Results 91 to 100 of about 3,731,631 (387)

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

The endosymbiont Spiroplasma poulsonii increases Drosophila melanogaster resistance to pathogens by enhancing iron sequestration and melanization

mBio
Facultative endosymbiotic bacteria, such as Wolbachia and Spiroplasma species, are commonly found in association with insects and can dramatically alter their host physiology.
Alexandra Hrdina, Marina Serra Canales, Aranzazu Arias-Rojas, Dagmar Frahm, Igor Iatsenko   +4 more
doaj   +1 more source

Intertwined Dysregulation of Ribosomal Proteins and Immune Response Delineates SARS-CoV-2 Vaccination Breakthroughs

Microbiology Spectrum, 2023
Globally, COVID-19 vaccines have emerged as a boon, especially during the severe pandemic phases to control the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, saving millions of lives.
Ranjeet Maurya, Uzma Shamim, Pallavi Mishra, Aparna Swaminathan, Aakarshan Raina, Bansidhar Tarai, Sandeep Budhiraja, Rajesh Pandey   +7 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Genetic variability in the sdrD gene in Staphylococcus aureus from healthy nasal carriers

BMC Microbiology, 2018
Background Staphylococcus aureus cell wall anchored Serine Aspartate repeat containing protein D (SdrD) is a member of the microbial surface component recognising adhesive matrix molecules (MSCRAMMs).
Clement Ajayi, Espen Åberg, Fatemeh Askarian, Johanna U. E. Sollid, Mona Johannessen, Anne-Merethe Hanssen   +5 more
doaj   +1 more source

Scaling limits of a model for selection at two scales

, 2015
The dynamics of a population undergoing selection is a central topic in evolutionary biology. This question is particularly intriguing in the case where selective forces act in opposing directions at two population scales. For example, a fast-replicating
Luo, Shishi, Mattingly, Jonathan C.
core   +2 more sources

Odour-mediated orientation of beetles is influenced by age, sex and morph [PDF]

, 2012
The behaviour of insects is dictated by a combination of factors and may vary considerably between individuals, but small insects are often considered en masse and thus these differences can be overlooked.
A Salisbury, AJ Mossi, C Kestenholz, CW Fox, DA Ukeh, DT Nguyen, EA Elhag, ET Zannou, FJ Messina, FJ Messina, FJ Messina, FJ Messina, Frederic Marion-Poll, GH Caswell, HCF Su, HT Al-Lawati, I Sano-Fujii, I Sano-Fujii, J Hardie, J Jaba, J Kamanula, J Pickett, J Zhu, JC Dickens, JM van der Meer, JO Gendo, LK Miller, LPJJ Noldus, LR Hallsson, LR Hallsson, LS Nerio, MS Nahdy, P Lextrait, P Trematerra, PA Mackay, Philip C. Stevenson, RG Harrison, S Belmain, S Ignacimuthu, S Utida, S Williamson, SA Budick, Sarah E. J. Arnold, SJ Boeke, SJ Boeke, SJ Torr, Steven R. Belmain, T Bashir, TK Jayasekara, TK Jayasekara, Y-J Du   +50 more
core   +2 more sources

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Description of a new Crossidius LeConte (Coleoptera: Cerambycidae: Cerambycinae: Trachyderini) from southern Georgia with comments on its biology and unusual distribution [PDF]

, 2013
Crossidius grahami Morris and Wappes new species (Coleoptera: Cerambycidae) is described from the Ohoopee Dunes of southern Georgia. Comments are included on the new species’ biology and disjunct distribution compared to other species of Crossidius ...
Morris, Roy F., Wappes, James E.
core  

The SARS-coronavirus-host interactome [PDF]

, 2011
Coronaviruses (CoVs) are important human and animal pathogens that induce fatal respiratory, gastrointestinal and neurological disease. The outbreak of the severe acute respiratory syndrome (SARS) in 2002/2003 has demonstrated human vulnerability to ...
Brunn, Albrecht von, Carbajo-Lozoya, Javier, Dall'Armi, Ekatarina von, Ditt, Vanessa, Drosten, Christian, Friedel, Caroline C., Haas, Juergen G., Herrler, Georg, Herzog, Petra, Hilgenfeld, Rolf, Kallies, Stefan, Kuri, Thomas, Kögl, Manfred, Müller, Marcel A., Niemeyer, Daniela, Pfefferle, Susanne, Pumpor, Ksenia, Pöhlmann, Stefan, Schwarz, Frank, Schwegmann-Wessels, Christel, Schöpf, Julia, Steffen, Imke, Stellberger, Thorsten, Thiel, Heinz-Jürgen, Thiel, Volker, Weber, Friedemann, Zimmer, Ralf, Züst, Roland   +27 more
core   +1 more source