Results 101 to 110 of about 674,293 (317)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Diet quality determines interspecific parasite interactions in host populations [PDF]

, 2014
The widespread occurrence of multiple infections and the often vast range of nutritional resources for their hosts allow that interspecific parasite interactions in natural host populations might be determined by host diet quality. Nevertheless, the role
Lange, B., Ebert, Dieter, Reuter, M., Reuter, Max, Decaestecker, Ellen, Decaestecker, E., Muylaert, Koenraad, Muylaert, K., Lange, Benjamin   +8 more
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

The first vanE-type vancomycin resistant Enterococcus faecalis isolates in Norway – phenotypic and molecular characteristics

Journal of Global Antimicrobial Resistance
: Objectives: We aimed to characterize the vanE cluster and its genetic support in the first Norwegian vanE-type isolates and assess genetic relatedness to other vanE isolates.
Mushtaq AL Rubaye, Jessin Janice, Jørgen Vildershøj Bjørnholt, Iren H. Löhr, Arnfinn Sundsfjord, Kristin Hegstad   +5 more
doaj   +1 more source

Involvement of cathepsin B in the plant disease resistance hypersensitive response

, 2007
A diverse range of plant proteases are implicated in pathogen perception and in subsequent signalling and execution of disease resistance. We demonstrate, using protease inhibitors and virus-induced gene silencing (VIGS), that the plant papain cysteine ...
Shaw, Jane, Hein, I., Christophe Lacomme, Kaffarnik, Florian, Hein, Ingo, Lopez, Eduardo C., Eduard Venter, Van Der Hoorn, Renier, Paul R. J. Birch, Pritchard, L., Borras-Hidalgo, Orlando, Hazel McLellan, Gilroy, Eleanor M., McLellan, H., Eleanor M. Gilroy, Hrubikova, Katarina, Birch, P., Orlando Borras-Hidalgo, Boevink, P., Eduardo C. López, Shaw, J., Maria Holeva, Jane Shaw, Loake, Gary J., Hrubikova, K., Katarina Hrubikova, Boevink, Petra C., Holeva, Maria, Venter, Eduard, Kaffarnik, F., McLellan, Hazel, Van der Hoorn, R., Venter, E., Lopez, E., Gary J. Loake, Hein, Ingo; id_orcid, Florian Kaffarnik, Renier Van Der Hoorn, Birch, Paul R. J.; id_orcid, Lacomme, Christophe, Loake, G., Borras-Hidalgo, O., Pritchard, Leighton, Lacomme, C., Ingo Hein, Birch, Paul R. J., Leighton Pritchard, Holeva, M., Gilroy, E., Petra C. Boevink   +49 more
core   +1 more source

Interactive effects of protein nutrition, genetic growth potential and heligmosomoides bakeri infection pressure on resilience and resistance in mice [PDF]

, 2011
The ability of animals to cope with an increasing parasite load, in terms of resilience and resistance, may be affected by both nutrient supply and demand.
Houdijk, Jos G M, Allen, J.E., JENNIFER C. COLTHERD, Bunger, L., Coltherd, JC, Babayan, SA, Allen, JE, JOS G. M. HOUDIJK, JUDITH E. ALLEN, SIMON A. BABAYAN, Babayan, S.A., Houdijk, JGM; id_orcid, Kyriazakis, I., Allen, Judith E, Coltherd, J.C., Houdijk, J.G.M., Coltherd, Jennifer C, Kyriazakis, Ilias, ILIAS KYRIAZAKIS, Babayan, Simon A, LUTZ BÜNGER, Bunger, L, Kyriazakis, I, Bünger, Lutz   +23 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Prevalence of Plasmodium falciparum parasites harbouring chloroquine-resistant but not artemisinin-resistant alleles in Busia County, Western Kenya

Malaria Journal
Background The recent emergence of Plasmodium falciparum parasites harbouring kelch 13 mutations associated with artemisinin partial resistance (ART-R) in sub-Saharan Africa is a major concern. Regular molecular epidemiological surveys are recommended to
Noah Machuki Onchieku, Nemrod Gesusu, Emmanuelle Caspar, Lewis Karani, Kelvin Thiong’o, Luna Kamau, Daniel Kiboi, Lucas Thiebaut, Laurence Ma, Francis Kimani, Damaris Matoke-Muhia, Didier Ménard   +11 more
doaj   +1 more source

Multiple avirulence paralogues in cereal powdery mildew fungi may contribute to parasite fitness and defeat of plant resistance

, 2006
Powdery mildews, obligate biotrophic fungal parasites on a wide range of important crops, can be controlled by plant resistance (R) genes, but these are rapidly overcome by parasite mutants evading recognition.
Porritt, Oliver, Jones, Jonathan D. G., Porritt, O, Sacristan, S, Ridout, CJ, Ridout, Christopher J., Brown, James K. M., Skamnioti, Pari, Skamnioti, Paraskevi, Sacristán Benayas, Soledad, Brown, JK, Jones, JD   +11 more
core   +1 more source

Plant sulphur nutrition influencing host-plant selection and performance of insect herbivores [PDF]

, 2003
In the past several years, sulphur (S) deficiencies in agricultural crops have been reported with increasing frequency and therefore more interest has been directed into plant nutrition and fertilisation with particular respect to this element.
Marazzi, Cristina
core   +1 more source