Results 101 to 110 of about 16,706 (282)
Biodegradable Zn‐Based Implants: Progress, Challenges, and Pathways toward Clinical Translation
Advanced Science, EarlyView.Exploring biodegradable Zn‐based implants offers a promising pathway to next‐generation biomedical devices with balanced degradation and biocompatibility. A comprehensive overview of biodegradable Zn‐based implants, covering their biological significance, material design principles, and advanced engineering strategies is provided.
Panfeng Zhao +10 more
wiley +1 more source
Journal of Excipients and Food Chemicals, 2022 The aim of this work was to improve the solubility of various anti-HIV APIs extruding them with polyvinyl alcohol to allow a reduction in patient drug burden. There are no previously known cases of successful use of this polymer to improve the solubility
Sergey A Zolotov +6 more
doaj
Enhancing the bioavailability of hydrophobic drugs using hot melt extrusion [PDF]
, 2018 Many existing drugs (as well as new revelations) in the pharmaceutical industry bear a distinct disadvantage in the sense that they are not water soluble, displaying low bioavailability values and consequently a reduced invitro effect. Hot melt extrusion
Coffey, Conor +3 more
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New Natural Injection-Moldable Composite Material from Sunflower Oil Cake [PDF]
, 2006 Through a twin-screw extrusion process the native structure of sunflower oil cake was completely transformed (globular protein denaturation/texturization and husk fiber defibration) into a simpler matrix-fiber structure, as could be seen on SEM ...
O. Orliac +7 more
core +1 more source
Synthesis of functionalized polyolefins in a new continuous bench‐scale reactor apparatus
AIChE Journal, EarlyView.Abstract In‐reactor functionalized polyolefins (FPOs), produced by molecular catalysts, are a new class of polymer materials with applications ranging from high performance adhesives to bitumen compatibilization. In this work, we disclose a procedure for the synthesis of FPOs in a new Continuous Bench‐scale Reactor Apparatus (COBRA).
Miloud Bouyahyi +7 more
wiley +1 more source
Hot-melt co-extrusion as manufacturing technique for multilayer oral dosage forms [PDF]
, 2014 Co-extrusion implies the simultaneous hot-melt extrusion of two or more materials through the same die, creating a multilayered extrudate. This innovative continuous production technology offers numerous advantages over traditional pharmaceutical ...
Dierickx, Lien
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Advanced Experiment Design Strategies for Drug Development
Advanced Intelligent Discovery, EarlyView.Wang et al. analyze 592 drug development studies published between 2020 and 2024 that applied design of experiments methodologies. The review surveys both classical and emerging approaches—including Bayesian optimization and active learning—and identifies a critical gap between advanced experimental strategies and their practical adoption in ...
Fanjin Wang +3 more
wiley +1 more source
Properties of polymeric drug delivery systems prepared by hot-melt extrusion [PDF]
, 2002 textThe purpose of this research project was to investigate the physicochemical and drug release properties of polymeric drug delivery systems prepared by hot-melt extrusion containing either highly water-soluble drugs or a poorly water-soluble drug. The
Zhu, Yucun
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Micro-extrusion of fine ceramic latticework
, 2008 PhDMicroextrusion freeforming of ceramic lattices from high solids ceramic pastes is a method for forming complex multi-scale hierarchical porous structures.
Chi, Xiaopeng
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Preparation of different dosage forms utilizing hot melt extrusion technology for oral delivery
, 2022 Hot melt extrusion technology has been prevalent in the pharmaceutical industry for the mixing, compounding and processing of materials. Due to the adaptability and versatility of the twin screw extruder, the hot melt extrusion process has been widely ...
Srinivasan, Priyanka
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