Results 201 to 210 of about 227,089 (238)

The Impact of Obesity on the Host-Pathogen Interaction with Influenza Viruses - Novel Insights: Narrative Review. [PDF]

Diabetes Metab Syndr Obes
Miron VD, Drăgănescu AC, Pițigoi D, Aramă V, Streinu-Cercel A, Săndulescu O.   +5 more
europepmc   +1 more source

Inference of host-pathogen interaction matrices from genome-wide polymorphism data

, 2023
Märkle H, John S, Metzger L, STOP-HCV Consortium, Azim Ansari M, Pedergnana V, Tellier A.   +6 more
europepmc   +1 more source

The Transcription Factor FgSge1 Harnesses the SAGA Complex to Activate Mycotoxin Biosynthesis and Fungal Virulence

Advanced Science, EarlyView.
This study reveals the molecular mechanism by which the transcription factor FgSge1 regulates mycotoxin biosynthesis and virulence in Fusarium graminearum. FgSge1 binds to the TAARGTTT cis‐element, enabling self‐activation. It recruits the SAGA complex, promotes histone acetylation, and facilitates jet‐like chromatin remodeling, thereby activating ...
Yueqi Zhang, Jingrui Wang, Qiaowan Chen, Chen Jiao, Yun Chen, Zhongshou Wu, Zhonghua Ma   +6 more
wiley   +1 more source

Changes in primary metabolism and associated gene expression during host-pathogen interaction in clubroot resistance of Brassica napus. [PDF]

PLoS One
Ferdausi A, Megha S, Kav NNV, Rahman H.
europepmc   +1 more source

Bifidobacterium Breve Yang08 Alleviates Atopic Dermatitis By Enriching Akkermansia Muciniphila and Inhibiting Neutrophil Extracellular Traps Formation In Mice

Advanced Science, EarlyView.
A novel Bifidobacterium breve strain, Yang08, is isolated to counter its depletion in atopic dermatitis. In mice, live Yang08 requires an intact gut microbiota to exert protection, specifically enriching Akkermansia muciniphila and potently inhibiting pathogenic neutrophil activation and NETosis in the skin.
Yanqiang Shi, Shuang He, Chengyi Li, Hung Chan, Zhenfeng Liu, Bin Yang, Qing Li   +6 more
wiley   +1 more source

Chemosensory protein 16 has an immune function and participates in host-pathogen interaction in <i>Galleria mellonella</i> infected with <i>Pseudomonas entomophila</i>. [PDF]

Virulence
Kordaczuk J, Sułek M, Mak P, Frączek A, Wojda I.   +4 more
europepmc   +1 more source

Adipocyte‐Derived Exosomal miR‐5099 Mitigates M1 Macrophage Polarization and Adipose Inflammation via c‐Met/NF‐κB Axis to Improve Metabolic Health

Advanced Science, EarlyView.
Celastrol upregulates adipocyte‐derived exosomal miR‐5099, suppressing the macrophage c‐Met/NF‐κB axis to mitigate pro‐inflammatory M1 polarization and adipose inflammation. These miR‐5099‐enriched exosomes also act as endocrine signals targeting the liver, muscle, and adipocytes to significantly enhance systemic insulin sensitivity.
Ping Tang, Lixin Tai, Hongxia Xu, Dongliang Zhu, Jiajia Li, Hao Feng, Jinghui Cui, Shuhai Lin, Li‐jun Di, Li Wang   +9 more
wiley   +1 more source

Editorial: Legionella pneumophila-transmission, pathogenesis, host-pathogen interaction, prevention and treatment. [PDF]

Front Microbiol
Palusińska-Szysz M, Simões M.
europepmc   +1 more source

PAF Triggered Pyroptotic NETosis Aggravates Myocardial Ischemia/Reperfusion Injury

Advanced Science, EarlyView.
Platelet activating factor (PAF) secreted by cardiomyocytes during MI/R, drives NETs formation and subsequent NETosis. PAF/NETosis signaling activation is an initiative and causal factor in driving MI/R injury. This study identifies dapagliflozin as a potent NETosis inhibitor, and demonstrates that manipulating PAF‐NETosis signal by dapagliflozin or ...
Jiawei Wu, Shule Zhang, Ruofan Du, Lina Kang, Guodong Zhao, Xue Bao, Haochi Yang, Ziqing Xie, Tianyu He, Huiyong Sun, Haiping Hao, Lijuan Cao   +11 more
wiley   +1 more source

An Enzyme‐Like Catalyzed Nanosheets for Redox Stress Oscillation Therapy Against Bacterial Infections

Advanced Science, EarlyView.
Bacterial biofilms form a physicochemical barrier. Their dense network structure and redox homeostasis confer high resistance to antimicrobial treatments and immune‐mediated killing and clearance. In this study, SnSe nanosheets with enzyme‐like properties and piezoelectric catalysis can oscillate to regulate bacterial redox homeostasis and improve the ...
Min Ge, Zhao Guo, Zhiming Zhang, Lanlu Lu, Zesong Ruan, Tingwang Shi, Yunfeng Chen, Ju Huang, Chaoliang Tan, Han Lin   +9 more
wiley   +1 more source