Results 211 to 220 of about 227,089 (238)

Integrative Approaches to Treating Cellular Senescence in Kidney Disease

Advanced Science, EarlyView.
ABSTRACT Cellular senescence in the kidney plays a crucial role in the progression of acute kidney injury and chronic kidney disease. Therapeutic approaches targeting senescent cells, such as small molecule senolytic and senomorphic drugs, display efficacy in preclinical models.
Tomoka Misawa, Amruta A, LaTonya J. Hickson, Joy Wolfram   +3 more
wiley   +1 more source

Transcriptome analysis of Bipolaris sorokiniana - Hordeum vulgare provides insights into mechanisms of host-pathogen interaction. [PDF]

Front Microbiol
Basak P, Gurjar MS, Kumar TPJ, Kashyap N, Singh D, Jha SK, Saharan MS.   +6 more
europepmc   +1 more source

Cross‐Platform Biosensing of Immune Receptors Using Peptide‐Functionalized Graphene

Advanced Science, EarlyView.
A peptide‐functionalized graphene biosensor enables sensitive and selective detection of living immune cells. Targeting Formyl‐Peptide Receptor 2 (FPR2), the assay is demonstrated on model cells and primary human neutrophils. The same assay is applied to two complementary platforms: graphene‐enhanced surface plasmon resonance for optical benchmarking ...
Ahmar Hasnain, Heiko Heilmann, Annabel Pohl, Celine Weber, Bernd Bufe, Alexey Tarasov   +5 more
wiley   +1 more source

Humanized and Charge‐Optimized CSPG4‐Specific CAR‐T Cells show Enhanced Efficacy against Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
CSPG4 is identified as a high‐value, stemness‐associated target in HPV‐negative HNSCC. By implementing rational biophysical engineering, a humanized and charge‐optimized CAR is developed to overcome tonic signaling‐induced exhaustion. This strategy induces a profound transcriptomic shift toward a rejuvenated, stem‐like memory state, significantly ...
Xiang Xu, Shizhen Qiu, Zhitong Wang, Dan Li, Min Chen, Yinying Chu, Guangfei Li, Yi Fang, Changjiang Li, Fang Shi, Peijie He, Haitao Wu, Haopeng Wang, Jian Chen   +13 more
wiley   +1 more source

Insights into host-pathogen interaction based on the comparison of genomes of leptospira interrogans isolated from dogs, humans, and a rodent in the same epidemiological context: A one health approach. [PDF]

Heliyon
Paz LN, de Moraes L, Santos LA, Hamond C, Pinna MH.   +4 more
europepmc   +1 more source

Dual RNA sequencing of Helicobacter pylori and host cell transcriptomes reveals ontologically distinct host-pathogen interaction. [PDF]

mSystems
Hu W, Zhai ZY, Huang ZY, Chen ZM, Zhou P, Li XX, Yang GH, Bao CJ, You LJ, Cui XB, Xia GL, Ou Yang MP, Zhang L, Wu WKK, Li LF, Zhang YX, Xiao ZG, Gong W.   +17 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Imaging host–pathogen interactions

Immunological Reviews, 2008
Summary: Imaging techniques have been revolutionized by advancements in both microscope instrumentation and data collection processing software. Immunologists and microbiologists now have access to a large panel of powerful technologies that are characterized by different spatial and time resolutions. In this review, we discuss recent studies in which
Laura, Campisi, Frédéric, Brau, Nicolas, Glaichenhaus   +2 more
openaire   +2 more sources

Host–Pathogen Interactions

2011
The outcome of an infection is determined by numerous interactions between hosts and pathogens occurring at many different biological levels, ranging from molecule to population. To develop new control strategies for infectious diseases in livestock species, appropriate methodologies are needed allowing more integrated system-level analysis in order to
Smits, M.A., Schokker, D.J.
openaire   +3 more sources

Host–pathogen interactions in sepsis

The Lancet Infectious Diseases, 2008
Sepsis is a major health problem. The concept that sepsis mortality is the result of an uncontrolled hyperinflammatory host response has recently been challenged. It is now widely thought that the host response to sepsis involves many, concomitant, integrated, and often antagonistic processes that involve both exaggerated inflammation and immune ...
Tom, van der Poll, Steven M, Opal
openaire   +2 more sources

Host–pathogen interactions

Current Opinion in Immunology, 2004
Tom H M, Ottenhoff, Michael J, Bevan
  +5 more sources