Results 91 to 100 of about 2,186,753 (294)

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

HostPhinder: A Phage Host Prediction Tool

Viruses, 2016
The current dramatic increase of antibiotic resistant bacteria has revitalised the interest in bacteriophages as alternative antibacterial treatment. Meanwhile, the development of bioinformatics methods for analysing genomic data places high-throughput ...
Julia Villarroel, Kortine Annina Kleinheinz, Vanessa Isabell Jurtz, Henrike Zschach, Ole Lund, Morten Nielsen, Mette Voldby Larsen   +6 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Correction: Corrigendum: Allelic variation contributes to bacterial host specificity

Nature Communications, 2017
Nature Communications 6 Article: 8754 (2015); Published: 30 Octomber 2015; Updated: 8 August 2017 In Fig. 3 of this Article, the numbers of isolates studied for the fimH41_Newp, fimH44_Newp and fimH45_Newp alleles were inadvertently swapped.
Min Yue, Xiangan Han, Leon De Masi, Chunhong Zhu, Xun Ma, Junjie Zhang, Renwei Wu, Robert Schmieder, Radhey S. Kaushik, George P. Fraser, Shaohua Zhao, Patrick F. McDermott, François-Xavier Weill, Jacques G. Mainil, Cesar Arze, W. Florian Fricke, Robert A. Edwards, Dustin Brisson, Nancy R. Zhang, Shelley C. Rankin, Dieter M. Schifferli   +20 more
doaj   +1 more source

Viral wheezing is virus specific and not just host specific [PDF]

European Respiratory Journal, 2011
To the Editors: In a recent issue of the European Respiratory Journal , Strippoli et al. [1] reported their interesting findings on exclusive viral wheezing versus allergic wheezing in a large population-based, prospectively followed cohort including 4,102 children at 1 yr and 1,858 children at 9 yrs of age. The parents reported current wheezing in 36,
openaire   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Temporospatial dynamics and host specificity of honeybee gut bacteria

Cell Reports
Summary: Honeybees are important pollinators worldwide, with their gut microbiota playing a crucial role in maintaining their health. The gut bacteria of honeybees consist of primarily five core lineages that are spread through social interactions ...
Shiqi Luo, Xue Zhang, Xin Zhou
doaj   +1 more source

Evolutionary Genomics of Staphylococcus aureus Reveals Insights into the Origin and Molecular Basis of Ruminant Host Adaptation [PDF]

, 2010
Phenotypic biotyping has traditionally been used to differentiate bacteria occupying distinct ecological niches such as host species. For example, the capacity of Staphylococcus aureus from sheep to coagulate ruminant plasma, reported over 60 years ago ...
Fitzgerald J.R., Smyth, D.S., Jodi A. Lindsay, Lindsay, J.A., Hinds, Jason, Davida S. Smyth, Tormo-Mas, Maria A, Gould, Katherine A, Jonathan P. Bollback, Rambaut, A, Ben Zakour, N.L., Cyril J Smyth, Fitzgerald, Ross; id_orcid, Lowder, Bethan V., Hinds J., Penades, Jose R, J Ross Fitzgerald, Witney, A., Rambaut A., Katherine A. Gould, Hinds, J, Bollback, J.P., Jason Hinds, J. Ross Fitzgerald, Tormo-Mas, María A., Smyth D.S., Nouri L Ben Zakour, Penades J.R., Jonathan P Bollback, Weinert, Lucy A, Caitriona M. Guinane, Nouri L. Ben Zakour, Bethan V Lowder, Smyth, Davida S, Davida S Smyth, Gould, KA, Guinane, C.M., Rambaut, A., Lowder B.V., Lowder, BV, Cartwright, R.A., Fitzgerald, J. Ross, Lindsay, Jodi A, Cyril J. Smyth, Cartwright R.A., Tormo-Mas, MA, Ben Zakour, Nouri L., Weinert, LA, Tormo-Mas, M.A., Gould, Katherine A., Maria A. Tormo-Mas, Caitriona M Guinane, Penades, JR, Smyth, Cyril J., Gould, K.A., Smyth, C.J., Smyth, Cyril J, Cartwright, RA, Lucy A. Weinert, Fitzgerald, JR, Penades, J.R., Cartwright, Robyn, Bethan V. Lowder, Ben Zakour, NL, Lindsay, JA, Smyth C.J., Andrew Rambaut, Gould K.A., Jodi A Lindsay, Weinert, Lucy A., Guinane, Caitriona M., Witney, Adam, Bollback J.P., Hinds, J., Bollback, Jonathan P., Lowder, Bethan V, Guinane, CM, Katherine A Gould, Witney, A, Guinane C.M., Lowder, B.V., Weinert L.A., Lindsay J.A., Robyn A. Cartwright, Tormo-Mas M.A., Maria A Tormo-Mas, Lindsay, Jodi A., Smyth, DS, Weinert, L.A., Bollback, Jonathan P, Lucy A Weinert, Ben Zakour, Nouri L, Bollback, JP, Witney A., Rambaut, Andrew, Penadés, José R., Smyth, CJ, Zakour N.L.B., José R Penadé S, Guinane, Caitriona M, Fitzgerald, J.R., Cartwright, Robyn A, Fitzgerald, J Ross, Adam Witney, Cartwright, Robyn A., Robyn A Cartwright, José R. Penadés   +106 more
core   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source