The Osmium Isotope Signature of Phanerozoic Large Igneous Provinces
Geophysical Monograph Series, Page 229-246., 2021 Exploring the links between Large Igneous Provinces and dramatic environmental impact
An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
Alexander J. Dickson +2 more
wiley +4 more sources
Hot-melt extrusion: process to novel pharmaceutical applications
, 2013 Over the last three decades industrial adaptability has allowed hot-melt extrusion (HME) to gain wide acceptance and has already established its place in the broad spectrum of manufacturing operations and pharmaceutical research development.
Mohammed Maniruzzaman (1626004)
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Journal of Applied Pharmaceutical ResearchBackground: Conversion of poorly soluble drugs into amorphous solid dispersions using different carriers is a formulation approach to improve solubility.
Lakshmi Swapna Sai +3 more
doaj +1 more source
Advanced Science, EarlyView.Dual priming with minocycline and photodynamic priming reprograms the pancreatic tumor microenvironment to overcome chemoresistance. By suppressing DNA repair enzyme Tdp1, inducing photooxidative damage, and enhancing irinotecan delivery via light‐activated nanoencapsulation, this strategy remodels the tumor microenvironment and drives immune ...
Fernanda V. Cabral +7 more
wiley +1 more source
Effect of particle size on release of solid dispersed particles during the "Dissolution" test
Разработка и регистрация лекарственных средствIntroduction. The use of the solid disperse systems method to increase the solubility of lipophilic active pharmaceutical ingredients is industrially applicable using different technologies, but the influence of particle size on the dissolution of these ...
S. A. Zolotov, A. V. Panov
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Ultra‐Low Intensity Continuous Wave Laser Ablation Propulsion With Graphene‐Engineered Wood
Advanced Science, EarlyView.Graphene delignified wood converts continuous wave laser energy into thrust. Laser propulsion experiments in vacuum reveal the lowest laser ablation threshold intensities and the greatest density‐normalized specific impulse in literature. The results highlight graphene delignified wood as a potential efficient, sustainable, strong, and lightweight ...
Afnan S. M. Elmubasher +10 more
wiley +1 more source
Modified release formulations manufactured by hot-melt extrusion
, 2020 Hot-melt-extrusion has recently gained interest in pharmaceutical industrial manufacturing due to numerous advantages such as the possibility for continuous manufacturing, low cost of operation or the absence of organic solvents.
Maincent, Julien
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Advanced Science, EarlyView.A metal‐directed carbonization strategy transforms hierarchical organic microspheres into spiky carbon catalysts with Pd nanoparticles embedded at the tips. This approach resolves the activity‐stability trade‐off, achieving exceptional poison resistance in semi‐hydrogenations, offering a versatile, scalable platform for designing high‐performance ...
Yintao Li +9 more
wiley +1 more source
Hot melt extrusion: An industrially feasible approach for casting orodispersible film
Asian Journal of Pharmaceutical Sciences, 2015 Over the recent few decades, many groups of formulation scientists are concentrating on rapid release dosage forms in oral cavity. Among all fast release dosage forms, orodispersible films are successful to attract pharmaceutical industry due to ease of ...
Rushiraj Jani, Dasharath Patel
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Enhancing the oral drug delivery through hot melt extrusion techniques
, 2022 Hot melt extrusion has been developed as a fresh technique for taste masking, in recent years. This method provides many aids as compared to traditional methods like avoiding the use of solvents, continuous manufacturing, ease to scale up, and ...
Komanduri, Neeraja
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