Results 111 to 120 of about 9,445,813 (266)

The Interplay of Viral and Host Factors in Chikungunya Virus Infection: Targets for Antiviral Strategies

open access: yesViruses, 2018
Chikungunya virus (CHIKV) has re-emerged as one of the many medically important arboviruses that have spread rampantly across the world in the past decade.
Kai Zhi Wong, Justin Jang Hann Chu
doaj   +1 more source

Transcriptional profiling of zebrafish identifies host factors controlling susceptibility to Shigella flexneri [PDF]

open access: yes
Shigella flexneri is a human-adapted pathovar of Escherichia coli that can invade the intestinal epithelium, causing inflammation and bacillary dysentery. Although an important human pathogen, the host response to S. flexneri has not been fully described.
Mazon-Moya, M.   +7 more
core   +1 more source

Evolutionary and proximate mechanisms shaping host-parasite interactions : the case of "Daphnia magna" and its natural bacterial parasite "Pasteuria ramosa" [PDF]

open access: yes, 2011
Host-parasite interactions are composed of a sequence of steps, all necessary for successful infection: parasites need to encounter their hosts, to enter into their bodies, and to proliferate within them. Selection will act on the mechanisms used in each
Duneau, David
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Replication Cycle and Molecular Biology of the West Nile Virus

open access: yesViruses, 2013
West Nile virus (WNV) is a member of the genus Flavivirus in the family Flaviviridae. Flaviviruses replicate in the cytoplasm of infected cells and modify the host cell environment.
Margo A. Brinton
doaj   +1 more source

Cooperative secretions facilitate host range expansion in bacteria [PDF]

open access: yes, 2014
The majority of emergent human pathogens are zoonotic in origin, that is, they can transmit to humans from other animals. Understanding the factors underlying the evolution of pathogen host range is therefore of critical importance in protecting human ...
Viana, Mafalda   +3 more
core   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

A study to evaluate host factors for musculoskeletal injuries secondary to trauma among elderly people of Northwestern India

open access: yesJournal of the Scientific Society, 2016
Introduction: As the population ages, the problems related to falls and fractures are expected to grow. This poses a great challenge to the health-care systems. Meeting these challenges requires a clear understanding of the prevalence and nature of falls.
Sunil Kumar Raina   +3 more
doaj   +1 more source

Host-specific cues cause differential attractiveness of Kenyan men to the African malaria vector Anopheles gambiae [PDF]

open access: yes, 2002
Background Many studies have suggested that variability in the attractiveness of humans to host-seeking mosquitoes is caused by differences in the make-up of body emanations, and olfactory signals in particular.
Knols, B.G.J.   +11 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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