the causative agent of visceral leishmaniasis, induces a strong inflammatory response that leads to ...
Akil Hammami, Belma Melda Abidin, Krista M. Heinonen, Simona Stäger   +3 more
doaj   +1 more source

Exploring the virulence gene interactome with CRISPR/dCas9 in the human malaria parasite

Molecular Systems Biology, 2020
Mutually exclusive expression of the var multigene family is key to immune evasion and pathogenesis in Plasmodium falciparum, but few factors have been shown to play a direct role.
Jessica M Bryant, Sebastian Baumgarten, Florent Dingli, Damarys Loew, Ameya Sinha, Aurélie Claës, Peter R Preiser, Peter C Dedon, Artur Scherf   +8 more
doaj   +1 more source

Chromatin structure can introduce systematic biases in genome-wide analyses of Plasmodium falciparum [version 2; peer review: 2 approved]

Open Research Europe, 2022
Background: The maintenance, regulation, and dynamics of heterochromatin in the human malaria parasite, Plasmodium falciparum, has drawn increasing attention due to its regulatory role in mutually exclusive virulence gene expression and the silencing of ...
Jessica Bryant, Sebastian Baumgarten
doaj   +1 more source

Influence of cold on host-parasite interactions. [PDF]

, 1963
pt.
Arctic Aeromedical Laboratory (U.S.), University of Alaska, Fairbanks. Geophysical Institute., Viereck, Eleanor.   +2 more
core   +2 more sources

What makes a host profitable? Parasites balance host nutritive resources against immunity [PDF]

, 2008
Numerous host qualities can modulate parasite fitness, and among these, host nutritive resources and immunity are of prime importance. Indeed, parasite fitness increases with the amount of nutritive resources extracted from the host body and decreases ...
Bize, P., Jeanneret, C., Klopfenstein, A., Roulin, A.   +3 more
core   +1 more source

Multiple drug resistance in hookworms infecting greyhound dogs in the USA

International Journal for Parasitology: Drugs and Drug Resistance, 2021
Ancylostoma caninum is the most prevalent nematode parasite of dogs. We confirmed multiple-drug resistance (MDR) in several A. caninum isolates to all anthelmintic drug classes approved for the treatment of hookworms in dogs in the USA.
Pablo D. Jimenez Castro, Abhinaya Venkatesan, Elizabeth Redman, Rebecca Chen, Abigail Malatesta, Hannah Huff, Daniel A. Zuluaga Salazar, Russell Avramenko, John S. Gilleard, Ray M. Kaplan   +9 more
doaj   +1 more source

Diverse Requirements for Src-Family Tyrosine Kinases Distinguish Chlamydial Species

mBio, 2011
Chlamydiae are well known for their species specificity and tissue tropism, and yet the individual species and strains show remarkable genomic synteny and share an intracellular developmental cycle unique in the microbial world.
Jeffrey Mital, Ted Hackstadt
doaj   +1 more source