Results 271 to 280 of about 247,353 (310)
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Host–pathogen interactions in sepsis
The Lancet Infectious Diseases, 2008Sepsis is a major health problem. The concept that sepsis mortality is the result of an uncontrolled hyperinflammatory host response has recently been challenged. It is now widely thought that the host response to sepsis involves many, concomitant, integrated, and often antagonistic processes that involve both exaggerated inflammation and immune ...
Tom, van der Poll, Steven M, Opal
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Chikungunya virus: host pathogen interaction
Reviews in Medical Virology, 2011AbstractChikungunya is a re‐emerging arthropod‐borne viral disease caused by Chikungunya virus (CHIKV) belonging to the Togaviridae family of genus Alphavirus. It is a virus with a single stranded, positive sense RNA, as its genome. It is maintained in a sylvatic and urban cycle involving humans and the mosquito species Aedes aegypti and Aedes ...
Sunit Kumar, Singh +1 more
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Genomics of host–pathogen interactions
Current Opinion in Immunology, 2014The study of immunity against infection can be framed in the context of genomics. First, long-term association with pathogens results in genomic signatures that result from positive selection. Evolutionary pressures tailor species or individual responses to pathogens, that may be associated with skewed patterns of immunity.
Rausell Antonio, Telenti Amalio
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Candida morphogenesis and host–pathogen interactions
Current Opinion in Microbiology, 2004The human fungal pathogen Candida albicans has many morphological forms. Recent advances in genomics and cell biology are providing an improved understanding of the molecular regulation of cell shape, and providing insights into the relationships between morphogenesis and virulence.
Whiteway, Malcolm, Oberholzer, Ursula
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Growth and Host–Pathogen Interactions
2008Differing trajectories of infant and child growth are associated with different patterns of disease and mortality in adulthood. Since postnatal growth patterns are partially modifiable by diet, these associations raise fresh questions about what constitutes an optimal growth rate. We use data from contemporary societies that still suffer poor nutrition
Andrew M, Prentice, Momodou K, Darboe
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Genomics of host-pathogen interactions
2007The complete sequences of hundreds of microbial genomes have provided drug discovery pipelines with thousands of new potential drug targets. Their availability has also stimulated the development of a variety of innovative approaches that allow functional studies to be performed on the entire genome of an organism.
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Understanding host–pathogen interaction
Intensive Care Medicine, 2016K, Asehnoune +2 more
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