Results 41 to 50 of about 9,445,813 (266)

A Comprehensive View on the Host Factors and Viral Proteins Associated With Porcine Epidemic Diarrhea Virus Infection

Frontiers in Microbiology, 2021
Porcine epidemic diarrhea virus (PEDV), a coronavirus pathogen of the pig intestinal tract, can cause fatal watery diarrhea in piglets, thereby causing huge economic losses to swine industries around the world.
Yi Hu, Xiaohong Xie, Lingchen Yang, Aibing Wang, Aibing Wang   +4 more
doaj   +1 more source

Viral-Host Dependency Factors as Therapeutic Targets to Overcome Antiviral Drug-Resistance: A Focus on Innate Immune Modulation

Frontiers in Virology, 2022
The development of antiviral drugs, has provided enormous achievements in our recent history in the fight against viral infections. To date, most of the approved antiviral drugs target virus-encoded proteins to achieve direct antiviral activity ...
Roger Badia, Roger Badia, Edurne Garcia-Vidal, Edurne Garcia-Vidal, Ester Ballana, Ester Ballana   +5 more
doaj   +1 more source

High water availability increases the negative impact of a native hemiparasite on its non-native host [PDF]

, 2016
Environmental factors alter the impacts of parasitic plants on their hosts. However, there have been no controlled studies on how water availability modulates stem hemiparasites' effects on hosts.
Facelli, JM, Cirocco, R., Cirocco, RM, Facelli, J., Cirocco, Robert, Watling, Jennifer, Watling, J., Watling, JR, Facelli, José   +8 more
core   +2 more sources

REPercussions: how geminiviruses recruit host factors for replication

Frontiers in Microbiology, 2023
Circular single-stranded DNA viruses of the family Geminiviridae encode replication-associated protein (Rep), which is a multifunctional protein involved in virus DNA replication, transcription of virus genes, and suppression of host defense responses ...
Sara Shakir, Muhammad Mubin, Nazia Nahid, Saad Serfraz, Muhammad Amir Qureshi, Taek-Kyun Lee, Iram Liaqat, Sukchan Lee, Muhammad Shah Nawaz-ul-Rehman   +8 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Ectoparasites associated with the Bushveld gerbil (Gerbilliscus leucogaster) and the role of the host and habitat in shaping ectoparasite diversity and infestations

Parasitology, 2023
Rodents are known hosts for various ectoparasite taxa such as fleas, lice, ticks and mites. South Africa is recognized for its animal diversity, yet little is published about the parasite diversity associated with wild rodent species.
Amber T. Smith, Boris R. Krasnov, Ivan G. Horak, Eddie A. Ueckermann, Sonja Matthee   +4 more
doaj   +1 more source

A whole genome screen for HIV restriction factors [PDF]

, 2011
Background Upon cellular entry retroviruses must avoid innate restriction factors produced by the host cell. For human immunodeficiency virus (HIV) human restriction factors, APOBEC3 (apolipoprotein-B-mRNA-editing-enzyme), p21 and tetherin are well ...
Dittmar Matthias T, Borgdorff Viola, Matthias T Dittmar, Kelly M Cheney, Áine McKnight, Borgdorff, V, Liu, L, Beach, DH, Pade Corinna, Dreja, H, McKnight, A, Pade, C, Cheney, KM, Dreja Hanna, Nidia MM Oliveira, Bergin, A-MH, Bishop, CL, Bergin Ann-Marie H, Beach David H, Cheney Kelly M, Cleo L Bishop, Dittmar, MT, Bishop Cleo L, Liu Li, David H Beach, Hanna Dreja, Li Liu, Ann-Marie H Bergin, Oliveira, NMM, McKnight Áine, Oliveira Nidia MM, Viola Borgdorff, Corinna Pade   +32 more
core   +8 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Role of protein Post-translational modifications in enterovirus infection

Frontiers in Microbiology
Enteroviruses (EVs) are the main cause of a number of neurological diseases. Growing evidence has revealed that successful infection with enteroviruses is highly dependent on the host machinery, therefore, host proteins play a pivotal role in viral ...
Xiaohui Zhao, Yibo Hu, Jun Zhao, Yan Liu, Xueman Ma, Hongru Chen, Yonghua Xing   +6 more
doaj   +1 more source

Hepatitis B Virus Capsid: The Core in Productive Entry and Covalently Closed Circular DNA Formation

Viruses, 2023
Hepatitis B virus (HBV) relies on the core protein (HBc) to establish productive infection, as defined by the formation of the covalently closed circularized DNA (cccDNA), as well as to carry out almost every step of the lifecycle following cccDNA ...
Megan A. Mendenhall, Xupeng Hong, Jianming Hu   +2 more
doaj   +1 more source