Prediction of motif-mediated viral mimicry through the integration of host-pathogen interactions. [PDF]
Idrees S, Paudel KR, Hansbro PM.
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ABSTRACT Background The pathogenesis of inflammation in eosinophilic chronic rhinosinusitis (ECRS) and non‐eosinophilic chronic rhinosinusitis (NECRS) remains poorly understood. This study aimed to assess immune cell infiltration within the sinonasal microenvironment in these conditions.
Katarzyna Czerwaty+5 more
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Modelling host-pathogen interactions: <i>Galleria mellonella</i> as a platform to study <i>Pseudomonas aeruginosa</i> response to host-imposed zinc starvation. [PDF]
Michetti E+5 more
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Alterations in gut microbiota and metabolites contribute to postoperative sleep disturbances
In this study, we classified postoperative patients into poor sleepers (PS) and good sleepers (GS) based on the bispectral index (BIS), and transplanted their fecal microbiota to pseudo‐germ‐free rats to analyze the sleep changes in rats and the potential mechanism.
Hui Zhong+7 more
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The intersection between host-pathogen interactions and metabolism during Vibrio cholerae infection. [PDF]
Dominguez SR, Doan PN, Rivera-Chávez F.
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Application of humanized mice in the safety experiments of antibody drugs
The graphical abstract of this review highlights the critical role of humanized mice in the safety evaluation of antibody drugs. First, the inherent immunogenicity of antibody drugs can lead to the production of antidrug antibodies and hypersensitivity reactions on repeated administration.
Zhimin Sun+9 more
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Modeling Host-Pathogen Interactions in C. elegans: Lessons Learned from Pseudomonas aeruginosa Infection. [PDF]
Hajdú G, Szathmári C, Sőti C.
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Sydenham's chorea (SC) is the neurological manifestation associated with acute rheumatic fever (ARF), triggered by a group A streptococcal (GAS) infection. Anti‐GAS antibodies cross‐reacting with tissue proteins are implicated in the development of neurological changes. In this study, using an animal model, we demonstrate that a compromised blood–brain
Rukshan Ahamed Mohamed Rafeek+8 more
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Timing matters in macrophage/CD4+ T cell interactions: an agent-based model comparing <i>Mycobacterium tuberculosis</i> host-pathogen interactions between latently infected and naïve individuals. [PDF]
Hoerter A+5 more
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