Results 81 to 90 of about 674,293 (317)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Modeling the impact of host resistance on structured tick population dynamics

Mathematics in Applied Sciences and Engineering, 2020
For a variety of tick species, the resistance, behavioural and immunological response of hosts has been reported in the biological literature but its impact on tick population dynamics has not been mathematically formulated and analyzed using dynamical ...
Mahnaz Alavinejad, Jemisa Sadiku, Jianhong Wu   +2 more
doaj   +1 more source

Host Plant Resistance to Insects in Vegetable Crops

Host plant resistance is an effective approach to manage insect pests in vegetable crops. This approach involves the use of plant traits that deter or reduce insect feeding and reproduction involving the mechanisms of antibiosis, antixenosis, and ...
Kumaraswamy, Sunil, Nasif, Saifullah Omar, Siddique, Abu Bakar, Chowdary, Rajesh, Chaitanya, Alamuru Krishna, Karuppannasamy, Ashok, Mohan, Muthugounder   +6 more
core   +1 more source

Seven challenges in modelling pathogen dynamics within-host and across scales [PDF]

, 2014
The population dynamics of infectious disease is a mature field in terms of theory and to some extent, application. However for microparasites, the theory and application of models of the dynamics within a single infected host is still an open field ...
Lloyd-Smith, James O., Pellis, Lorenzo; id_orcid, McLean, Angela R, Gog, Julia R, McLean, AR, Gog, Julia R., Julia R. Gog, Lorenzo Pellis, Angela R. McLean, Pellis, Lorenzo, Wood, James L. N., Wood, James LN, Arinaminpathy, N, Lloyd-Smith, JO, Wood, James L.N., Wood, JLN, Nimalan Arinaminpathy, James L.N. Wood, Arinaminpathy, Nimalan, Lloyd-Smith, James O, McLean, Angela R., Pellis, L, James O. Lloyd-Smith, Gog, JR   +23 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

World malaria report 2025: Growing biological threats, shrinking resources

Decoding Infection and Transmission
The World Malaria Report 2025 documents operational progress while exposing systemic vulnerabilities that could reverse two decades of gains. Several biological threats are converging in Sub-Saharan Africa: artemisinin partial resistance, parasites ...
Lucien Platon, Feng Lu, Didier Ménard
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Identification and Analysis of Potential Genes Regulated by an Alphasatellite (TYLCCNA) that Contribute to Host Resistance against Tomato Yellow Leaf Curl China Virus and Its Betasatellite (TYLCCNV/TYLCCNB) Infection in Nicotiana benthamiana

Viruses, 2019
Recently, begomovirus/betasatellite disease complexes were found to be associated with alphasatellites, and their presence modulated disease symptoms and/or viral DNA accumulation in infected plants.
Chaohu Luo, Zhan Qi Wang, Xianan Liu, Liling Zhao, Xueping Zhou, Yan Xie   +5 more
doaj   +1 more source

Host Resistance and The Immune System

Clinics in Geriatric Medicine, 1992
Elderly persons are more susceptible and vulnerable to many infections compared with young adults. This phenomenon can be attributed to a decline in host defense mechanisms, particularly altered immune function. The effects of aging on T- and B-lymphocyte function; antigen-presenting cells, natural killer cells, and granulocytes; and organ-specific ...
A, Ben-Yehuda, M E, Weksler
openaire   +2 more sources

Host resistance and the evolutionary response of plant viruses

, 2006
1. Plant virus diseases severely constrain agricultural production world-wide, especially in less developed countries. The use of resistant cultivars may put a selection pressure on the plant virus to evolve towards more aggressive types.
MIKE JEGER, SUE SEAL, FRANK VAN DEN BOSCH, GORDON AKUDIBILAH, Van Den Bosch, F., Akudibilah, G., Jeger, M., Seal, S.   +7 more
core   +1 more source