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Host–pathogen interactions in sepsis [PDF]
The Lancet Infectious Diseases, 2008 Sepsis is a major health problem. The concept that sepsis mortality is the result of an uncontrolled hyperinflammatory host response has recently been challenged. It is now widely thought that the host response to sepsis involves many, concomitant, integrated, and often antagonistic processes that involve both exaggerated inflammation and immune ...
Steven M. Opal, Tom van der Poll
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Imaging host–pathogen interactions
Immunological Reviews, 2008Summary: Imaging techniques have been revolutionized by advancements in both microscope instrumentation and data collection processing software. Immunologists and microbiologists now have access to a large panel of powerful technologies that are characterized by different spatial and time resolutions. In this review, we discuss recent studies in which
Nicolas Glaichenhaus +3 more
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Genomics of host–pathogen interactions
Current Opinion in Immunology, 2014The study of immunity against infection can be framed in the context of genomics. First, long-term association with pathogens results in genomic signatures that result from positive selection. Evolutionary pressures tailor species or individual responses to pathogens, that may be associated with skewed patterns of immunity.
Rausell Antonio, Telenti Amalio
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2011
The outcome of an infection is determined by numerous interactions between hosts and pathogens occurring at many different biological levels, ranging from molecule to population. To develop new control strategies for infectious diseases in livestock species, appropriate methodologies are needed allowing more integrated system-level analysis in order to
Smits, M.A., Schokker, D.J.
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The outcome of an infection is determined by numerous interactions between hosts and pathogens occurring at many different biological levels, ranging from molecule to population. To develop new control strategies for infectious diseases in livestock species, appropriate methodologies are needed allowing more integrated system-level analysis in order to
Smits, M.A., Schokker, D.J.
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Growth and Host–Pathogen Interactions
2008Differing trajectories of infant and child growth are associated with different patterns of disease and mortality in adulthood. Since postnatal growth patterns are partially modifiable by diet, these associations raise fresh questions about what constitutes an optimal growth rate. We use data from contemporary societies that still suffer poor nutrition
Momodou K. Darboe, Andrew M. Prentice
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Candida morphogenesis and host–pathogen interactions
Current Opinion in Microbiology, 2004The human fungal pathogen Candida albicans has many morphological forms. Recent advances in genomics and cell biology are providing an improved understanding of the molecular regulation of cell shape, and providing insights into the relationships between morphogenesis and virulence.
Whiteway, Malcolm, Oberholzer, Ursula
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Genomics of host-pathogen interactions
2007The complete sequences of hundreds of microbial genomes have provided drug discovery pipelines with thousands of new potential drug targets. Their availability has also stimulated the development of a variety of innovative approaches that allow functional studies to be performed on the entire genome of an organism.
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Veterinary Immunology and Immunopathology, 2004
Michael J. Bevan, Tom H. M. Ottenhoff
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Michael J. Bevan, Tom H. M. Ottenhoff
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