Results 241 to 250 of about 181,738 (289)

Proteome‐Wide Analysis of Palmitoylated Proteins in Macrophages Reveals Novel Insights Into Early Immune Signaling

PROTEOMICS, EarlyView.
ABSTRACT Protein S‐palmitoylation, a reversible lipid modification, plays critical roles in regulating protein function and localization. However, its comprehensive role in the rapid reprogramming of macrophages during early immune responses remains incompletely understood.
Hyojung Kim, Jiraphorn Issara‐Amphorn, Sung Hwan Yoon, Anirban Banerjee, Aleksandra Nita‐Lazar   +4 more
wiley   +1 more source

Demystifying fungal systematics: A gateway to fungal literacy and societal/ecological relevance through familiar species

PLANTS, PEOPLE, PLANET, EarlyView.
Fungal systematics can feel overwhelming given the vast species diversity within this kingdom, with numerous subgroups at every taxonomic rank. This often creates a disconnect between the undertsnidng of fungal taxonomic diversity and their societal relevance.
Anna Vaiana, Francis Martin, Rasmus Kjøller, Toby Spribille, Garima Singh   +4 more
wiley   +1 more source

Engineering nucleotide‐binding leucine‐rich repeat immune receptors to achieve broad‐spectrum disease resistance in plants

New Plant Protection, EarlyView.
Yan Wang, Yuzhen Mei, Fangfang Li
wiley   +1 more source

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Avian host defense peptides

Developmental & Comparative Immunology, 2013
Host defense peptides (HDPs) are important effector molecules of the innate immune system of vertebrates. These antimicrobial peptides are also present in invertebrates, plants and fungi. HDPs display broad-spectrum antimicrobial activities and fulfill an important role in the first line of defense of many organisms.
Cuperus, Tryntsje, Coorens, M., van Dijk, A., Haagsman, H.P.   +3 more
openaire   +4 more sources

Antimicrobial Peptides: Amphibian Host Defense Peptides

Current Medicinal Chemistry, 2019
Antimicrobial Peptides (AMPs) are one of the most common components of the innate immune system that protect multicellular organisms against microbial invasion. The vast majority of AMPs are isolated from the frog skin. Anuran (frogs and toads) skin contains abundant AMPs that can be developed therapeutically.
Jiri, Patocka, Eugenie, Nepovimova, Blanka, Klimova, Qinghua, Wu, Kamil, Kuca   +4 more
openaire   +2 more sources

Cationic host defense (antimicrobial) peptides

Current Opinion in Immunology, 2006
Members of the cationic host defense (antimicrobial) peptide family are widely distributed in nature, existing in organisms from insects to plants to mammals and non-mammalian vertebrates. Although many demonstrate direct antimicrobial activity against bacteria, fungi, eukaryotic parasites and/or viruses, it has been established that cationic peptides ...
Kelly L, Brown, Robert E W, Hancock
openaire   +2 more sources

Host defense peptides in burns

Burns, 2004
Overuse of antibiotics and failure to apply basic infection control policies and procedures have contributed to the increasing multi-drug resistance of many nosocomial pathogens. The alarming increase of multi-drug-resistant bacteria (e.g. Pseudomonas aeruginosa, methicilin-resistant Staphylococci, vancomycin-resistant Enterococci) causes infected ...
L, Steinstraesser, Y, Oezdogan, S C, Wang, H U, Steinau   +3 more
openaire   +2 more sources

Host defense peptides: front-line immunomodulators

Trends in Immunology, 2014
Although first studied for their antimicrobial activity, host defense peptides (HDPs) are now widely recognized for their multifunctional roles in both the innate and adaptive immune responses. Their diverse immunomodulatory capabilities include the modulation of pro- and anti-inflammatory responses, chemoattraction, enhancement of extracellular and ...
Sarah C, Mansour, Olga M, Pena, Robert E W, Hancock   +2 more
openaire   +2 more sources

Antiviral Activities of Human Host Defense Peptides

Current Medicinal Chemistry, 2020
Peptides with broad-spectrum antimicrobial activity are found widely expressed throughout nature. As they participate in a number of different aspects of innate immunity in mammals, they have been termed Host Defense Peptides (HDPs). Due to their common structural features, including an amphipathic structure and cationic charge, they have been widely ...
David C, Brice, Gill, Diamond
openaire   +2 more sources

Natural History of Innate Host Defense Peptides

Probiotics and Antimicrobial Proteins, 2009
Host defense peptides act on the forefront of innate immunity, thus playing a central role in the survival of animals and plants. Despite vast morphological changes in species through evolutionary history, all animals examined to date share common features in their innate immune defense strategies, hereunder expression of host defense peptides (HDPs ...
A, Linde, B, Wachter, O P, Höner, L, Dib, C, Ross, A R, Tamayo, F, Blecha, T, Melgarejo   +7 more
openaire   +2 more sources