Results 81 to 90 of about 821,546 (355)
Host range and specificity of the Drosophila C virus.
PLoS ONE, 2010 BackgroundThe Drosophila C virus (DCV) is a common and well-studied Drosophila pathogen. Although natural infections are known from Drosophila melanogaster and D.
Martin Kapun +3 more
doaj +1 more source
Viral factors in influenza pandemic risk assessment [PDF]
, 2016 The threat of an influenza A virus pandemic stems from continual virus spillovers from reservoir species, a tiny fraction of which spark sustained transmission in humans.
Barclay, Wendy +18 more
core +4 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Comparative Biology of Temperate and Subtropical Bark and Ambrosia Beetles (Coleoptera: Scolytidae, Platypodidae) in Indiana and Florida [PDF]
, 2017 Bark and ambrosia beetles were compared from two intensively studied sites. The Indiana site produced 58 species, the Florida site 57 species; 17 species occurred at both sites. Much greater plant host diversity at the Indiana site seems balanced by more
Atkinson, Thomas H, Deyrup, Mark
core +2 more sources
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
IMA Fungus, 2021 The relationship between entomopathogenic fungi and their insect hosts is a classic example of the co-evolutionary arms race between pathogen and target host.
Agata Kaczmarek, Mieczysława I. Boguś
doaj +1 more source
Non-Target Feeding by Galerucella Calmariensis on Sandbar Willow (Salix Interior) in Illinois [PDF]
, 2018 Purple loosestrife, Lythrum salicaria L., is an introduced Eurasian perennial herb that has been in North America since the early 1800s (Thompson et al. 1987).
Wiedenmann, Robert N
core +3 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source